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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy
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Citation:
Cell Mol Gastroenterol Hepatol. 2018 Mar 6;6(1):47-63. doi: 10.1016/j.jcmgh.2018.02.008. eCollection 2018 Epub:
Not Epub Abstract:
Background & Aims: Hepatic encephalopathy is a serious neurologic complication of acute and chronic liver diseases. We... Delivery Method:
Vivo-Morpholino & Endo-Porter, Alzet pump Organism or Cell Type:
C57Bl/6 mice Citation Extract: McMillin M, Grant S, Frampton G, Petrescu AD, Kain J, Williams E, Haines R, Canady L, DeMorrow S. FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy. Cell Mol Gastroenterol Hepatol. 2018 Mar 6;6(1):47-63. doi: 10.1016/j.jcmgh.2018.02.008. eCollection 2018. |
Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression
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Citation:
PLoS One. 2018 Jun 21;13(6):e0199233. doi: 10.1371/journal.pone.0199233. eCollection 2018 Epub:
Not Epub Abstract:
Zebrafish primary motor neurons differ from each other with respect to morphology, muscle targets and electrophysiological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moreno RL, Williams K, Jones KL, Ribera AB. Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression. PLoS One. 2018 Jun 21;13(6):e0199233. doi: 10.1371/journal.pone.0199233. eCollection 2018. |
Synthesis, Characterization, and Function of an RNA-Based Transfection Reagent
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Citation:
Curr Protoc Nucleic Acid Chem. 2018 Mar;72(1):4.81.1-4.81.29. doi: 10.1002/cpnc.51 Epub:
Not Epub Abstract:
A synthetic 8-mer, amphipathic, trans-acting poly-2'-O-methyluridylic thiophosphate triester RNA element (2'-OMeUtaPS... Delivery Method:
2'-O-Me-PS-RNA carrier Organism or Cell Type:
cell culture: HeLa pLuc 705, mice mdx Citation Extract: Jain HV, Boehler JF, Nagaraju K, Beaucage SL. Synthesis, Characterization, and Function of an RNA-Based Transfection Reagent. Curr Protoc Nucleic Acid Chem. 2018 Mar;72(1):4.81.1-4.81.29. doi: 10.1002/cpnc.51. |
Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach
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Citation:
BMC Dev Biol. 2018 Jun 19;18(1):14. doi: 10.1186/s12861-018-0173-5 Epub:
Not Epub Abstract:
BACKGROUND: Dmrt2a is a zinc finger like transcription factor with several roles during zebrafish early development: left-right... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pinto RA, Almeida-Santos J, Lourenço R, Saúde L. Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach. BMC Dev Biol. 2018 Jun 19;18(1):14. doi: 10.1186/s12861-018-0173-5. |
Assessing the role of the acid-sensing ion channel ASIC4b in sodium uptake by larval zebrafish
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Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2018 Jun 15;226:1-10. doi: 10.1016/j.cbpa.2018.06.012. [Epub ahead of print] Epub:
Yes Abstract:
Na+ uptake in larval zebrafish (Danio rerio) is coordinated by three mechanisms: Na+/H+-exchanger 3b (NHE3b) expressed in H+-... Organism or Cell Type:
zebrafish Citation Extract: Zimmer AM, Dymowska AK, Kumai Y, Goss GG, Perry SF, Kwong RWM. Assessing the role of the acid-sensing ion channel ASIC4b in sodium uptake by larval zebrafish. Comp Biochem Physiol A Mol Integr Physiol. 2018 Jun 15;226:1-10. doi: 10.1016/j.cbpa.2018.06.012. [Epub ahead of print]. |
Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy
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Citation:
PLoS One. 2018 Jun 18;13(6):e0198897. doi: 10.1371/journal.pone.0198897. eCollection 2018 Epub:
Not Epub Abstract:
Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA... Delivery Method:
peptide-linked Organism or Cell Type:
mice mdx Citation Extract: Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA, Straub VW. Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy. PLoS One. 2018 Jun 18;13(6):e0198897. doi: 10.1371/journal.pone.0198897. eCollection 2018. |
Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly
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Citation:
Hum Mol Genet. 2018 Jun 14. doi: 10.1093/hmg/ddy218. [Epub ahead of print] Epub:
Yes Abstract:
Central conducting lymphatic anomaly (CCLA) is one of the complex lymphatic anomalies characterized by dilated lymphatic... Organism or Cell Type:
zebrafish Citation Extract: Li D, Wenger TL, Seiler C, March ME, Gutierrez-Uzquiza A, Kao C, Bhoj E, Tian L, Rosenbach M, Liu Y, Robinson N, Behr M, Chiavacci R, Hou C, Wang T, Bakay M, Pellegrino da Silva R, Perkins JA, Sleiman P, Levine MA, Hicks PJ, Itkin M, Dori Y, Hakonarson H. Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly. Hum Mol Genet. 2018 Jun 14. doi: 10.1093/hmg/ddy218. [Epub ahead of print]. |
LHX2 Mediates the FGF-to-SHH Regulatory Loop during Limb Development
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Citation:
J Dev Biol. 2018 Jun 15;6(2). pii: E13. doi: 10.3390/jdb6020013 Epub:
Not Epub Abstract:
During limb development, fibroblast growth factors (Fgfs) govern proximal⁻distal outgrowth and patterning. FGFs also... Delivery Method:
injection and electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Watson BA, Feenstra JM, Van Arsdale JM, Rai-Bhatti KS, Kim DJH, Coggins AS, Mattison GL, Yoo S, Steinman ED, Pira CU, Gongol BR, Oberg KC. LHX2 Mediates the FGF-to-SHH Regulatory Loop during Limb Development. J Dev Biol. 2018 Jun 15;6(2). pii: E13. doi: 10.3390/jdb6020013. |
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
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Citation:
Nat Comm. 2018;2292(9):[Epub] doi:10.1038/s41467-018-04602-0 Epub:
Not Epub Abstract:
Oxidized phospholipids (oxPAPC) induce endothelial dysfunction and atherosclerosis. Here we show that oxPAPC induce a gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, Thomas D, Giral H, Schreiber Y, Geisslinger G, Fork C, Yang X, Sigala F, Romanoski CE, Kroll J, Jo H, Landmesser U, Lusis AJ, Namgaladze D, Fleming I, Leisegang MS, Zhu J, Brandes RP. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nat Comm. 2018;2292(9):[Epub] doi:10.1038/s41467-018-04602-0. |
ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells
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Citation:
iScience. 2018 Apr 27;2:88-100. doi: 10.1016/j.isci.2018.03.010 Epub:
Not Epub Abstract:
Cardiac development requires coordinated biphasic regulation of the WNT/β-catenin signaling pathway. By intersecting gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hofsteen P, Robitaille AM, Strash N, Palpant N, Moon RT, Pabon L, Murry CE. ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells. iScience. 2018 Apr 27;2:88-100. doi: 10.1016/j.isci.2018.03.010. |