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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Cartilage development requires the function of Estrogen-related receptor alpha that directly regulates sox9 expression in zebrafish

Authors:
Kim Y-I, Lee JN, Bhandari S, Nam I-K, Yoo K-W, Kim S-J, Oh G-S, Kim H-J, So H-S, Choe S-K,Park R
Citation:
Sci Reb. 2015;5:18011. doi:10.1038/srep18011
Epub:
Not Epub
Abstract:
Estrogen-related receptor alpha (ESRRa) regulates a number of cellular processes including development of bone and muscles....
Link:
http://www.nature.com/articles/srep18011
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim Y-I, Lee JN, Bhandari S, Nam I-K, Yoo K-W, Kim S-J, Oh G-S, Kim H-J, So H-S, Choe S-K,Park R. Cartilage development requires the function of Estrogen-related receptor alpha that directly regulates sox9 expression in zebrafish. Sci Reb. 2015;5:18011. doi:10.1038/srep18011.

Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure

Authors:
McMillin M, Frampton G, Quinn M, Ashfaq S, de los Santos III M, Grant S, DeMorrow S
Citation:
Am J Pathol. 2015;186(2):312–23. doi:10.1016/j.ajpath.2015.10.005
Epub:
Yes
Abstract:
Hepatic encephalopathy is a serious neurological complication of liver failure. Serum bile acids are elevated after liver...
Link:
http://ajp.amjpathol.org/article/S0002-9440%2815%2900587-8/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
McMillin M, Frampton G, Quinn M, Ashfaq S, de los Santos III M, Grant S, DeMorrow S. Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure. Am J Pathol. 2015;186(2):312–23. doi:10.1016/j.ajpath.2015.10.005.

Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish

Authors:
Griffin A, Parajes S, Weger M, Zaucker A, Taylor AE, O'Neil DM, Müller F, Krone N
Citation:
Endocrinology. 2015 Dec 9:en20151480. [Epub ahead of print]
Epub:
Yes
Abstract:
Mitochondrial cytochrome P450 (CYP) enzymes rely on electron transfer from the redox partner ferredoxin (FDX1) for catalytic...
Link:
http://press.endocrine.org/doi/10.1210/en.2015-1480
Organism or Cell Type:
zebrafish
Citation Extract:
Griffin A, Parajes S, Weger M, Zaucker A, Taylor AE, O'Neil DM, Müller F, Krone N. Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish. Endocrinology. 2015 Dec 9:en20151480. [Epub ahead of print].

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

Authors:
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LCF, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK
Citation:
Cell Host & Microbe. 2015;18(6):723-35. doi:10.1016/j.chom.2015.11.002
Epub:
Not Epub
Abstract:
Several systems-level datasets designed to dissect host-pathogen interactions during influenza A infection have been reported....
Link:
http://www.cell.com/cell-host-microbe/abstract/S1931-3128%2815%2900456-4
Delivery Method:
peptide-linked
Organism or Cell Type:
BALB/c mice
Citation Extract:
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LCF, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK. Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding. Cell Host & Microbe. 2015;18(6):723-35. doi:10.1016/j.chom.2015.11.002.

Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos

Authors:
Lee H-C, Lo H-C, Lo D-M, Su M-Y, Hu J-R, Wu C-C, Chang S-N, Dai M-S, Tsai C-T, Tsai H-J
Citation:
PLoS ONE. 2015;10(12):e0144751. doi:10.1371/journal.pone.0144751
Epub:
Not Epub
Abstract:
Although Amiodarone, a class III antiarrhythmic drug, inhibits zebrafish cardiac valve formation, the detailed molecular...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144751
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee H-C, Lo H-C, Lo D-M, Su M-Y, Hu J-R, Wu C-C, Chang S-N, Dai M-S, Tsai C-T, Tsai H-J. Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos. PLoS ONE. 2015;10(12):e0144751. doi:10.1371/journal.pone.0144751.

TGF-β Controls miR-181/ERK Regulatory Network during Retinal Axon Specification and Growth

Authors:
Carrella S, Barbato S, D'Agostino Y, Salierno FG, Manfredi A, Banfi S, Conte I
Citation:
PLoS One. 2015 Dec 7;10(12):e0144129. doi: 10.1371/journal.pone.0144129. eCollection 2015
Epub:
Not Epub
Abstract:
Retinal axon specification and growth are critically sensitive to the dosage of numerous signaling molecules and transcription...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144129
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Carrella S, Barbato S, D'Agostino Y, Salierno FG, Manfredi A, Banfi S, Conte I. TGF-β Controls miR-181/ERK Regulatory Network during Retinal Axon Specification and Growth. PLoS One. 2015 Dec 7;10(12):e0144129. doi: 10.1371/journal.pone.0144129. eCollection 2015.

POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking

Authors:
Schindler RF, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon KL, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T, Ferlini A
Citation:
J Clin Invest. 2015 Dec 7. pii: 79562. doi: 10.1172/JCI79562. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Popeye domain-containing 1 (POPDC1) gene encodes a plasma membrane-localized cAMP-binding protein that is abundantly...
Link:
http://www.jci.org/articles/view/79562
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schindler RF, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon KL, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T, Ferlini A. POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking. J Clin Invest. 2015 Dec 7. pii: 79562. doi: 10.1172/JCI79562. [Epub ahead of print].

The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells

Authors:
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G
Citation:
J Cell Biol. 2015;211(5):964-73. doi:10.1083/jcb.201502043
Epub:
Not Epub
Abstract:
Motile cilia polarization requires intracellular anchorage to the cytoskeleton; however, the molecular machinery that supports...
Link:
http://jcb.rupress.org/content/211/5/963.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G. The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. J Cell Biol. 2015;211(5):964-73. doi:10.1083/jcb.201502043.

Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type

Authors:
Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, Koparir E, Karaca E, Katsanis N, Marton V, Vermeesch JR, Davis EE, Cowan NJ, Keays DA, Van Esch H
Citation:
Am J Hum Gen. 2015;97(6):790-800. doi:10.1016/j.ajhg.2015.10.014
Epub:
Not Epub
Abstract:
Circumferential skin creases Kunze type (CSC-KT) is a specific congenital entity with an unknown genetic cause. The disease...
Link:
http://www.sciencedirect.com/science/article/pii/S0002929715004164
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, Koparir E, Karaca E, Katsanis N, Marton V, Vermeesch JR, Davis EE, Cowan NJ, Keays DA, Van Esch H. Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type. Am J Hum Gen. 2015;97(6):790-800. doi:10.1016/j.ajhg.2015.10.014.

PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination

Authors:
Kim J-D, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A
Citation:
Sci Adv. 2015;1:e1500615 doi:10.1126/sciadv.1500615
Epub:
Not Epub
Abstract:
The development of vertebrate neurons requires a change in membrane phosphatidylcholine (PC) metabolism. Although PC hydrolysis...
Link:
http://advances.sciencemag.org/content/1/11/e1500615
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim J-D, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A. PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination. Sci Adv. 2015;1:e1500615 doi:10.1126/sciadv.1500615.

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