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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Progesterone receptor membrane component-1 regulates hepcidin biosynthesis

Authors:
Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT
Citation:
J Clin Invest. 2015 Dec 14. pii: 83831. doi: 10.1172/JCI83831. [Epub ahead of print]
Epub:
Yes
Abstract:
Iron homeostasis is tightly regulated by the membrane iron exporter ferroportin and its regulatory peptide hormone hepcidin....
Link:
http://www.jci.org/articles/view/83831
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT. Progesterone receptor membrane component-1 regulates hepcidin biosynthesis. J Clin Invest. 2015 Dec 14. pii: 83831. doi: 10.1172/JCI83831. [Epub ahead of print].

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

Authors:
de Bruin A, Cornelissen PWA, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang K-H, Végh AMD, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ
Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv1471
Epub:
Yes
Abstract:
In this study, we explored the existence of a transcriptional network co-regulated by E2F7 and HIF1α, as we show that...
Link:
http://nar.oxfordjournals.org/content/early/2015/12/17/nar.gkv1471.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Bruin A, Cornelissen PWA, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang K-H, Végh AMD, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ. Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv1471.

MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome

Authors:
Chiavacci E, D'Aurizio R, Guzzolino E, Russo F, Baumgart M, Groth M, Mariani L, D'Onofrio M, Arisi I, Pellegrini M, Cellerino A, Cremisi F, Pitto L
Citation:
Sci Rep. 2015 Dec 14;5:18240. doi: 10.1038/srep18240
Epub:
Not Epub
Abstract:
Holt-Oram Syndrome (HOS) is an autosomal dominant heart-hand syndrome caused by mutations in the TBX5 gene, a transcription...
Link:
http://www.nature.com/articles/srep18240
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiavacci E, D'Aurizio R, Guzzolino E, Russo F, Baumgart M, Groth M, Mariani L, D'Onofrio M, Arisi I, Pellegrini M, Cellerino A, Cremisi F, Pitto L. MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome. Sci Rep. 2015 Dec 14;5:18240. doi: 10.1038/srep18240.

Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis

Authors:
Overton JD, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, Fedeles SV, Habas R, Runnels LW
Citation:
Sci Rep. 2015 Dec 16;5:18395. doi: 10.1038/srep18395
Epub:
Not Epub
Abstract:
Mutations in protein kinase C substrate 80K-H (PRKCSH), which encodes for an 80 KDa protein named hepatocystin (80K-H, PRKCSH...
Link:
http://www.nature.com/articles/srep18395
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Overton JD, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, Fedeles SV, Habas R, Runnels LW. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Sci Rep. 2015 Dec 16;5:18395. doi: 10.1038/srep18395.

Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos

Authors:
Li J, Yue Y, Zhao Q
Citation:
Zebrafish. 2015 Dec 15. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid (RA) plays important roles in many stages of heart morphogenesis. Zebrafish embryos treated with exogenous RA...
Link:
http://online.liebertpub.com/doi/10.1089/zeb.2015.1117
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Yue Y, Zhao Q. Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos. Zebrafish. 2015 Dec 15. [Epub ahead of print].

Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection

Authors:
Ningappa M, Ashokkumar C, Higgs BW, Sun Q, Jaffe R, Mazariegos G, Li D, Weeks DE, Subramaniam S, Ferrell R, Hakonarson H, Sindhi R
Citation:
Am J Transplant. 2015 Dec 11. doi: 10.1111/ajt.13509. [Epub ahead of print]
Epub:
Yes
Abstract:
T cell suppression prevents acute cellular rejection but causes life-threatening infections and malignancies. Previously, liver...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/ajt.13509/abstract
Organism or Cell Type:
cell culture: lymphoblastoid B cells (Raji cells)
Citation Extract:
Ningappa M, Ashokkumar C, Higgs BW, Sun Q, Jaffe R, Mazariegos G, Li D, Weeks DE, Subramaniam S, Ferrell R, Hakonarson H, Sindhi R. Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection. Am J Transplant. 2015 Dec 11. doi: 10.1111/ajt.13509. [Epub ahead of print].

Pou5f3.2-induced proliferative state of embryonic cells during gastrulation of Xenopus laevis embryo

Authors:
Nishitani E, Li C, Lee J, Hotta H, Katayama Y, Yamaguchi M, Kinoshita T
Citation:
Dev Growth Differ. 2015 Dec 14. doi: 10.1111/dgd.12246. [Epub ahead of print]
Epub:
Yes
Abstract:
POU class V (POU-V) transcription factors play the important role in maintenance of pluripotency and cell differentiation....
Link:
http://onlinelibrary.wiley.com/doi/10.1111/dgd.12246/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nishitani E, Li C, Lee J, Hotta H, Katayama Y, Yamaguchi M, Kinoshita T. Pou5f3.2-induced proliferative state of embryonic cells during gastrulation of Xenopus laevis embryo. Dev Growth Differ. 2015 Dec 14. doi: 10.1111/dgd.12246. [Epub ahead of print].

Neurogenic gene regulatory pathways in the sea urchin embryo

Authors:
Wei Z, Angerer LM, Angerer RC
Citation:
Development. 2015 Dec 10. pii: dev.125989. [Epub ahead of print]
Epub:
Yes
Abstract:
During embryogenesis the sea urchin early pluteus larva differentiates 40-50 neurons marked by expression of the pan-neural...
Link:
http://dev.biologists.org/content/early/2015/12/07/dev.125989.long
Organism or Cell Type:
sea urchin
Citation Extract:
Wei Z, Angerer LM, Angerer RC. Neurogenic gene regulatory pathways in the sea urchin embryo. Development. 2015 Dec 10. pii: dev.125989. [Epub ahead of print].

Tumor Suppressor Lzap Suppresses Wnt/β-catenin signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of GSK3

Authors:
Lin KY, Kao SH, Lai CM, Chen CT, Wu CY, Hsu HJ, Wang WD
Citation:
J Biol Chem. 2015 Oct 16. pii: jbc.M115.669309. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling controls various cell fates in metazoan development, and its dysregulation is often associated with...
Link:
http://www.jbc.org/content/290/50/29808.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin KY, Kao SH, Lai CM, Chen CT, Wu CY, Hsu HJ, Wang WD. Tumor Suppressor Lzap Suppresses Wnt/β-catenin signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of GSK3. J Biol Chem. 2015 Oct 16. pii: jbc.M115.669309. [Epub ahead of print].

Morpholino antisense oligo inhibits trans-splicing of pre-inositol 1,4,5-trisphosphate receptor mRNA of Trypanosoma cruzi and suppresses parasite growth and infectivity

Authors:
Hashimoto M, Nara T, Mita T, Mikoshiba K
Citation:
Parasit Internat. 2015;[Epub ahead of print] doi:10.1016/j.parint.2015.12.001
Epub:
Yes
Abstract:
Morpholino antisense oligos (MAOs) are used to investigate physiological gene function by inhibiting gene translation or...
Link:
http://www.sciencedirect.com/science/article/pii/S1383576915001968
Organism or Cell Type:
Trypanosoma cruzi
Citation Extract:
Hashimoto M, Nara T, Mita T, Mikoshiba K. Morpholino antisense oligo inhibits trans-splicing of pre-inositol 1,4,5-trisphosphate receptor mRNA of Trypanosoma cruzi and suppresses parasite growth and infectivity. Parasit Internat. 2015;[Epub ahead of print] doi:10.1016/j.parint.2015.12.001.

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