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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints

Authors:
Genikhovich G, Fried P, Prünster MM, Schinko JB, Gilles AF, Fredman D, Meier K, Iber D, Technau U
Citation:
Cell Reports. 2015. doi:10.1016/j.celrep.2015.02.035
Epub:
Not Epub
Abstract:
BMP signaling plays a crucial role in the establishment of the dorso-ventral body axis in bilaterally symmetric animals....
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Genikhovich G, Fried P, Prünster MM, Schinko JB, Gilles AF, Fredman D, Meier K, Iber D, Technau U. Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints. Cell Reports. 2015. doi:10.1016/j.celrep.2015.02.035.

Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice

Authors:
Betts CA, Saleh AF, Carr CA, Hammond SM, Coenen-Stass AM, Godfrey C, McClorey G, Varela MA, Roberts TC, Clarke K, Gait MJ, Wood MJ
Citation:
Sci Rep. 2015 Mar 11;5:8986. doi: 10.1038/srep08986
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disorder caused by mutations in the Dmd gene. In addition to...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Betts CA, Saleh AF, Carr CA, Hammond SM, Coenen-Stass AM, Godfrey C, McClorey G, Varela MA, Roberts TC, Clarke K, Gait MJ, Wood MJ. Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice. Sci Rep. 2015 Mar 11;5:8986. doi: 10.1038/srep08986.

Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos

Authors:
Brannon MK, Davis JM, Mathias JR, Hall CJ, Emerson JC, Crosier PS, Huttenlocher A, Ramakrishnan L, Moskowitz SM
Citation:
Cell Microbiol. 2009 May;11(5):755-68. doi: 10.1111/j.1462-5822.2009.01288.x. Epub 2009 Jan 15
Epub:
Not Epub
Abstract:
Pseudomonas aeruginosa is an opportunistic human pathogen that can cause serious infection in those with deficient or impaired...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brannon MK, Davis JM, Mathias JR, Hall CJ, Emerson JC, Crosier PS, Huttenlocher A, Ramakrishnan L, Moskowitz SM. Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos. Cell Microbiol. 2009 May;11(5):755-68. doi: 10.1111/j.1462-5822.2009.01288.x. Epub 2009 Jan 15.

Transcriptional and metabolic effects of glucocorticoid receptor α and β signaling in zebrafish

Authors:
Chatzopoulou A, Roy U, Meijer AH, Alia A, Spaink HP, Schaaf MJ
Citation:
Endocrinology. 2015 Mar 10:en20141941. [Epub ahead of print]
Epub:
Yes
Abstract:
In humans and zebrafish, two glucocorticoid receptor splice variants exist: the canonical GR α-isoform (GRα), and the GR β-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chatzopoulou A, Roy U, Meijer AH, Alia A, Spaink HP, Schaaf MJ. Transcriptional and metabolic effects of glucocorticoid receptor α and β signaling in zebrafish. Endocrinology. 2015 Mar 10:en20141941. [Epub ahead of print].

Tbx6, Mesp-b and Ripply1 regulate the onset of skeletal myogenesis in zebrafish

Authors:
Windner SE, Doris RA, Ferguson CM, Nelson AC, Valentin G, Tan H, Oates AC, Wardle FC, Devoto SH
Citation:
Development. 2015 Feb 27. pii: dev.113431. [Epub ahead of print]
Epub:
Yes
Abstract:
During embryonic development, the paraxial mesoderm becomes segmented into somites, within which proliferative muscle...
Organism or Cell Type:
zebrafish
Citation Extract:
Windner SE, Doris RA, Ferguson CM, Nelson AC, Valentin G, Tan H, Oates AC, Wardle FC, Devoto SH. Tbx6, Mesp-b and Ripply1 regulate the onset of skeletal myogenesis in zebrafish. Development. 2015 Feb 27. pii: dev.113431. [Epub ahead of print].

The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in Xenopus

Authors:
Griffin JN, Sondalle SB, del Viso F, Baserga SJ, Khokha MK
Citation:
PLoS Genet. 2015;11(3):e1005018. doi:10.1371/journal.pgen.1005018
Epub:
Not Epub
Abstract:
The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Griffin JN, Sondalle SB, del Viso F, Baserga SJ, Khokha MK. The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in Xenopus. PLoS Genet. 2015;11(3):e1005018. doi:10.1371/journal.pgen.1005018.

Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin

Authors:
Stooke-Vaughan GA, Obholzer ND, Baxendale S, Megason SG, Whitfield TT
Citation:
Development. 2015;142:1137-45. doi:10.1242/dev.116632
Epub:
Not Epub
Abstract:
Otoliths are biomineralised structures important for balance and hearing in fish. Their counterparts in the mammalian inner ear...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stooke-Vaughan GA, Obholzer ND, Baxendale S, Megason SG, Whitfield TT. Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin. Development. 2015;142:1137-45. doi:10.1242/dev.116632.

Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9

Authors:
Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA
Citation:
Development. 2015 Feb 27. pii: dev.117424. [Epub ahead of print]
Epub:
Yes
Abstract:
Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disorder...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development. 2015 Feb 27. pii: dev.117424. [Epub ahead of print].

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation

Authors:
Acosta H, Iliev D, Grahn THM, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM
Citation:
Development. 2015;142:1146-1158. doi:10.1242/dev.113886
Epub:
Yes
Abstract:
Germ layer formation and primary axis development rely on Fibroblast growth factors (FGFs). In Xenopus, the secreted serine...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Acosta H, Iliev D, Grahn THM, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM. The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation. Development. 2015;142:1146-1158. doi:10.1242/dev.113886.

Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy

Authors:
Gramlich M, Pane LS, Zhou Q, Chen Z, Murgia M, Schötterl S, Goedel A, Metzger K, Brade T, Parrotta E, Schaller M, Gerull B, Thierfelder L, Aartsma-Rus A, Labeit S, Atherton JJ, McGaughran J, Harvey RP, Sinnecker D, Mann M, Laugwitz K-L, Gawaz MP, Moretti A
Citation:
EMBO Mol Med. 2015;[Epub ahead of print] doi:10.15252/emmm.201505047
Epub:
Not Epub
Abstract:
Frameshift mutations in the TTN gene encoding titin are a major cause for inherited forms of dilated cardiomyopathy (DCM), a...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Gramlich M, Pane LS, Zhou Q, Chen Z, Murgia M, Schötterl S, Goedel A, Metzger K, Brade T, Parrotta E, Schaller M, Gerull B, Thierfelder L, Aartsma-Rus A, Labeit S, Atherton JJ, McGaughran J, Harvey RP, Sinnecker D, Mann M, Laugwitz K-L, Gawaz MP, Moretti A. Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy. EMBO Mol Med. 2015;[Epub ahead of print] doi:10.15252/emmm.201505047.

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