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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.20.347385 Epub:
Not Epub Abstract:
First described in Drosophila melanogaster, planar cell polarity (PCP) is a developmental process essential for embryogenesis... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Walton A, Revinski D, Serge A, Audebert S, Camoin L, Puvirajesinghe TM, Isnardon D, Marchetto S, Kodjabachian L, Bailly E, Borg J-P. A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.20.347385 . |
Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans
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Citation:
Diagnostics. 2020;10(10):854 doi:10.3390/diagnostics10100854 Epub:
Not Epub Abstract:
Mucopolysaccharidosis type II (MPS II) is an X-linked disorder resulting from a deficiency in iduronate 2-sulfatase (IDS),... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin C-Y, Lin H-Y, Chuang C-K, Zhang P-H, Tu 4 R-Y, Lin S-P, Tsai H-J. Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans. Diagnostics. 2020;10(10):854 doi:10.3390/diagnostics10100854. |
The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models
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Citation:
Nat Comm. 2020;11(1):5319. doi:10.1038/s41467-020-19008-0 Epub:
Not Epub Abstract:
Arterial networks enlarge in response to increase in tissue metabolism to facilitate flow and nutrient delivery. Typically, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Klems A, van Rijssel J, Ramms AS, Wild R, Hammer J, Merkel M, Derenbach L, Préau L, Hinkel R, Suarez-Martinez I, Schulte-Merker S, Vidal R, Sauer S, Kivelä R, Alitalo K, Kupatt C, van Buul JD, le Noble F. The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nat Comm. 2020;11(1):5319. doi:10.1038/s41467-020-19008-0. |
Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish
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Citation:
Open Biol. 2020 Oct;10(10):200281. doi: 10.1098/rsob.200281. Epub 2020 Oct 21 Epub:
Not Epub Abstract:
Angiogenesis is a precise process mediated by a variety of signals and the environmental niche. Although the essential trace... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xia Z, Bi X, Lian J, Dai W, He X, Zhao L, Min J, Wang F. Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish. Open Biol. 2020 Oct;10(10):200281. doi: 10.1098/rsob.200281. Epub 2020 Oct 21. |
Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy
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Citation:
Histochem Cell Biol. 2020 Oct 20. doi: 10.1007/s00418-020-01925-2. Online ahead of print Epub:
Yes Abstract:
Lysosomal storage diseases are the most common cause of neurodegeneration in children. They are characterised at the cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cook SR, Bladen C, Smith J, Maguire E, Copner J, Fenn GD, Wager K, Waller-Evans H, Lloyd-Evans E. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochem Cell Biol. 2020 Oct 20. doi: 10.1007/s00418-020-01925-2. Online ahead of print. |
Unravelling the disease mechanism for TSPYL1 deficiency
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Citation:
Hum Mol Genet. 2020;[Epub aheaed of print] doi:10.1093/hmg/ddaa233 Epub:
Yes Abstract:
We describe a lethal combined nervous and reproductive systems disease in three affected siblings of a consanguineous family.... Organism or Cell Type:
zebrafish Citation Extract: Buyse G, Di Michele M, Wijgaerts A, Louwette S, Wittevrongel C, Thys C, Downes K, Ceulemans B, Van Esch H, Van Geet C, Freson K. Unravelling the disease mechanism for TSPYL1 deficiency. Hum Mol Genet. 2020;[Epub aheaed of print] doi:10.1093/hmg/ddaa233. |
setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals
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Citation:
Cell Discov. 2020;6(1):72 doi:10.1038/s41421-020-00203-8 Epub:
Not Epub Abstract:
Setd2 is the only enzyme that catalyzes histone H3 lysine 36 trimethylation (H3K36me3) on virtually all actively transcribed... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu D-J, Zhang F, Chen Y, Jin Y, Zhang Y-L, Chen S-B, Xie Y-Y, Huang Q-H, Zhao W-L, Wang L, Xu P-F, Chen Z, Chen S-J, Li B, Zhang A, Sun X-J. setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals. Cell Discov. 2020;6(1):72 doi:10.1038/s41421-020-00203-8. |
Hmx3a Has Essential Functions in Zebrafish Spinal Cord, Ear and Lateral Line Development
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Citation:
Genetics. 2020;[Epub ahead of print] doi:10.1534/genetics.120.303748 Epub:
Yes Abstract:
Transcription factors that contain a homeodomain DNA-binding domain have crucial functions in most aspects of cellular function... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: England SJ, Cerda GA, Kowalchuk A, Sorice T, Grieb G, Lewis KE. Hmx3a Has Essential Functions in Zebrafish Spinal Cord, Ear and Lateral Line Development. Genetics. 2020;[Epub ahead of print] doi:10.1534/genetics.120.303748. |
The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
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Citation:
Cell Rep. 2020;33(3):108295. doi:10.1016/j.celrep.2020.108295 Epub:
Not Epub Abstract:
TMEM18 is the strongest candidate for childhood obesity identified from GWASs, yet as for most GWAS-derived obesity-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Landgraf K, Klöting N, Gericke M, Maixner N, Guiu-Jurado E, Scholz M, Witte AV, Beyer F, Schwartze JT, Lacher M, Villringer A, Kovacs P, Rudich A, Blüher M, Kiess W, Körner A. The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG. Cell Rep. 2020;33(3):108295. doi:10.1016/j.celrep.2020.108295. |
AIBP-CAV1-VEGFR3 axis dictates lymphatic cell fate and controls lymphangiogenesis
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.16.342998 Epub:
Not Epub Abstract:
The lymphatics are essential for the maintenance of tissue fluid homeostasis. Accordingly, lymphatic dysfunction contributes to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang X, Kim J, Gu Q, Yan Q, Astin J, Crosier P, Yu P, Rockson SG, Fang L. AIBP-CAV1-VEGFR3 axis dictates lymphatic cell fate and controls lymphangiogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.16.342998. |