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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Continuous addition of progenitors forms the cardiac ventricle in zebrafish

Authors:
Felker A, Prummel KD, Merks AM, Mickoleit M, Brombacher EC, Huisken J, Panáková D, Mosimann C
Citation:
Nat Commun. 2018 May 21;9(1):2001. doi: 10.1038/s41467-018-04402-6
Epub:
Not Epub
Abstract:
The vertebrate heart develops from several progenitor lineages. After early-differentiating first heart field (FHF) progenitors...
Link:
https://www.nature.com/articles/s41467-018-04402-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Felker A, Prummel KD, Merks AM, Mickoleit M, Brombacher EC, Huisken J, Panáková D, Mosimann C. Continuous addition of progenitors forms the cardiac ventricle in zebrafish. Nat Commun. 2018 May 21;9(1):2001. doi: 10.1038/s41467-018-04402-6.

Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation

Authors:
DuBuc TQ, Stephenson TB, Rock AQ, Martindale MQ
Citation:
Nat Commun. 2018 May 22;9(1):2007. doi: 10.1038/s41467-018-04184-x
Epub:
Not Epub
Abstract:
Hox gene transcription factors are important regulators of positional identity along the anterior-posterior axis in bilaterian...
Link:
https://www.nature.com/articles/s41467-018-04184-x
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
DuBuc TQ, Stephenson TB, Rock AQ, Martindale MQ. Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation. Nat Commun. 2018 May 22;9(1):2007. doi: 10.1038/s41467-018-04184-x.

miR-133 mediated regulation of the hedgehog pathway orchestrates embryo myogenesis

Authors:
Mok GF, Lozano-Velasco E, Maniou E, Viaut C, Moxon S, Wheeler G, Münsterberg A
Citation:
Development. 2018 May 25. pii: dev.159657. doi: 10.1242/dev.159657. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal myogenesis serves as a paradigm to investigate the molecular mechanisms underlying exquisitely regulated cell fate...
Link:
http://dev.biologists.org/content/early/2018/05/23/dev.159657.long
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Mok GF, Lozano-Velasco E, Maniou E, Viaut C, Moxon S, Wheeler G, Münsterberg A. miR-133 mediated regulation of the hedgehog pathway orchestrates embryo myogenesis. Development. 2018 May 25. pii: dev.159657. doi: 10.1242/dev.159657. [Epub ahead of print].

Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals

Authors:
Gentsch GE, Spruce T, Owens NDL, Smith JC
Citation:
BioRxiv. 2018. doi:10.1101/306803
Epub:
Not Epub
Abstract:
The ability of cells to respond to intercellular signals, and the repertoire of possible responses to those signals, is defined...
Link:
https://www.biorxiv.org/content/early/2018/04/23/306803
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals. BioRxiv. 2018. doi:10.1101/306803 .

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish

Authors:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN
Citation:
bioRxiv. 2018. doi:10.1101/308221
Epub:
Not Epub
Abstract:
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection....
Link:
https://www.biorxiv.org/content/early/2018/04/25/308221.full.pdf+html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN. Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish. bioRxiv. 2018. doi:10.1101/308221.

Japanese Encephalitis Virus Infected Microglial Cells Secrete Exosomes Containing let-7a/b that Facilitate Neuronal Damage via Caspase Activation

Authors:
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A
Citation:
bioRxiv. 2018. doi:10.1101/324715
Epub:
Not Epub
Abstract:
Extracellular microRNAs (miRNAs) are essential for the cell to cell communication in the healthy and diseased brain. MicroRNAs...
Link:
https://www.biorxiv.org/content/early/2018/05/17/324715
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
BALB/c mice pups
Citation Extract:
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A. Japanese Encephalitis Virus Infected Microglial Cells Secrete Exosomes Containing let-7a/b that Facilitate Neuronal Damage via Caspase Activation. bioRxiv. 2018. doi:10.1101/324715.

Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells

Authors:
Hsieh FC, Lu YF, Liau I, Chen CC, Cheng CM, Hsiao CD, Hwang SL
Citation:
Sci Rep. 2018 May 18;8(1):7856. doi: 10.1038/s41598-018-26110-3
Epub:
Not Epub
Abstract:
Sarcomeric signaling complexes are important to sustain proper sarcomere structure and function, however, the mechanisms...
Link:
https://www.nature.com/articles/s41598-018-26110-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsieh FC, Lu YF, Liau I, Chen CC, Cheng CM, Hsiao CD, Hwang SL. Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells. Sci Rep. 2018 May 18;8(1):7856. doi: 10.1038/s41598-018-26110-3.

Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides

Authors:
Vohtancev IP, Sherstyuk YV, Silnikov VN, Abramova TV
Citation:
Org Prep Proc Int. 2018;50(3):332-42. doi:10.1080/00304948.2018.1462063
Epub:
Not Epub
Abstract:
No abstract available.
Link:
https://www.tandfonline.com/doi/full/10.1080/00304948.2018.1462063
Citation Extract:
Vohtancev IP, Sherstyuk YV, Silnikov VN, Abramova TV. Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides. Org Prep Proc Int. 2018;50(3):332-42. doi:10.1080/00304948.2018.1462063.

Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation

Authors:
Houssin NS, Bharathan NK, Turner SD, Dickinson AJ
Citation:
Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29
Epub:
Not Epub
Abstract:
BACKGROUND: The buccopharyngeal membrane is a thin layer of cells covering the embryonic mouth. The perforation of this...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/dvdy.24470
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Houssin NS, Bharathan NK, Turner SD, Dickinson AJ. Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation. Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29.

Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening

Authors:
Shimo T, Tachibana K, Obika S
Citation:
PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018
Epub:
Not Epub
Abstract:
Splice-switching oligonucleotides (SSOs) that can modulate RNA splicing are used for the treatment of many genetic disorders....
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197373#pone.0197373.s006
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: RD
Citation Extract:
Shimo T, Tachibana K, Obika S. Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening. PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018.

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