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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Longitudinal effect of eteplirsen vs. historical control on ambulation in DMD
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Citation:
Ann Neurol. 2015;[Epub ahead of print] doi:10.1002/ana.24555 Epub:
Yes Abstract:
Objectives: To continue evaluation of the long-term efficacy and safety of eteplirsen, a phosphorodiamidate morpholino oligomer... Delivery Method:
infusion i.v. Organism or Cell Type:
humans Citation Extract: Mendell JR, Goemans N, Lowes LP, Alfano LN, Berry K, Shao J, Kaye EM, Mercuri E, Eteplirsen Study Group, DMD Italian Network. Longitudinal effect of eteplirsen vs. historical control on ambulation in DMD. Ann Neurol. 2015;[Epub ahead of print] doi:10.1002/ana.24555. |
Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells
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Citation:
Skeletal Muscle. 2015;5:40. doi:10.1186/s13395-015-0062-6 Epub:
Not Epub Abstract:
Background: Duchenne muscular dystrophy (DMD) is a devastating X-linked recessive genetic myopathy. DMD physiopathology is... Delivery Method:
electroporation Organism or Cell Type:
cell culture: hiPSCs Citation Extract: Massouridès E, Polentes J, Mangeot P-E, Mournetas V, Nectoux J, Deburgrave N, Nusbaum P, Leturcq F, Popplewell L, Dickson G, Wein N, Flanigan KM, Peschanski M, Chelly J, Pinset C. Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells. Skeletal Muscle. 2015;5:40. doi:10.1186/s13395-015-0062-6. |
Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway
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Citation:
Sci Rep. 2015;5:16815. doi:10.1038/srep16815 Epub:
Not Epub Abstract:
Formononetin is an isoflavone that has been shown to display estrogenic properties and induce angiogenesis activities. However... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li S, Dang Y, Zhou X, Huang B, Huang X, Zhang Z, Kwan YW, Chan SW, Leung GPH, Lee SMY, Hoi MPM. Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway. Sci Rep. 2015;5:16815. doi:10.1038/srep16815. |
The Effects of Hsp90α1 Mutations on Myosin Thick Filament Organization
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Citation:
PLoS ONE. 2015;10(11):e0142573. doi:10.1371/journal.pone.0142573 Epub:
Not Epub Abstract:
Heat shock protein 90α plays a key role in myosin folding and thick filament assembly in muscle cells. To assess the structure... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He Q, Liu K, Tian Z, Du SJ. The Effects of Hsp90α1 Mutations on Myosin Thick Filament Organization. PLoS ONE. 2015;10(11):e0142573. doi:10.1371/journal.pone.0142573. |
Individual Members of the Microbiota Disproportionately Modulate Host Innate Immune Responses
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Citation:
Cell Host Microbe. 2015;18(5):613-20. doi:10.1016/j.chom.2015.10.009 Epub:
Not Epub Abstract:
Predicting host health status based on microbial community structure is a major goal of microbiome research. An implicit... Organism or Cell Type:
zebrafish Citation Extract: Rolig AS, Parthasarathy R, Burns AR, Bohannan BJM, Guillemin K. Individual Members of the Microbiota Disproportionately Modulate Host Innate Immune Responses. Cell Host Microbe. 2015;18(5):613-20. doi:10.1016/j.chom.2015.10.009. |
Identification of microRNAs and microRNA Targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1
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Citation:
Dev Biol. 2015 Nov 5. pii: S0012-1606(15)30277-3. doi: 10.1016/j.ydbio.2015.11.005. [Epub ahead of print] Epub:
Yes Abstract:
MicroRNAs (miRNAs) are known to play diverse roles in the regulation of vertebrate development. To investigate miRNA-target... Organism or Cell Type:
Xenopus laevis Citation Extract: Liu C, Lou CH, Shah V, Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK. Identification of microRNAs and microRNA Targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1. Dev Biol. 2015 Nov 5. pii: S0012-1606(15)30277-3. doi: 10.1016/j.ydbio.2015.11.005. [Epub ahead of print]. |
Ancestral mesodermal reorganization and evolution of the vertebrate head
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Citation:
Zoo Lett. 2015;1:29 doi:10.1186/s40851-015-0030-3 Epub:
Not Epub Abstract:
Introduction: The vertebrate head is characterized by unsegmented head mesoderm the evolutionary origin of which remains... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Onai T, Aramaki T, Inomata H, Hirai T, Kuratani S. Ancestral mesodermal reorganization and evolution of the vertebrate head. Zoo Lett. 2015;1:29 doi:10.1186/s40851-015-0030-3. |
Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways
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Citation:
Dev Biol. 2015 Nov 3. pii: S0012-1606(15)30271-2. doi: 10.1016/j.ydbio.2015.11.002. [Epub ahead of print] Epub:
Yes Abstract:
In humans, genetic diseases affecting skin integrity (genodermatoses) are generally caused by mutations in a small number of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Noiret M, Mottier S, Angrand G, Gautier-Courteille C, Lerivray H, Viet J, Paillard L, Mereau A, Hardy S, Audic Y. Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways. Dev Biol. 2015 Nov 3. pii: S0012-1606(15)30271-2. doi: 10.1016/j.ydbio.2015.11.002. [Epub ahead of print]. |
Mutation of the mitochondrial carrier SLC25A42 causes a novel form of mitochondrial myopathy in humans
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Citation:
Hum Genet. 2015 Nov 5. [Epub ahead of print] Epub:
Yes Abstract:
Myopathies are heterogeneous disorders characterized clinically by weakness and hypotonia, usually in the absence of gross... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shamseldin HE, Smith LL, Kentab A, Alkhalidi H, Summers B, Alsedairy H, Xiong Y, Gupta VA, Alkuraya FS. Mutation of the mitochondrial carrier SLC25A42 causes a novel form of mitochondrial myopathy in humans. Hum Genet. 2015 Nov 5. [Epub ahead of print]. |
ACAM, a novel member of the neural IgCAM family, mediates anterior neural tube closure in a primitive chordate
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Citation:
Dev Biol. 2015 Nov 2. pii: S0012-1606(15)30191-3. doi: 10.1016/j.ydbio.2015.10.032. [Epub ahead of print] Epub:
Not Epub Abstract:
The neural IgCAM family of cell adhesion molecules, which includes NCAM and related molecules, has evolved via gene duplication... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Morales Diaz H, Mejares E, Newman-Smith E, Smith WC. ACAM, a novel member of the neural IgCAM family, mediates anterior neural tube closure in a primitive chordate. Dev Biol. 2015 Nov 2. pii: S0012-1606(15)30191-3. doi: 10.1016/j.ydbio.2015.10.032. [Epub ahead of print]. |