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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)
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Citation:
J Med Genet. 2015 Nov;52(11):738-48. doi: 10.1136/jmedgenet-2015-103292. Epub 2015 Sep 4 Epub:
Not Epub Abstract:
BACKGROUND: Deadenylation regulates RNA function and fate. Poly(A)-specific ribonuclease (PARN) is a deadenylase that processes... Organism or Cell Type:
zebrafish Citation Extract: Dhanraj S, Gunja SM, Deveau AP, Nissbeck M, Boonyawat B, Coombs AJ, Renieri A, Mucciolo M, Marozza A, Buoni S, Turner L, Li H, Jarrar A, Sabanayagam M, Kirby M, Shago M, Pinto D, Berman JN, Scherer SW, Virtanen A, Dror Y. Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN). J Med Genet. 2015 Nov;52(11):738-48. doi: 10.1136/jmedgenet-2015-103292. Epub 2015 Sep 4. |
Modulating expression level of secreted Wnt3 influences cerebellum development in zebrafish transgenics
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Citation:
Development. 2015 Sep 22. pii: dev.127589. [Epub ahead of print] Epub:
Not Epub Abstract:
The boundaries of brain regions are associated with the tissue-specific secretion of ligands from different signalling pathways... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Teh C, Sun G, Shen H, Korzh V, Wohland T. Modulating expression level of secreted Wnt3 influences cerebellum development in zebrafish transgenics. Development. 2015 Sep 22. pii: dev.127589. [Epub ahead of print]. |
DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint
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Citation:
Nat Comm. 2015;6:8553. doi:10.1038/ncomms9553 Epub:
Not Epub Abstract:
Extensive damage to maternal DNA during meiosis causes infertility, birth defects and abortions. However, it is unknown if... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Collins JK,. Lane SIR, Merriman JA, Jones KT. DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint. Nat Comm. 2015;6:8553. doi:10.1038/ncomms9553. |
DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age
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Citation:
Nat Comm. 2015;6:8706. doi:10.1038/ncomms9706 Epub:
Not Epub Abstract:
In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to infertility and developmental... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Marangos P, Stevense M, Niaka K, Lagoudaki M, Nabti I, Jessberger R, John Carroll J. DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age. Nat Comm. 2015;6:8706. doi:10.1038/ncomms9706. |
Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development
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Citation:
Mol Biol Cell. 2015 Nov 1;26(21):3728-40. doi: 10.1091/mbc.E15-02-0112. Epub 2015 Sep 9 Epub:
Not Epub Abstract:
During development, vagal neural crest cells fated to contribute to the enteric nervous system migrate ventrally away from the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Uribe RA, Bronner ME. Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development. Mol Biol Cell. 2015 Nov 1;26(21):3728-40. doi: 10.1091/mbc.E15-02-0112. Epub 2015 Sep 9. |
A zebrafish model of Poikiloderma with Neutropenia recapitulates the human syndrome hallmarks and traces back neutropenia to the myeloid progenitor
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Citation:
Sci Rep. 2015;5:15814. doi:10.1038/srep15814 Epub:
Not Epub Abstract:
Poikiloderma with Neutropenia (PN) is an autosomal recessive genodermatosis characterized by early-onset poikiloderma,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Colombo EA, Carra S, Fontana L, Bresciani E, Cotelli F, Larizza L. A zebrafish model of Poikiloderma with Neutropenia recapitulates the human syndrome hallmarks and traces back neutropenia to the myeloid progenitor. Sci Rep. 2015;5:15814. doi:10.1038/srep15814. |
Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms
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Citation:
Development. 2015 Oct 28. pii: dev.124503. [Epub ahead of print] Epub:
Yes Abstract:
A single origin to the diverse mechanisms of metazoan neurogenesis is suggested by the involvement of common signaling... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Garner S, Zysk I, Byrne G, Kramer M, Moller D, Taylor V, Burke RD. Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms. Development. 2015 Oct 28. pii: dev.124503. [Epub ahead of print]. |
Production of reproductively sterile fish by a non-transgenic gene silencing technology
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Citation:
Sci Rep. 2015 Oct 29;5:15822. doi: 10.1038/srep15822 Epub:
Not Epub Abstract:
We developed a novel bath-immersion technology to produce large numbers of infertile fish. As seafood consumption shifts from... Delivery Method:
Vivo-Morpholino bathing Organism or Cell Type:
zebrafish Citation Extract: Wong TT, Zohar Y. Production of reproductively sterile fish by a non-transgenic gene silencing technology. Sci Rep. 2015 Oct 29;5:15822. doi: 10.1038/srep15822. |
Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells
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Citation:
J Biomed Nanotechnol. 2015 Dec;11(12):2111-23 Epub:
Not Epub Abstract:
For the first time the efficiency of gene knockdown of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: rat PC12 Citation Extract: Deng W, Farnham MM, Goldys EM, Mohammed S, Pilowsky PM. Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells. J Biomed Nanotechnol. 2015 Dec;11(12):2111-23. |
klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes
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Citation:
PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015 Epub:
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INTRODUCTION AND OBJECTIVES: The zinc-finger transcription factor Krϋppel-like factor 2 (KLF2) transduces blood flow into... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Novodvorsky P, Watson O, Gray C, Wilkinson RN, Reeve S, Smythe C, Beniston R, Plant K, Maguire R, M K Rothman A, Elworthy S, van Eeden FJ, Chico TJ. klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015. |