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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain

Authors:
Than-Trong E, Ortica-Gatti S, Mella S, Nepal C, Alunni A, Bally-Cuif L
Citation:
Development. 2018 May 15;145(10). pii: dev161034. doi: 10.1242/dev.161034
Epub:
Not Epub
Abstract:
Neural stem cells (NSCs) in the adult vertebrate brain are found in a quiescent state and can preserve long-lasting progenitor...
Link:
http://dev.biologists.org/content/145/10/dev161034
Delivery Method:
intracerebroventricular injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Than-Trong E, Ortica-Gatti S, Mella S, Nepal C, Alunni A, Bally-Cuif L. Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain. Development. 2018 May 15;145(10). pii: dev161034. doi: 10.1242/dev.161034.

Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry

Authors:
Juan T, Géminard C, Coutelis JB, Cerezo D, Polès S, Noselli S, Fürthauer M
Citation:
Nat Commun. 2018 May 16;9(1):1942. doi: 10.1038/s41467-018-04284-8
Epub:
Not Epub
Abstract:
The establishment of left-right (LR) asymmetry is fundamental to animal development, but the identification of a unifying...
Link:
https://www.nature.com/articles/s41467-018-04284-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Juan T, Géminard C, Coutelis JB, Cerezo D, Polès S, Noselli S, Fürthauer M. Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry. Nat Commun. 2018 May 16;9(1):1942. doi: 10.1038/s41467-018-04284-8.

Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity

Authors:
Liu J-X, Xu Q-H, Yu XD, Zhang T, Xie XW, Ouyang G
Citation:
Int J Biol Sci. 2018;14(7):705-16. doi:10.7150/ijbs.18997
Epub:
Not Epub
Abstract:
During early vertebrate embryogenesis, maternal Wnt/β-catenin signaling is thought to locally initiate expression of dorsal-...
Link:
http://www.ijbs.com/v14p0705.htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J-X, Xu Q-H, Yu XD, Zhang T, Xie XW, Ouyang G. Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity. Int J Biol Sci. 2018;14(7):705-16. doi:10.7150/ijbs.18997.

Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice

Authors:
Guo J, Zhang T, Guo Y, Sun T, Li H, Zhang X, Yin H, Cao G, Yin Y, Wang H, Shi L, Guo X, Sha J, Eppig JJ, Su YQ
Citation:
Proc Natl Acad Sci U S A. 2018 May 21. pii: 201800352. doi: 10.1073/pnas.1800352115. [Epub ahead of print]
Epub:
Yes
Abstract:
MTOR (mechanistic target of rapamycin) is a widely recognized integrator of signals and pathways key for cellular metabolism,...
Link:
http://www.pnas.org/content/early/2018/05/15/1800352115
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Guo J, Zhang T, Guo Y, Sun T, Li H, Zhang X, Yin H, Cao G, Yin Y, Wang H, Shi L, Guo X, Sha J, Eppig JJ, Su YQ. Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201800352. doi: 10.1073/pnas.1800352115. [Epub ahead of print].

Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish

Authors:
Guerra A, Germano RF, Stone O, Arnaout R, Guenther S, Ahuja S, Uribe V, Vanhollebeke B, Stainier DY, Reischauer S
Citation:
Elife. 2018 May 15;7. pii: e32833. doi: 10.7554/eLife.32833
Epub:
Not Epub
Abstract:
The ultimate formation of a four-chambered heart allowing the separation of the pulmonary and systemic circuits was key for the...
Link:
https://elifesciences.org/articles/32833
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guerra A, Germano RF, Stone O, Arnaout R, Guenther S, Ahuja S, Uribe V, Vanhollebeke B, Stainier DY, Reischauer S. Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish. Elife. 2018 May 15;7. pii: e32833. doi: 10.7554/eLife.32833.

Retinoic acid induced expression of Hnf1β and Fzd4 is required for pancreas development in Xenopus laevis

Authors:
Gere MB, Pommerenke C, Lingner T, Pieler T
Citation:
Development. 2018 May 16. pii: dev.161372. doi: 10.1242/dev.161372. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid (RA) is required for pancreas specification in Xenopus and other vertebrates. However, the gene network that is...
Link:
http://dev.biologists.org/content/early/2018/05/15/dev.161372
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gere MB, Pommerenke C, Lingner T, Pieler T. Retinoic acid induced expression of Hnf1β and Fzd4 is required for pancreas development in Xenopus laevis. Development. 2018 May 16. pii: dev.161372. doi: 10.1242/dev.161372. [Epub ahead of print].

Extracellular Vesicle-delivered Bone Morphogenetic Proteins: A novel paracrine mechanism during embryonic development

Authors:
Draebing T, Heigwer J, Juergensen L, Katus HA, Hassel D
Citation:
bioRxiv. 2018. doi:10.1101/321356
Epub:
Not Epub
Abstract:
Morphogens including Wnt, Hedgehog and BMP proteins are essential during embryonic development and early induction of organ...
Link:
https://www.biorxiv.org/content/early/2018/05/13/321356
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Draebing T, Heigwer J, Juergensen L, Katus HA, Hassel D. Extracellular Vesicle-delivered Bone Morphogenetic Proteins: A novel paracrine mechanism during embryonic development. bioRxiv. 2018. doi:10.1101/321356.

Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio.

Authors:
Edie S, Zaghloul NA, Leitch CC, Klinedinst DK, Lebron J, Thole JF, McCallion AS, Katsanis N, Reeves RH
Citation:
G3 (Bethesda). 2018 May 14. pii: g3.200144.2018. doi: 10.1534/g3.118.200144. [Epub ahead of print]
Epub:
Yes
Abstract:
Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS), one of the most genetically complex conditions...
Link:
http://www.g3journal.org/content/early/2018/05/14/g3.118.200144.long
Organism or Cell Type:
zebrafish
Citation Extract:
Edie S, Zaghloul NA, Leitch CC, Klinedinst DK, Lebron J, Thole JF, McCallion AS, Katsanis N, Reeves RH. Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio. . G3 (Bethesda). 2018 May 14. pii: g3.200144.2018. doi: 10.1534/g3.118.200144. [Epub ahead of print] .

Role of calcium-sensing receptor in mechanotransducer-channel-mediated Ca2+ influx in hair cells of zebrafish larvae

Authors:
Lin L-Y, Yeh Y-H, Hung G-Y, Lin C-H, Hwang P-P, Horng J-L
Citation:
Front Physiol. 2018;[Epub] doi:10.3389/fphys.2018.00649
Epub:
Not Epub
Abstract:
The calcium-sensing receptor (CaSR) is an extracellular Ca2+ sensor that plays a critical role in maintaining Ca2+ homeostasis...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2018.00649/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Lin L-Y, Yeh Y-H, Hung G-Y, Lin C-H, Hwang P-P, Horng J-L. Role of calcium-sensing receptor in mechanotransducer-channel-mediated Ca2+ influx in hair cells of zebrafish larvae. Front Physiol. 2018;[Epub] doi:10.3389/fphys.2018.00649 .

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132

Authors:
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI
Citation:
Proc Natl Acad Sci U S A. 2018 Aug 23. pii: 201806077. doi: 10.1073/pnas.1806077115. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Epoxyeicosatrienoic acids (EETs) are lipid-derived signaling molecules with cardioprotective and vasodilatory actions. We...
Link:
http://www.pnas.org/content/115/37/9252
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proc Natl Acad Sci U S A. 2018 Aug 23. pii: 201806077. doi: 10.1073/pnas.1806077115. [Epub ahead of print].

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