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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis
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Citation:
eLife. 2018;7:e33800 doi: 10.7554/eLife.33800 Epub:
Not Epub Abstract:
Alveolar rhabdomyosarcoma is a pediatric soft-tissue sarcoma caused by PAX3/7-FOXO1 fusion oncogenes and is characterized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. eLife. 2018;7:e33800 doi: 10.7554/eLife.33800. |
The homeobox protein VentX reverts immune suppression in the tumor microenvironment
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Citation:
Nat Comm. 2018;9:2175. doi:10.1038/s41467-018-04567-0 Epub:
Not Epub Abstract:
Immune suppression in the tumor microenvironment (TME) is a central obstacle to effective immunotherapy. Tumor-associated... Delivery Method:
electroporation Organism or Cell Type:
cell culture: human tumor associated macrophages (TAM) or human primary monocytes Citation Extract: Le Y, Gao H, Bleday R, Zhu Z. The homeobox protein VentX reverts immune suppression in the tumor microenvironment. Nat Comm. 2018;9:2175. doi:10.1038/s41467-018-04567-0. |
The macrophage as a Trojan horse for antisense oligonucleotide delivery
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Citation:
Expert Opin Ther Targets. 2018 Jun 4. doi: 10.1080/14728222.2018.1482279. [Epub ahead of print] Epub:
Yes Abstract:
The gateway to the promised land of gene therapy has been obstructed by the problem of accurate and efficient delivery of... Citation Extract: Novak JS, Jaiswal JK, Partridge TA. The macrophage as a Trojan horse for antisense oligonucleotide delivery. Expert Opin Ther Targets. 2018 Jun 4. doi: 10.1080/14728222.2018.1482279. [Epub ahead of print]. |
Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
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Citation:
Nat Comm. 2018;9:2161. doi:10.1038/s41467-018-04566-1 Epub:
Not Epub Abstract:
Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Merks AM, Swinarski M, Meyer AM, Müller NV, Özcan I, Donat S, Burger A, Gilbert S, Mosimann C, Abdelilah-Seyfried S, Panáková D. Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity. Nat Comm. 2018;9:2161. doi:10.1038/s41467-018-04566-1. |
TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons
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Citation:
Dev Biol. 2018 Jun 1;438(1):57-68. doi: 10.1016/j.ydbio.2018.02.011. Epub 2018 Mar 23 Epub:
Not Epub Abstract:
During the development of the early spinal circuitry in zebrafish, spontaneous Ca2+ transients in the primary motor neurons (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kelu JJ, Webb SE, Galione A, Miller AL. TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons. Dev Biol. 2018 Jun 1;438(1):57-68. doi: 10.1016/j.ydbio.2018.02.011. Epub 2018 Mar 23. |
The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish
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Citation:
Development. 2018 May 17;145(10). pii: dev159210. doi: 10.1242/dev.159210 Epub:
Not Epub Abstract:
Cardiac trabeculation is a highly regulated process that starts with the delamination of compact layer cardiomyocytes. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lai JKH, Collins MM, Uribe V, Jiménez-Amilburu V, Günther S, Maischein HM, Stainier DYR. The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Development. 2018 May 17;145(10). pii: dev159210. doi: 10.1242/dev.159210. |
Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish
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Citation:
Sci Rep. 2018;8:8495 doi:10.1038/s41598-018-26612-0 Epub:
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Activation of hepatic stellate cells (HSC) plays a crucial role in the liver disease progression from liver fibrosis/cirrhosis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Q, Yan C, Gong Z. Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish. Sci Rep. 2018;8:8495 doi:10.1038/s41598-018-26612-0. |
A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease
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Citation:
Sci Rep. 2018 May 24;8(1):8085. doi:10.1038/s41598-018-26460-y Epub:
Not Epub Abstract:
We aimed to analyze the associations of single nucleotide polymorphisms (SNP) in the 5' regulatory region of the human... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun CY, Wu MS, Lee CC, Chen SH, Lo KC, Chen YH. A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease. Sci Rep. 2018 May 24;8(1):8085. doi:10.1038/s41598-018-26460-y. |
Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Shaky Mouse Model of Startle Disease
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Citation:
Front Mol Neurosci. 2018:[Epub]doi:10.3389/fnmol.2018.00167 Epub:
Yes Abstract:
Mutations in GlyR α1 or β subunit genes in humans and rodents lead to severe startle disease characterized by rigidity, massive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schaefer N, Zheng F, van Brederode J, Berger A, Leacock S, Hirata H, Paige CJ, Harvey RJ, Alzheimer C, Villmann C. Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Shaky Mouse Model of Startle Disease. Front Mol Neurosci. 2018:[Epub]doi:10.3389/fnmol.2018.00167. |
Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects
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Citation:
Genome Med. 2018 May 30;10(1):40. doi: 10.1186/s13073-018-0549-y Epub:
Not Epub Abstract:
BACKGROUND: Heterotaxy (Htx) syndrome comprises a class of congenital disorders resulting from malformations in left-right body... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu C, Cao R, Xu Y, Li T, Li F, Chen S, Xu R, Sun K. Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects. Genome Med. 2018 May 30;10(1):40. doi: 10.1186/s13073-018-0549-y. |