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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio

Authors:
Morris JF, Chomyk A, Song P, Parker N, Deckard S, Trapp BD, Pimplikar SW, Dutta R
Citation:
Invert Neurosci. 2015;15:4 doi:10.1007/s10158-015-0180-1
Epub:
Not Epub
Abstract:
Oligodendrocytes produce multi-lamellar myelin membranes that surround axons in the central nervous system (CNS). Preservation...
Organism or Cell Type:
zebrafish
Citation Extract:
Morris JF, Chomyk A, Song P, Parker N, Deckard S, Trapp BD, Pimplikar SW, Dutta R. Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio. Invert Neurosci. 2015;15:4 doi:10.1007/s10158-015-0180-1.

Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32

Authors:
Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM
Citation:
J Biol Chem. 2015 May 12. pii: jbc.M115.650747. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Tryptophan was substituted for residues in all four transmembrane domains of connexin32. Function was assayed using dual cell...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM. Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32. J Biol Chem. 2015 May 12. pii: jbc.M115.650747. [Epub ahead of print].

Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of R-Smads to Ensure TGFβ-mediated Germ Layer Induction in Xenopus Embryos

Authors:
Sun G, Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X, Chen YG, Zhang MQ, Tao Q, Wu W
Citation:
J Biol Chem. 2015 May 26. pii: jbc.M115.655605. [Epub ahead of print]
Epub:
Yes
Abstract:
Germ layer induction is one of the earliest events shortly after fertilization that initiates body formation of vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sun G, Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X, Chen YG, Zhang MQ, Tao Q, Wu W. Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of R-Smads to Ensure TGFβ-mediated Germ Layer Induction in Xenopus Embryos. J Biol Chem. 2015 May 26. pii: jbc.M115.655605. [Epub ahead of print].

Highly sensitive detection of sequence-specific DNA with morpholino-functionalized magnetic microspheres

Authors:
Hu W, Ning Y, Li L, Kong J, Zhang X
Citation:
Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C5AY00628G
Epub:
Yes
Abstract:
In this work, a highly effective biosensor supported on morpholino-functionalized magnetic microspheres was investigated for...
Citation Extract:
Hu W, Ning Y, Li L, Kong J, Zhang X. Highly sensitive detection of sequence-specific DNA with morpholino-functionalized magnetic microspheres. Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C5AY00628G.

Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment

Authors:
Pagán AJ, Chao-Tsung YangC-T, Cameron J, Swaim LE, Ellett F, Lieschke GJ, Ramakrishnan L
Citation:
Cell Host & Microbe. 2015;18(1):15-26. doi:10.1016/j.chom.2015.06.008
Epub:
Not Epub
Abstract:
The mycobacterial ESX-1 virulence locus accelerates macrophage recruitment to the forming tuberculous granuloma. Newly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pagán AJ, Chao-Tsung YangC-T, Cameron J, Swaim LE, Ellett F, Lieschke GJ, Ramakrishnan L. Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment. Cell Host & Microbe. 2015;18(1):15-26. doi:10.1016/j.chom.2015.06.008.

Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential

Authors:
Cator LJ, Pietri JE, Murdock CC, Ohm JR, Lewis EE, Read AF, Luckhart S, Thomas MB
Citation:
Sci Rep. 2015;5:11947 doi:10.1038/srep11947
Epub:
Not Epub
Abstract:
Malaria parasites alter mosquito feeding behaviour in a way that enhances parasite transmission. This is widely considered a...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Anopheles stephensi (mosquito)
Citation Extract:
Cator LJ, Pietri JE, Murdock CC, Ohm JR, Lewis EE, Read AF, Luckhart S, Thomas MB. Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential. Sci Rep. 2015;5:11947 doi:10.1038/srep11947.

Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome

Authors:
Rapchak CE, Patel N, Hudson J, Crawford M
Citation:
Biochem Cell Biol. 2015 May 25:1-9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The polo-like kinases are a family of conserved serine/threonine kinases that play multiple roles in regulation of the cell...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rapchak CE, Patel N, Hudson J, Crawford M. Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome. Biochem Cell Biol. 2015 May 25:1-9. [Epub ahead of print].

A conserved role of αA-crystallin in the development of the zebrafish embryonic lens

Authors:
Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS
Citation:
Exp Eye Res. 2015 Jul 3. pii: S0014-4835(15)00220-1. doi: 10.1016/j.exer.2015.07.001. [Epub ahead of print]
Epub:
Yes
Abstract:
αA- and αB-crystallins are small heat shock proteins that bind thermodynamically destabilized proteins thereby inhibiting their...
Organism or Cell Type:
zebrafish
Citation Extract:
Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS. A conserved role of αA-crystallin in the development of the zebrafish embryonic lens. Exp Eye Res. 2015 Jul 3. pii: S0014-4835(15)00220-1. doi: 10.1016/j.exer.2015.07.001. [Epub ahead of print].

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

Authors:
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L
Citation:
PNAS. 2015;112(27):E3495-E3504. doi:10.1073/pnas.1507105112
Epub:
Not Epub
Abstract:
Damage repair mechanisms at transcriptionally active sites during the G0/G1 phase are largely unknown. To elucidate these...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination. PNAS. 2015;112(27):E3495-E3504. doi:10.1073/pnas.1507105112.

In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress

Authors:
Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE
Citation:
PLoS Genet. 2015;11(7):e1005349. doi:10.1371/journal.pgen.1005349
Epub:
Not Epub
Abstract:
African Americans have a disproportionate risk for developing nephropathy. This disparity has been attributed to coding...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE. In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. PLoS Genet. 2015;11(7):e1005349. doi:10.1371/journal.pgen.1005349.

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