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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites
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Citation:
Elife. 2019 Mar 11;8:e42455. doi:10.7554/eLife.42455 Epub:
Not Epub Abstract:
Interactions between epithelial cells and neurons influence a range of sensory modalities including taste, touch, and smell.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiang N, Rasmussen JP, Clanton JA, Rosenberg MF, Luedke KP, Cronan MR, Parker ED, Kim HJ, Vaughan JC, Sagasti A, Parrish JZ. A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites. Elife. 2019 Mar 11;8:e42455. doi:10.7554/eLife.42455. |
Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis
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Citation:
Elife. 2018 Dec 6;7:e40556. doi:10.7554/eLife.40556 Epub:
Not Epub Abstract:
A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Bhattacharya D, Rothstein M, Azambuja AP, Simoes-Costa M. Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis. Elife. 2018 Dec 6;7:e40556. doi:10.7554/eLife.40556. |
Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.18.344523 Epub:
Not Epub Abstract:
Epithelial-to-mesenchymal transition (EMT) is a dramatic change in cellular physiology during development and metastasis which... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Piacentino ML, Hutchins EJ, Andrews CJ, Bronner ME. Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.18.344523 . |
Morpholino-Mediated Knockdown of Ciliary Genes in Euplotes vannus, a Novel Marine Ciliated Model Organism
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Citation:
Front Microbiol. 2020;11:254 doi:10.3389/fmicb.2020.549781 Epub:
Not Epub Abstract:
Cilia are highly conserved organelles present in almost all types of eukaryotic cells, and defects in cilia structure and/or... Delivery Method:
microinjection Organism or Cell Type:
Euplotes vannus (ciliate) Citation Extract: Tang D, Wang X, Dong J, Li Y, Gao F, Xie H, Zhao C. Morpholino-Mediated Knockdown of Ciliary Genes in Euplotes vannus, a Novel Marine Ciliated Model Organism. Front Microbiol. 2020;11:254 doi:10.3389/fmicb.2020.549781 . |
Nonsequential Splicing Events Alter Antisense-Mediated Exon Skipping Outcome in COL7A1
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Citation:
Int J Molec Sci. 2020;21(20):1422-0067 doi:10.3390/ijms21207705 Epub:
Not Epub Abstract:
The COL7A1 gene encodes homotrimer fibrils essential for anchoring dermal and epidermal layers, and pathogenic mutations in... Delivery Method:
electroporation Organism or Cell Type:
cell culture: primary human dermal fibroblasts Citation Extract: Ham KA, Aung-Htut MT, Fletcher D, Wilton SD. Nonsequential Splicing Events Alter Antisense-Mediated Exon Skipping Outcome in COL7A1. Int J Molec Sci. 2020;21(20):1422-0067 doi:10.3390/ijms21207705. |
Collective cancer cell invasion requires RNA accumulation at the invasive front
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Citation:
Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2010872117 Epub:
Yes Abstract:
Localization of RNAs at protrusive regions of cells is important for single-cell migration on two-dimensional surfaces.... Delivery Method:
Endo-Porter or Vivo-Morpholino Organism or Cell Type:
cell culture: MDA-MB-231 Citation Extract: Chrisafis G, Wang T, Moissoglu K, Gasparski AN, Ng Y, Weigert R, Lockett SJ, Mili S. Collective cancer cell invasion requires RNA accumulation at the invasive front. Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2010872117 . |
Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation
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Citation:
JCI Insight. 2020;5(20):e133019. doi:10.1172/jci.insight.133019 Epub:
Not Epub Abstract:
Although congenital heart defects (CHDs) represent the most common birth defect, a comprehensive understanding of disease... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu P-N, Moreland T, Christian CJ, Lund TC, Steet RA, Flanagan-Steet H. Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation. JCI Insight. 2020;5(20):e133019. doi:10.1172/jci.insight.133019. |
Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom
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Citation:
Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2011120117 Epub:
Yes Abstract:
The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model for characterizing the evolution of genes... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (cniderian) Citation Extract: Sachkova MY, Landau M, Surm JM, Macrander J, Singer SA, Reitzel AM, Moran Y. Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom. Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2011120117. |
Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish
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Citation:
PLoS ONE. 2020;15(10):e0240129. doi:10.1371/journal.pone.0240129 Epub:
Not Epub Abstract:
We examined a patient and her older brother who both presented with complicated severe hypertrophic cardiomyopathy (HCM) and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Okamoto R, Goto I,Nishimura Y, Kobayashi I, Hashizume R, Yoshida Y, Ito R, Kobayashi Y, Nishikawa M, Ali Y, Saito S, Tanaka T, Sawa Y, Ito M, Dohi K. Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish. PLoS ONE. 2020;15(10):e0240129. doi:10.1371/journal.pone.0240129. |
Respiratory responses to external ammonia in zebrafish (Danio rerio)
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Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2020;[Epub] doi:10.1016/j.cbpa.2020.110822 Epub:
Yes Abstract:
The effects of high external ammonia (HEA) exposure on breathing and the potential involvement of ammonia transporting Rh... Organism or Cell Type:
zebrafish Citation Extract: Porteus C, Kumai Y, Abdallah SJ, Yew HM, Kwong RWM, Pan Y, Milsom WK, Perry SF. Respiratory responses to external ammonia in zebrafish (Danio rerio). Comp Biochem Physiol A Mol Integr Physiol. 2020;[Epub] doi:10.1016/j.cbpa.2020.110822. |