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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Multiple functions for the catenin family member plakoglobin in cadherin-dependent adhesion, fibronectin matrix assembly and Xenopus gastrulation movements

Authors:
Hirsh GD, Dzamba BJ, Sonavane PR, Shook DR, Allen CM, DeSimone DW
Citation:
bioRxiv. 2018. doi:10.1101/318774
Epub:
Not Epub
Abstract:
Shaping an embryo requires tissue-scale cell rearrangements known as morphogenetic events. These force-dependent processes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hirsh GD, Dzamba BJ, Sonavane PR, Shook DR, Allen CM, DeSimone DW. Multiple functions for the catenin family member plakoglobin in cadherin-dependent adhesion, fibronectin matrix assembly and Xenopus gastrulation movements. bioRxiv. 2018. doi:10.1101/318774.

Integrin and ligand-independent PDGFr signaling synergistically contribute to directional migration of Xenopus mesendoderm

Authors:
Richardson CM, Dzamba BJ, Sonavane PR, DeSimone DW
Citation:
bioRxiv. 2018. doi:10.1101/318824
Epub:
Not Epub
Abstract:
Both PDGF signaling and adhesion to fibronectin (FN) matrix have been implicated in the directional collective migration of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Richardson CM, Dzamba BJ, Sonavane PR, DeSimone DW. Integrin and ligand-independent PDGFr signaling synergistically contribute to directional migration of Xenopus mesendoderm. bioRxiv. 2018. doi:10.1101/318824 .

Frequency and synchrony of actomyosin oscillation during PCP-dependent convergent extension

Authors:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB
Citation:
bioRxiv. 2018. doi:10.1101/316745
Epub:
Not Epub
Abstract:
Oscillatory actomyosin flows play a key role in single cell migration and in collective cell movements that shape invertebrates...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB. Frequency and synchrony of actomyosin oscillation during PCP-dependent convergent extension. bioRxiv. 2018. doi:10.1101/316745.

The N-terminal domain of gastrulation brain homeobox 2 (Gbx2) is required for iridophore specification in zebrafish

Authors:
Hozumi S, Shirai M, Wang J, Aoki S, Kikuchi Y
Citation:
Biochem Biophys Res Commun. 2018 May 19. pii: S0006-291X(18)31197-5. doi: 10.1016/j.bbrc.2018.05.128. [Epub ahead of print]
Epub:
Yes
Abstract:
Although body color pattern formation by pigment cells plays critical roles in animals, pigment cell specification has not yet...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hozumi S, Shirai M, Wang J, Aoki S, Kikuchi Y. The N-terminal domain of gastrulation brain homeobox 2 (Gbx2) is required for iridophore specification in zebrafish. Biochem Biophys Res Commun. 2018 May 19. pii: S0006-291X(18)31197-5. doi: 10.1016/j.bbrc.2018.05.128. [Epub ahead of print].

β-Catenin-dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria

Authors:
Pukhlyakova E, Aman AJ, Elsayad K, Technau U
Citation:
Proc Natl Acad Sci U S A. 2018 May 21. pii: 201713682. doi: 10.1073/pnas.1713682115. [Epub ahead of print]
Epub:
Yes
Abstract:
Although the genetic regulation of cellular differentiation processes is well established, recent studies have revealed the...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Pukhlyakova E, Aman AJ, Elsayad K, Technau U. β-Catenin-dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201713682. doi: 10.1073/pnas.1713682115. [Epub ahead of print].

Heart enhancers with deeply conserved regulatory activity are established early in development

Authors:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD
Citation:
Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z
Epub:
Not Epub
Abstract:
During the phylotypic period, embryos from different genera show similar gene expression patterns, implying common regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD. Heart enhancers with deeply conserved regulatory activity are established early in development. Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z.

Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish

Authors:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S
Citation:
Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May
Epub:
Not Epub
Abstract:
Objective: DEPDC5 was identified as a major genetic cause of focal epilepsy with deleterious mutations found in a wide range of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S. Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish. Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May.

Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish

Authors:
Berrun A, Harris E, Stachura DL
Citation:
PLoS One. 2018 May 14;13(5):e0196872. doi: 10.1371/journal.pone.0196872. eCollection 2018
Epub:
Not Epub
Abstract:
Hematopoiesis is an essential and highly regulated biological process that begins with hematopoietic stem cells (HSCs). In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berrun A, Harris E, Stachura DL. Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish. PLoS One. 2018 May 14;13(5):e0196872. doi: 10.1371/journal.pone.0196872. eCollection 2018.

Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish

Authors:
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran MC, Sittaramane V, Chandrasekhar A
Citation:
Mech Dev. 2018 May 16. pii: S0925-4773(18)30082-0. doi: 10.1016/j.mod.2018.05.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Contactin2 (Cntn2)/Transient Axonal Glycoprotein 1 (Tag1), a neural cell adhesion molecule, has established roles in neuronal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran MC, Sittaramane V, Chandrasekhar A. Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish. Mech Dev. 2018 May 16. pii: S0925-4773(18)30082-0. doi: 10.1016/j.mod.2018.05.005. [Epub ahead of print].

GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer

Authors:
Checa-Rojas A, Delgadillo-Silva LF, Velasco-Herrera MDC, Andrade-Domínguez A, Gil J, Santillán O, Lozano L, Toledo-Leyva A, Ramírez-Torres A, Talamas-Rohana P, Encarnación-Guevara S
Citation:
Oncotarget. 2018 Apr 24;9(31):21696-21714. doi: 10.18632/oncotarget.24796. eCollection 2018 Apr 24
Epub:
Not Epub
Abstract:
The molecular processes and proteomic markers leading to tumor progression (TP) in cervical cancer (CC) are either unknown or...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: HeLa, HaCaT, SiHA, CC; murine xenograft: SiHa, CaSki, HeLa, CaLo, MDA, CoLo
Citation Extract:
Checa-Rojas A, Delgadillo-Silva LF, Velasco-Herrera MDC, Andrade-Domínguez A, Gil J, Santillán O, Lozano L, Toledo-Leyva A, Ramírez-Torres A, Talamas-Rohana P, Encarnación-Guevara S. GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer. Oncotarget. 2018 Apr 24;9(31):21696-21714. doi: 10.18632/oncotarget.24796. eCollection 2018 Apr 24.

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