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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Gene regulatory networks controlling vertebrate retinal regeneration
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Citation:
Science. 2020;360(6519):eabb8598 doi:10.1126/science.abb8598 Epub:
Not Epub Abstract:
Injury induces retinal Müller glia of certain cold-blooded vertebrates, but not mammals, to regenerate neurons. To identify... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Hoang T, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Yoo S, Lahne M, Todd LJ, Jia M, Saez C, Keuthan C, Palazzo I, Squires N, Campbell WA, Rajaii F, Parayil T, Trinh V, Kim DW, Wang G, Campbell LJ, Ash J, Fischer AJ, Hyde DR, Qian J, Blackshaw S. Gene regulatory networks controlling vertebrate retinal regeneration. Science. 2020;360(6519):eabb8598 doi:10.1126/science.abb8598. |
The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling
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Citation:
eLife. 2018:7:e38889 doi:10.7554/eLife.38889 Epub:
Not Epub Abstract:
Complex interplay between cardiac tissues is crucial for their integrity. The flow responsive transcription factor KLF2, which... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rasouli SJ, El-Brolosy M, Tsedeke AT, Bensimon-Brito A, Ghanbari P, Maischein H-M, Kuenne C, Stainier DY. The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling. eLife. 2018:7:e38889 doi:10.7554/eLife.38889. |
Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists
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Citation:
eLife. 2018;7:e42209. doi:10.7554/eLife.42209 Epub:
Not Epub Abstract:
Pathways modulating glucose homeostasis independently of insulin would open new avenues to combat insulin resistance and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mullapudi ST, Helker CSM, Boezio GLM, Maischein H-M, Sokol AM, Guenther S, Matsuda H, Kubicek S, Graumann J, Yang YSC, Stainier DYR. Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists. eLife. 2018;7:e42209. doi:10.7554/eLife.42209. |
Differential gene expression of virulence factors modulates infectivity of TcI Trypanosoma cruzi strains
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Citation:
Parasitol Res. 2020 Oct 2. doi: 10.1007/s00436-020-06891-1. Online ahead of print Epub:
Yes Abstract:
Trypanosoma cruzi is the etiological agent of Chagas disease, whose clinical outcome ranges from asymptomatic individuals to... Organism or Cell Type:
Trypanosoma cruzi Citation Extract: Arroyo-Olarte RD, Martínez I, Lujan E, Mendlovic F, Dinkova T, Espinoza B. Differential gene expression of virulence factors modulates infectivity of TcI Trypanosoma cruzi strains. Parasitol Res. 2020 Oct 2. doi: 10.1007/s00436-020-06891-1. Online ahead of print. |
The low affinity p75 neurotrophin receptor is down-regulated in congenital anomalies of the kidney and the urinary tract: Possible involvement in early nephrogenesis
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Citation:
Biochem Biophys Res Commun. 2020 Sep 25:S0006-291X(20)31831-3. doi: 10.1016/j.bbrc.2020.09.084 Epub:
Not Epub Abstract:
Congenital Anomalies of the Kidney and of the Urinary Tract (CAKUT) cover a broad range of disorders including abnormal kidney... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fédou C, Lescat O, Feuillet G, Buléon M, Neau E, Breuil B, Alvès M, Batut J, Blader P, Decramer S, Saulnier-Blache JS, Klein J, Buffin-Meyer B, Schanstra JP. The low affinity p75 neurotrophin receptor is down-regulated in congenital anomalies of the kidney and the urinary tract: Possible involvement in early nephrogenesis. Biochem Biophys Res Commun. 2020 Sep 25:S0006-291X(20)31831-3. doi: 10.1016/j.bbrc.2020.09.084. |
A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson’s Disease Arising from Parkin Mutations
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Citation:
Int J Mol Sci. 2020;21(19):7282. doi:10.3390/ijms21197282 Epub:
Not Epub Abstract:
Parkin-type autosomal recessive juvenile-onset Parkinson’s disease is caused by mutations in the PRKN gene and accounts for 50... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: PRKN patient-derived fibroblasts Citation Extract: Li D, Aung-Htut MT, Ham KA, Fletcher S, Wilton SD. A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson’s Disease Arising from Parkin Mutations. Int J Mol Sci. 2020;21(19):7282. doi:10.3390/ijms21197282. |
Beta-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism
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Citation:
Cancer Res. 2020;[Epub] doi:10.1158/0008-5472.CAN-19-3382 Epub:
Not Epub Abstract:
Disturbance of sphingolipid metabolism may represent a novel therapeutic target in metastatic melanoma, the most lethal form of... Organism or Cell Type:
zebrafish Citation Extract: Belleri M, Paganini G, Coltrini D, Ronca R, Zizioli D, Corsini M, Barbieri A, Grillo E, Calza S, Bresciani R, Maiorano E, Mastropasqua MG, Annese T, Giacomini A, Ribatti D, Casas J, Levade T, Fabrias G, Presta M. Beta-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism. Cancer Res. 2020;[Epub] doi:10.1158/0008-5472.CAN-19-3382. |
Hmx3a has essential functions in zebrafish spinal cord, ear and lateral line development
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Citation:
bioRxiv 2020.01.23.917468; doi: https://doi.org/10.1101/2020.01.23.917468 Epub:
Not Epub Abstract:
Transcription factors that contain a homeodomain DNA-binding domain have crucial functions in most aspects of cellular function... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: England SJ, Cerda GA, Kowalchuk AM, Sorice T, Grieb GM, Lewis KE. Hmx3a has essential functions in zebrafish spinal cord, ear and lateral line development. bioRxiv 2020.01.23.917468; doi: https://doi.org/10.1101/2020.01.23.917468 . |
Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces
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Citation:
Neuroscience. 2020;[Epub ahead of print] doi:10.1016/j.neuroscience.2020.09.046 Epub:
Yes Abstract:
Growth cone - mediated axonal outgrowth and accurate synaptic targeting are central to brain morphogenesis. Translocation of... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) spinal cord explants Citation Extract: Ghate K, Mutalik SP, Sthanam LK, Sen S, Ghose A. Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces. Neuroscience. 2020;[Epub ahead of print] doi:10.1016/j.neuroscience.2020.09.046. |
VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
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Citation:
J Biol Chem. 2020;[Epub ahead of print] doi:10.1074/jbc.RA120.015282 Epub:
Yes Abstract:
The Wnt/β-catenin pathway is one of the major pathways that regulates embryonic development, adult homeostasis, and stem cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang H, Rong X, Wang C, Liu Y, Lu L, Li Y, Zhao C, Zhou J. VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs. J Biol Chem. 2020;[Epub ahead of print] doi:10.1074/jbc.RA120.015282. |