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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway
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Citation:
J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23 Epub:
Not Epub Abstract:
The non-canonical WNT/planar cell polarity (WNT/PCP) pathway plays important roles in morphogenetic processes in vertebrates.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Martinez S, Scerbo P, Giordano M, Daulat AM, Lhoumeau AC, Thomé V, Kodjabachian L, Borg JP. The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway. J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23. |
Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD)
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Citation:
Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124 Epub:
Not Epub Abstract:
Eteplirsen, SRP-4045 and SRP-4053 are three PMOs developed as treatments for DMD. DMD is mostly caused by mutations in the... Delivery Method:
iv infusion Organism or Cell Type:
Nonhuman primate, human Citation Extract: Sazani P, Magee T, Charleston JS, Shanks C, Zhang J, Carver M, Rodino-Klapac L, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Malik V, Shontz K, Flanigan K, Shilling C, Bhalli J, Kaur H, Walisser J, Forget J, Saoud J, Mendell JR, Kaye E
. Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD). Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124. |
Venous-derived angioblasts generate organ-specific vessels during zebrafish embryonic development
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Citation:
Development. 2015 Dec 15;142(24):4266-78. doi: 10.1242/dev.129247. Epub 2015 Nov 2 Epub:
Not Epub Abstract:
Formation and remodeling of vascular beds are complex processes orchestrated by multiple signaling pathways. Although it is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hen G, Nicenboim J, Mayseless O, Asaf L, Shin M, Busolin G, Hofi R, Almog G, Tiso N, Lawson ND, Yaniv K. Venous-derived angioblasts generate organ-specific vessels during zebrafish embryonic development. Development. 2015 Dec 15;142(24):4266-78. doi: 10.1242/dev.129247. Epub 2015 Nov 2. |
Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal
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Citation:
Development. 2015 Dec 15;142(24):4329-39. doi: 10.1242/dev.124750. Epub 2015 Nov 2 Epub:
Not Epub Abstract:
Tbx5 plays a pivotal role in vertebrate forelimb initiation, and loss-of-function experiments result in deformed or absent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mao Q, Stinnett HK, Ho RK. Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal. Development. 2015 Dec 15;142(24):4329-39. doi: 10.1242/dev.124750. Epub 2015 Nov 2. |
Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca 2+signaling during myogenesis in intact zebrafish
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Citation:
Int J Dev Biol. 2015;59(7-8-9):313-325 Epub:
Not Epub Abstract:
We have recently characterized essential inositol 1,4,5-trisphosphate receptor (IP 3R) and ryanodine receptor (RyR)-mediated Ca... Organism or Cell Type:
zebrafish Citation Extract: Kelu JJ, Chan HL, Webb SE, Cheng AH, Ruas M, Parrington J, Galione A, Miller AL. Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca 2+signaling during myogenesis in intact zebrafish. Int J Dev Biol. 2015;59(7-8-9):313-325. |
Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio)
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Citation:
Mol Cell Endocrinol. 2015 Dec 8. pii: S0303-7207(15)30156-8. doi: 10.1016/j.mce.2015.12.001. [Epub ahead of print] Epub:
Yes Abstract:
In mammals, sodium/hydrogen exchanger (NHE) and sodium-chloride cotransporter (NCC) are expressed in renal tubules, and exhibit... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin CH, Hu HJ, Hwang PP. Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio). Mol Cell Endocrinol. 2015 Dec 8. pii: S0303-7207(15)30156-8. doi: 10.1016/j.mce.2015.12.001. [Epub ahead of print]. |
Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development
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Citation:
Angiogenesis. 2015 Dec 17. [Epub ahead of print] doi:10.1007/s10456-015-9492-3 Epub:
Yes Abstract:
In the adult, new vessels and red blood cells form in response to hypoxia. Here, the oxygen-sensing system (PHD-HIF) has... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Metikala S, Neuhaus H, Hollemann T. Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development. Angiogenesis. 2015 Dec 17. [Epub ahead of print] doi:10.1007/s10456-015-9492-3. |
The water channel aquaporin-1a1 facilitates movement of CO2 and ammonia in zebrafish (Danio rerio) larvae
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Citation:
J Exp Biol. 2015 Dec;218(Pt 24):3931-40. doi: 10.1242/jeb.129759 Epub:
Not Epub Abstract:
The present study tested the hypothesis that zebrafish (Danio rerio) aquaporin-1a1 (AQP1a1) serves as a multi-functional... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Talbot K, Kwong RW, Gilmour KM, Perry SF. The water channel aquaporin-1a1 facilitates movement of CO2 and ammonia in zebrafish (Danio rerio) larvae. J Exp Biol. 2015 Dec;218(Pt 24):3931-40. doi: 10.1242/jeb.129759. |
Metabolic regulation of the ultradian oscillator Hes1 by reactive oxygen species
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Citation:
J Mol Biol. 2015 May 22;427(10):1887-902. doi: 10.1016/j.jmb.2015.03.007. Epub 2015 Mar 18 Epub:
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Ultradian oscillators are cyclically expressed genes with a period of less than 24h, found in the major signalling pathways.... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Ventre S, Indrieri A, Fracassi C, Franco B, Conte I, Cardone L, di Bernardo D. Metabolic regulation of the ultradian oscillator Hes1 by reactive oxygen species. J Mol Biol. 2015 May 22;427(10):1887-902. doi: 10.1016/j.jmb.2015.03.007. Epub 2015 Mar 18. |
A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes
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Citation:
Elife. 2015 Dec 15;4. pii: e11147. doi: 10.7554/eLife.11147. [Epub ahead of print] Epub:
Not Epub Abstract:
Electron microscopy-based connectomics aims to comprehensively map synaptic connections in neural tissue. However, current... Delivery Method:
microinjection Organism or Cell Type:
Platynereis dumerilii Citation Extract: Shahidi R, Williams EA, Conzelmann M, Asadulina A, Verasztó C, Jasek S, Bezares-Calderón LA, Jékely G. A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes. Elife. 2015 Dec 15;4. pii: e11147. doi: 10.7554/eLife.11147. [Epub ahead of print]. |