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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior

Authors:
Venturini V, Pezzano F, Castro FC, Häkkinen H-M, Jiménez-Delgado S, Colomer-Rosell M, Marro M, Tolosa-Ramon Q, Paz-López S, Valverde MA, Weghuber J, Loza-Alvarez P, Krieg M, Wieser S, Ruprecht V
Citation:
Science. 2020;370(6514) [Epub ahead of print] doi:10.1126/science.aba2644
Epub:
Yes
Abstract:
The physical microenvironment regulates cell behavior during tissue development and homeostasis. How single cells decode...
Organism or Cell Type:
zebrafish
Citation Extract:
Venturini V, Pezzano F, Castro FC, Häkkinen H-M, Jiménez-Delgado S, Colomer-Rosell M, Marro M, Tolosa-Ramon Q, Paz-López S, Valverde MA, Weghuber J, Loza-Alvarez P, Krieg M, Wieser S, Ruprecht V. The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior. Science. 2020;370(6514) [Epub ahead of print] doi:10.1126/science.aba2644.

Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons

Authors:
Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW
Citation:
J Neurosci. 2020 Oct 28;40(44):8463-8477. doi: 10.1523/JNEUROSCI.2666-19.2020. Epub 2020 Oct 13. PMID: 33051346; PMCID: PMC7605418
Epub:
Yes
Abstract:
Relapse to drug use can be initiated by drug-associated cues. The intensity of cue-induced drug seeking in rodent models...
Delivery Method:
catheter to brain nucleus accumbans core (NAcore)
Organism or Cell Type:
Rat
Citation Extract:
Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW . Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons. J Neurosci. 2020 Oct 28;40(44):8463-8477. doi: 10.1523/JNEUROSCI.2666-19.2020. Epub 2020 Oct 13. PMID: 33051346; PMCID: PMC7605418.

Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer

Authors:
Li Y, Gao X, Wei C, Guo R, Xu H, Bai Z, Zhou J, Zhu J, Wang W, Wu Y, Li J, Zhang Z, Xie X
Citation:
Aging. 2020;12. doi:10.18632/aging.103766
Epub:
Not Epub
Abstract:
Splicing dysregulation, which leads to apoptosis resistance, has been recognized as a major hallmark for tumorigenesis and...
Delivery Method:
Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
cell culture: gastric cancer lines MKN-28, SGC-7901, and MKN-45; xenograft mice
Citation Extract:
Li Y, Gao X, Wei C, Guo R, Xu H, Bai Z, Zhou J, Zhu J, Wang W, Wu Y, Li J, Zhang Z, Xie X. Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer. Aging. 2020;12. doi:10.18632/aging.103766.

Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1

Authors:
Ichikawa T, Stuckenholz C, Davidson LA
Citation:
Sci Rep. 2020;10:17326. doi:10.1038/s41598-020-73862-y
Epub:
Not Epub
Abstract:
Classical cadherins are well-known adhesion molecules responsible for physically connecting neighboring cells and signaling...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1. Sci Rep. 2020;10:17326. doi:10.1038/s41598-020-73862-y.

β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors

Authors:
Nishiwaki Y, Masai I
Citation:
Sci Rep. 2020;10:17379. doi:10.1038/s41598-020-74360-x
Epub:
Not Epub
Abstract:
BNip1, which functions as a t-SNARE component of the syntaxin18 complex, is localized on the ER membrane and regulates...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishiwaki Y, Masai I. β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors. Sci Rep. 2020;10:17379. doi:10.1038/s41598-020-74360-x.

Zebrafish hhatla is involved in cardiac hypertrophy

Authors:
Shi X, Zhang Y, Gong Y, Chen M, Brand‐Arzamendi K, Liu X, Wen X-Y
Citation:
J Cell Physiol. 2020;[Epub ahead of print] doi:10.1002/jcp.30106
Epub:
Yes
Abstract:
Cardiac hypertrophy is a compensatory response to pathological stimuli, ultimately progresses to cardiomyopathy, heart failure...
Organism or Cell Type:
zebrafish
Citation Extract:
Shi X, Zhang Y, Gong Y, Chen M, Brand‐Arzamendi K, Liu X, Wen X-Y. Zebrafish hhatla is involved in cardiac hypertrophy. J Cell Physiol. 2020;[Epub ahead of print] doi:10.1002/jcp.30106.

Identification and characterisation of highly fluorescent pigment cells in embryos of the Arabian killifish (Aphanius dispar)

Authors:
Hamied A, Alnedawy Q, Correia A, Hacker C, Ramsdale M, Hashimoto H, Kudoh T
Citation:
iScience. 2020 Oct 13;23(11):101674. doi: 10.1016/j.isci.2020.101674. eCollection 2020 Nov 20.
Epub:
Not Epub
Abstract:
The Arabian Killifish, Aphanius dispar, is a small tropical teleost fish living in wide range of habitats in sea water and...
Delivery Method:
microinjection
Organism or Cell Type:
Aphanius dispar (Arabian killifish)
Citation Extract:
Hamied A, Alnedawy Q, Correia A, Hacker C, Ramsdale M, Hashimoto H, Kudoh T. Identification and characterisation of highly fluorescent pigment cells in embryos of the Arabian killifish (Aphanius dispar). iScience. 2020 Oct 13;23(11):101674. doi: 10.1016/j.isci.2020.101674. eCollection 2020 Nov 20..

Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target

Authors:
Wei H, Xu Y, Wang Y,Liting Xu L, Mo C, Li L, Shen B, Sun Y, Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R
Citation:
Cell Rep. 2020;33(2):108252. doi:10.1016/j.celrep.2020.108252
Epub:
Not Epub
Abstract:
Osteogenic suppressors such as Sclerostin not only regulate skeletal development and regeneration but also serve as anti-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei H, Xu Y, Wang Y,Liting Xu L, Mo C, Li L, Shen B, Sun Y, Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R. Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target. Cell Rep. 2020;33(2):108252. doi:10.1016/j.celrep.2020.108252.

The slc4a2b gene is required for hair cell development in zebrafish

Authors:
Qian F, Wang X, Yin Z, Xie G, Yuan H, Liu D, Chai R
Citation:
Aging. 2020;[Epub] doi:10.18632/aging.103840
Epub:
Not Epub
Abstract:
Hair cells (HCs) function as important sensory receptors that can detect movement in their immediate environment. HCs in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qian F, Wang X, Yin Z, Xie G, Yuan H, Liu D, Chai R. The slc4a2b gene is required for hair cell development in zebrafish. Aging. 2020;[Epub] doi:10.18632/aging.103840.

Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network

Authors:
Arnold TR, Shawky JH, Stephenson RE, Dinshaw KM, Higashi T, Huq F, Davidson LA, Miller AL
Citation:
Elife. 2019 Jan 31;8:e39065. doi:10.7554/eLife.39065
Epub:
Not Epub
Abstract:
Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Arnold TR, Shawky JH, Stephenson RE, Dinshaw KM, Higashi T, Huq F, Davidson LA, Miller AL. Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network. Elife. 2019 Jan 31;8:e39065. doi:10.7554/eLife.39065.

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