You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Pcdh18a-positive tip cells instruct notochord formation in zebrafish

Authors:
Bosze B, Mattes B, Sinner C, Stricker K, Gourain V, Thumberger T, Tlili S, Weber S, Wittbrodt J, Saunders TE, Strähle U, Schug A, Scholpp S
Citation:
bioRxiv. 2018;[preprint] doi:10.1101/257717
Epub:
Not Epub
Abstract:
The notochord defines the axial structure of all vertebrates during development. Notogenesis is a result of major cell...
Link:
https://www.biorxiv.org/content/10.1101/257717v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bosze B, Mattes B, Sinner C, Stricker K, Gourain V, Thumberger T, Tlili S, Weber S, Wittbrodt J, Saunders TE, Strähle U, Schug A, Scholpp S. Pcdh18a-positive tip cells instruct notochord formation in zebrafish. bioRxiv. 2018;[preprint] doi:10.1101/257717.

RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

Authors:
Farooq M, Lindbæk L, Krogh N, Doganli C, Keller C, Mönnich M, Gonçalves AB, Sakthivel S, Mang Y, Fatima A, Andersen VS, Hussain MS, Eiberg H, Hansen L, Kjaer KW, Gopalakrishnan J, Pedersen LB, Møllgård K, Nielsen H, Baig SM, Tommerup N, Christensen ST, Larsen LA
Citation:
Nat Commun. 2020;11:5816 doi:10.1038/s41467-020-19658-0
Epub:
Not Epub
Abstract:
Primary microcephaly (MCPH) is characterized by reduced brain size and intellectual disability. The exact pathophysiological...
Link:
https://www.nature.com/articles/s41467-020-19658-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Farooq M, Lindbæk L, Krogh N, Doganli C, Keller C, Mönnich M, Gonçalves AB, Sakthivel S, Mang Y, Fatima A, Andersen VS, Hussain MS, Eiberg H, Hansen L, Kjaer KW, Gopalakrishnan J, Pedersen LB, Møllgård K, Nielsen H, Baig SM, Tommerup N, Christensen ST, Larsen LA. RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis. Nat Commun. 2020;11:5816 doi:10.1038/s41467-020-19658-0.

Investigating the effect of DMD non-sequential splicing on exon skipping strategies

Authors:
Goossens R, Verwey N, Schnell F, Aartsma-Rus A
Citation:
Neuromuscul Disord. 2020;30(Suppl 1):S128-S129. P.281 doi:10.1016/j.nmd.2020.08.278
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy is one of the most common myopathies, with an incidence of 1:5000 in new-born boys. The root cause...
Link:
https://www.nmd-journal.com/article/S0960-8966(20)30475-2/fulltext
Organism or Cell Type:
cell culture: myocytes
Citation Extract:
Goossens R, Verwey N, Schnell F, Aartsma-Rus A. Investigating the effect of DMD non-sequential splicing on exon skipping strategies. Neuromuscul Disord. 2020;30(Suppl 1):S128-S129. P.281 doi:10.1016/j.nmd.2020.08.278.

Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.

Authors:
Cui J, Chen G, Wen D, Wang Y, Zhao Z, Wu C
Citation:
Front Cell Infect Microbiol. 2020 Oct 29;10:519503. doi: 10.3389/fcimb.2020.519503
Epub:
Not Epub
Abstract:
The ADP ribosylation factor (ARF) GTPase activation protein ASAP1 possesses multiple biological functions, including regulation...
Link:
https://www.frontiersin.org/articles/10.3389/fcimb.2020.519503/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cui J, Chen G, Wen D, Wang Y, Zhao Z, Wu C. Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.. Front Cell Infect Microbiol. 2020 Oct 29;10:519503. doi: 10.3389/fcimb.2020.519503.

The Caudal ParaHox gene is required for hindgut development in the mollusc Tritia (a.k.a. Ilyanassa)

Authors:
Johnson AB, Lambert JD
Citation:
Dev Biol. 2020 Oct 24;470:1-9. doi: 10.1016/j.ydbio.2020.10.010. Online ahead of print
Epub:
Not Epub
Abstract:
Caudal homeobox genes are found across animals, typically linked to two other homeobox genes in what has been called the...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160620302815
Organism or Cell Type:
Tritia obsoleta (previously Ilyanassa obsoleta) gastropod
Citation Extract:
Johnson AB, Lambert JD. The Caudal ParaHox gene is required for hindgut development in the mollusc Tritia (a.k.a. Ilyanassa). Dev Biol. 2020 Oct 24;470:1-9. doi: 10.1016/j.ydbio.2020.10.010. Online ahead of print.

Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells

Authors:
Kramerov AA, Shah R, Ding H, Holler E, Turjman S, Rabinowitz YS, Ghiam S, Maguen E, Svendsen CN, Saghizadeh M, Ljubimova JY, Ljubimov AV
Citation:
Nanomedicine. 2020;[Epub] doi:10.1016/j.nano.2020.102332
Epub:
Not Epub
Abstract:
Human diabetic corneas develop delayed wound healing, epithelial stem cell dysfunction, recurrent erosions, and keratitis....
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1549963420301866
Delivery Method:
nanopolymer
Organism or Cell Type:
cell culture: diabetic limbal epithelial cells; organ culture: cornea
Citation Extract:
Kramerov AA, Shah R, Ding H, Holler E, Turjman S, Rabinowitz YS, Ghiam S, Maguen E, Svendsen CN, Saghizadeh M, Ljubimova JY, Ljubimov AV. Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells. Nanomedicine. 2020;[Epub] doi:10.1016/j.nano.2020.102332.

The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina

Authors:
Toulis V, García-Monclús S, de la Peña-Ramírez C, Arenas-Galnares R, Abril JF, Todi SV, Khan N, Garanto A, Costa MDC, Marfany G
Citation:
Cell Rep. 2020 Nov 10;33(6):108360. doi: 10.1016/j.celrep.2020.108360
Epub:
Not Epub
Abstract:
Expansion of a CAG repeat in ATXN3 causes the dominant polyglutamine disease spinocerebellar ataxia type 3 (SCA3), yet the...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31349-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toulis V, García-Monclús S, de la Peña-Ramírez C, Arenas-Galnares R, Abril JF, Todi SV, Khan N, Garanto A, Costa MDC, Marfany G. The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina. Cell Rep. 2020 Nov 10;33(6):108360. doi: 10.1016/j.celrep.2020.108360.

Ppargc1a Controls Ciliated Cell Development by Regulating Prostaglandin Biosynthesis

Authors:
Chambers JM, Addiego A, Flores-Mireles AL, Wingert RA
Citation:
Cell Rep. 2020;22(6):108370. doi:10.1016/j.celrep.2020.108370
Epub:
Not Epub
Abstract:
Cilia are microtubule-based organelles that function in a multitude of physiological contexts to perform chemosensing,...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31359-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers JM, Addiego A, Flores-Mireles AL, Wingert RA. Ppargc1a Controls Ciliated Cell Development by Regulating Prostaglandin Biosynthesis. Cell Rep. 2020;22(6):108370. doi:10.1016/j.celrep.2020.108370.

AML poor prognosis factor, TPD52, is associated with the maintenance of haematopoietic stem cells through regulation of cell proliferation

Authors:
Kang JW, Kim Y, Lee Y, Myung K, Kim YH, Oh CK
Citation:
J Cell Biochem. 2020 Nov 9. doi: 10.1002/jcb.29869. Online ahead of print
Epub:
Yes
Abstract:
Acute myeloid leukaemia (AML) is a blood cancer where undifferentiated myeloid cells are increased in the bone marrow and...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.29869
Organism or Cell Type:
zebrafish
Citation Extract:
Kang JW, Kim Y, Lee Y, Myung K, Kim YH, Oh CK. AML poor prognosis factor, TPD52, is associated with the maintenance of haematopoietic stem cells through regulation of cell proliferation. J Cell Biochem. 2020 Nov 9. doi: 10.1002/jcb.29869. Online ahead of print.

A genetic modifier of venous thrombosis in zebrafish reveals a functional role for fibrinogen AαE in early hemostasis

Authors:
Freire C, Fish RJ, Vilar R, Di Sanza C, Grzegorski SJ, Richter CE, Shavit JA, Neerman-Arbez M
Citation:
Blood Adv. 2020;4(21):5480–5491. doi:10.1182/bloodadvances.2020001472
Epub:
Not Epub
Abstract:
Plasma fibrinogen molecules comprise 2 copies of Aα, Bβ, and γ chains folded into a hexameric protein. A minor fibrinogen...
Link:
https://ashpublications.org/bloodadvances/article/4/21/5480/474105/A-genetic-modifier-of-venous-thrombosis-in
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Freire C, Fish RJ, Vilar R, Di Sanza C, Grzegorski SJ, Richter CE, Shavit JA, Neerman-Arbez M. A genetic modifier of venous thrombosis in zebrafish reveals a functional role for fibrinogen AαE in early hemostasis. Blood Adv. 2020;4(21):5480–5491. doi:10.1182/bloodadvances.2020001472.

Pages