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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
microRNA-31 modulates skeletal patterning in the sea urchin embryo
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Citation:
Development. 2015 Nov 1;142(21):3769-80. doi: 10.1242/dev.127969. Epub 2015 Sep 23 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that repress the translation and reduce the stability of target mRNAs in animal... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Stepicheva NA, Song JL. microRNA-31 modulates skeletal patterning in the sea urchin embryo. Development. 2015 Nov 1;142(21):3769-80. doi: 10.1242/dev.127969. Epub 2015 Sep 23. |
CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus
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Citation:
Dev Biol. 2015 Nov 4. pii: S0012-1606(15)30269-4. doi: 10.1016/j.ydbio.2015.11.003. [Epub ahead of print] Epub:
Yes Abstract:
Congenital malformations are the major cause of infant mortality in the US and Europe. Due to rapid advances in human genomics... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Bhattacharya D, Marfo CA, Li D, Lane M, Khokha MK. CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus. Dev Biol. 2015 Nov 4. pii: S0012-1606(15)30269-4. doi: 10.1016/j.ydbio.2015.11.003. [Epub ahead of print]. |
Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin–Siris syndrome
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Citation:
J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2015-103393 Epub:
Yes Abstract:
Background: SOX11 is a transcription factor proposed to play a role in brain development. The relevance of SOX11 to human... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hempel A, Pagnamenta AT, Blyth M, Mansour S, McConnell V, Kou I, Shiro I, Tsurusaki Y, Matsumoto N, Lo-Castro A, Plessis G, Albrecht B, Battaglia A, Taylor JC, Howard MF, Keays D, Sohal AS, DDD collaboration, Kühl SJ, Kini U, McNeill A. Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin–Siris syndrome. J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2015-103393 . |
Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived Conditions
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Citation:
PLoS One. 2015 Nov 5;10(11):e0142280. doi: 10.1371/journal.pone.0142280. eCollection 2015 Epub:
Not Epub Abstract:
Thioredoxin-2 (Trx2) is a mitochondrial protein using a dithiol active site to reduce protein disulfides. In addition to the... Delivery Method:
injection then electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Pirson M, Debrulle S, Clippe A, Clotman F, Knoops B. Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived Conditions. PLoS One. 2015 Nov 5;10(11):e0142280. doi: 10.1371/journal.pone.0142280. eCollection 2015. |
CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart
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Citation:
J Cell Sci. 2015:[Epub aheaed of print] doi:10.1242/jcs.175018 Epub:
Yes Abstract:
Cyclin Dependent Kinase (CDK)9 acts via the Positive Transcription Elongation Factor-b (P-TEFb) complex to activate and expand... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Matrone G, Wilson KS, Maqsood S, Mullins JJ, Tucker CS, Denvir MA. CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart. J Cell Sci. 2015:[Epub aheaed of print] doi:10.1242/jcs.175018. |
The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3
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Citation:
Proc Natl Acad Sci U S A. 2015 Nov 4. pii: 201510495. [Epub ahead of print] Epub:
Yes Abstract:
Three genes, CCM1, CCM2, and CCM3, interact genetically and biochemically and are mutated in cerebral cavernous malformations (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cullere X, Plovie E, Bennett PM, MacRae CA, Mayadas TN. The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3. Proc Natl Acad Sci U S A. 2015 Nov 4. pii: 201510495. [Epub ahead of print]. |
Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of Left-Right asymmetry
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Citation:
Mol Biol Cell. 2015;[epub ahead of print] doi:10.1091/mbc.E15-07-0474 Epub:
Yes Abstract:
The establishment of Left-Right asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Silva E, Betleja E, John E, Spear P, Moresco JJ, Zhang S, Yates JR III, Mitchell BJ, Mahjoub MR. Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of Left-Right asymmetry. Mol Biol Cell. 2015;[epub ahead of print] doi:10.1091/mbc.E15-07-0474. |
Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213
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Citation:
Sci Rep. 2015;5:16161. doi:10.1038/srep16161 Epub:
Not Epub Abstract:
Mysterin (also known as RNF213) is a huge intracellular protein with two AAA+ ATPase modules and a RING finger ubiquitin ligase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kotani Y, Morito D, Yamazaki S, Ogino K, Kawakami K, Takashima S, Hirata H, Nagata K. Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213. Sci Rep. 2015;5:16161. doi:10.1038/srep16161. |
A human laterality disorder caused by a homozygous deleterious mutation in MMP21
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Citation:
J Med Genet. 2015 Oct 1. pii: jmedgenet-2015-103336. doi: 10.1136/jmedgenet-2015-103336. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Laterality in the vertebrate embryo is determined by left-right asymmetric gene expression driven by the flow of... Organism or Cell Type:
zebrafish Citation Extract: Perles Z, Moon S, Ta-Shma A, Yaacov B, Francescatto L, Edvardson S, Rein AJ, Elpeleg O, Katsanis N. A human laterality disorder caused by a homozygous deleterious mutation in MMP21. J Med Genet. 2015 Oct 1. pii: jmedgenet-2015-103336. doi: 10.1136/jmedgenet-2015-103336. [Epub ahead of print]. |
Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome
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Citation:
Hum Mol Genet. 2015 Sep 18. pii: ddv388. [Epub ahead of print] Epub:
Yes Abstract:
SPOAN syndrome is a neurodegenerative disorder mainly characterized by spastic paraplegia, optic atrophy and neuropathy (SPOAN... Organism or Cell Type:
zebrafish Citation Extract: Melo US, Macedo-Souza LI, Figueiredo T, Muotri AR, Gleeson JG, Coux G, Armas P, Calcaterra NB, Kitajima JP, Amorim S, Olávio TR, Griesi-Oliveira K, Coatti GC, Rocha CR, Martins-Pinheiro M, Menck CF, Zaki MS, Kok F, Zatz M, Santos S. Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome. Hum Mol Genet. 2015 Sep 18. pii: ddv388. [Epub ahead of print]. |