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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Small GTPase R-Ras participates in neural tube formation in zebrafish embryonic spinal cord
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Citation:
Biochem Biophys Res Commun. 2018 May 14. pii: S0006-291X(18)31131-8. doi: 10.1016/j.bbrc.2018.05.074. [Epub ahead of print] Epub:
Not Epub Abstract:
Ras related (R-Ras), a small GTPase, is involved in the maintenance of apico-basal polarity in neuroepithelial cells of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ohata S, Uga H, Okamoto H, Katada T. Small GTPase R-Ras participates in neural tube formation in zebrafish embryonic spinal cord. Biochem Biophys Res Commun. 2018 May 14. pii: S0006-291X(18)31131-8. doi: 10.1016/j.bbrc.2018.05.074. [Epub ahead of print]. |
The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity
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Citation:
Sci Total Environ. 2018 Aug 15;633:1245-1252. doi: 10.1016/j.scitotenv.2018.03.313. Epub 2018 Mar 30 Epub:
Not Epub Abstract:
Evidence has shown that triphenyltin (TPT) triggers severe malformations in Xenopus tropicalis embryos, partly due to... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Zhu J, Huang X, Jiang H, Hu L, Michal JJ, Jiang Z, Shi H. The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity. Sci Total Environ. 2018 Aug 15;633:1245-1252. doi: 10.1016/j.scitotenv.2018.03.313. Epub 2018 Mar 30. |
Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts
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Citation:
PLoS One. 2018 May 17;13(5):e0197084. doi: 10.1371/journal.pone.0197084. eCollection 2018 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping has made significant progress as a therapeutic platform in recent years, especially in the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary figroblasts differentiated to myotubes Citation Extract: Lee J, Echigoya Y, Duddy W, Saito T, Aoki Y, Takeda S, Yokota T. Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts. PLoS One. 2018 May 17;13(5):e0197084. doi: 10.1371/journal.pone.0197084. eCollection 2018. |
Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis
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Citation:
J Biol Chem. 2017 Oct 27;292(43):17760-17776. doi: 10.1074/jbc.M117.794743. Epub 2017 Sep 14 Epub:
Not Epub Abstract:
Angiogenesis is a highly regulated process for formation of new blood vessels from pre-existing ones. Angiogenesis is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Boopathy GTK, Kulkarni M, Ho SY, Boey A, Chua EWM, Barathi VA, Carney TJ, Wang X, Hong W. Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis. J Biol Chem. 2017 Oct 27;292(43):17760-17776. doi: 10.1074/jbc.M117.794743. Epub 2017 Sep 14. |
Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1
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Citation:
J Biol Chem. 2018 May 2. pii: jbc.RA117.001507. doi: 10.1074/jbc.RA117.001507. [Epub ahead of print] Epub:
Yes Abstract:
The adhesion protein Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is widely expressed in epithelial... Organism or Cell Type:
cell culture: MDA-MB-468(breast cancer) Citation Extract: Dery KJ, Silver C, Yang L, Shively JE. Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1. J Biol Chem. 2018 May 2. pii: jbc.RA117.001507. doi: 10.1074/jbc.RA117.001507. [Epub ahead of print]. |
A SLC4 family bicarbonate transporter is critical for intracellular pH regulation and biomineralization in sea urchin embryos
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Citation:
Elife. 2018 May 1;7. pii: e36600. doi: 10.7554/eLife.36600. [Epub ahead of print] Epub:
Not Epub Abstract:
Efficient pH regulation is a fundamental requisite of all calcifying systems in animals and plants but with the underlying pH... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Hu MY, Yan JJ, Petersen I, Himmerkus N, Bleich M, Stumpp M. A SLC4 family bicarbonate transporter is critical for intracellular pH regulation and biomineralization in sea urchin embryos. Elife. 2018 May 1;7. pii: e36600. doi: 10.7554/eLife.36600. [Epub ahead of print]. |
ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression
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Citation:
Dev Biol. 2018 May 9. pii: S0012-1606(17)30833-3. doi: 10.1016/j.ydbio.2018.05.003. [Epub ahead of print] Epub:
Yes Abstract:
The molecular mechanisms initiating the formation of the lymphatic system, lymphangiogenesis, are still poorly understood. Here... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Davis JA, Koenig AL, Lubert A, Chestnut B, Liu F, Desai SP, Winkler T, Pociute K, Choi K, Sumanas S. ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression. Dev Biol. 2018 May 9. pii: S0012-1606(17)30833-3. doi: 10.1016/j.ydbio.2018.05.003. [Epub ahead of print]. |
Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production
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Citation:
Neurology. 2018 May 11. pii: 10.1212/WNL.0000000000005680. doi: 10.1212/WNL.0000000000005680. [Epub ahead of print] Epub:
Yes Abstract:
OBJECTIVE: To describe the quantification of novel dystrophin production in patients with Duchenne muscular dystrophy (DMD)... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Charleston JS, Schnell FJ, Dworzak J, Donoghue C, Lewis S, Chen L, Young GD, Milici AJ, Voss J, DeAlwis U, Wentworth B, Rodino-Klapac LR, Sahenk Z, Frank D, Mendell JR. Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production. Neurology. 2018 May 11. pii: 10.1212/WNL.0000000000005680. doi: 10.1212/WNL.0000000000005680. [Epub ahead of print]. |
Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain
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Citation:
Dev Cell. 2018 Apr 30. pii: S1534-5807(18)30278-8. doi: 10.1016/j.devcel.2018.04.003. [Epub ahead of print] Epub:
Yes Abstract:
The patterning of tissues to form subdivisions with distinct and homogeneous regional identity is potentially disrupted by cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Addison M, Xu Q, Cayuso J, Wilkinson DG. Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain. Dev Cell. 2018 Apr 30. pii: S1534-5807(18)30278-8. doi: 10.1016/j.devcel.2018.04.003. [Epub ahead of print]. |
A noncanonical function of histidyl-tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development
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Citation:
FEBS Open Bio. 2018 Apr 17;8(5):722-731. doi: 10.1002/2211-5463.12420. eCollection 2018 May Epub:
Not Epub Abstract:
Histidyl-tRNA synthetase (Hars) catalyzes the ligation of histidine residues to cognate tRNA. Here, we demonstrate a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ni R, Luo L. A noncanonical function of histidyl-tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development. FEBS Open Bio. 2018 Apr 17;8(5):722-731. doi: 10.1002/2211-5463.12420. eCollection 2018 May. |