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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo

Authors:
Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni C-W, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D
Citation:
Development. 2015;142:1050-1061. doi:10.1242/dev.119180
Epub:
Not Epub
Abstract:
The adult blood system is established by hematopoietic stem cells (HSCs), which arise during development from an endothelial-to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni C-W, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D. Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development. 2015;142:1050-1061. doi:10.1242/dev.119180 .

MASH1/Ascl1a Leads to GAP43 Expression and Axon Regeneration in the Adult CNS

Authors:
Williams RR, Venkatesh I, Pearse DD, Udvadia AJ, Bunge MB
Citation:
PLoS ONE. 2015;10(3):e0118918. doi:10.1371/journal.pone.0118918
Epub:
Not Epub
Abstract:
Unlike CNS neurons in adult mammals, neurons in fish and embryonic mammals can regenerate their axons after injury. These...
Delivery Method:
gelfoam at lesion
Organism or Cell Type:
zebrafish
Citation Extract:
Williams RR, Venkatesh I, Pearse DD, Udvadia AJ, Bunge MB. MASH1/Ascl1a Leads to GAP43 Expression and Axon Regeneration in the Adult CNS. PLoS ONE. 2015;10(3):e0118918. doi:10.1371/journal.pone.0118918.

BDNF-TrkB Axis Regulates Migration of the Lateral Line Primordium and Modulates the Maintenance of Mechanoreceptor Progenitors

Authors:
Gasanov EV, Rafieva LM, Korzh VP
Citation:
PLoS ONE. 2015;10(3):e0119711. doi:10.1371/journal.pone.0119711
Epub:
Not Epub
Abstract:
.BDNF and its specialized receptor TrkB are expressed in the developing lateral line system of zebrafish, but their role in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gasanov EV, Rafieva LM, Korzh VP. BDNF-TrkB Axis Regulates Migration of the Lateral Line Primordium and Modulates the Maintenance of Mechanoreceptor Progenitors. PLoS ONE. 2015;10(3):e0119711. doi:10.1371/journal.pone.0119711.

Claudin-10 is required for relay of left-right patterning cues from Hensen's node to the lateral plate mesoderm

Authors:
Collins MM, Amanda IB, Simard A, Gregory M, Cyr DG, Ryan AK
Citation:
Dev Biol. 2015 Mar 2. pii: S0012-1606(15)00089-5. doi: 10.1016/j.ydbio.2015.02.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Species-specific symmetry-breaking events at the left-right organizer (LRO) drive an evolutionarily-conserved cascade of gene...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Collins MM, Amanda IB, Simard A, Gregory M, Cyr DG, Ryan AK. Claudin-10 is required for relay of left-right patterning cues from Hensen's node to the lateral plate mesoderm. Dev Biol. 2015 Mar 2. pii: S0012-1606(15)00089-5. doi: 10.1016/j.ydbio.2015.02.019. [Epub ahead of print].

Cell Adhesion Mediated by VCAM–ITGa9 Interactions Enables Lymphatic Development

Authors:
Yang Y, Enis D, Zheng H, Chia S, Yang Y, Chen M, Dhillon V, Papayannapoulou T, Kahn ML
Citation:
Arterioscler Thromb Vasc Biol. 2015;[Epub ahead of print] doi:10.1161/ATVBAHA.114.304997
Epub:
Yes
Abstract:
Objective—Adhesive ligand–receptor interactions play key roles in blood vessel angiogenesis but remain poorly characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Y, Enis D, Zheng H, Chia S, Yang Y, Chen M, Dhillon V, Papayannapoulou T, Kahn ML. Cell Adhesion Mediated by VCAM–ITGa9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol. 2015;[Epub ahead of print] doi:10.1161/ATVBAHA.114.304997.

Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo

Authors:
Eagleson G, Pfister K, Knowlton AL, Skoglund P, Keller R, Stukenberg PT
Citation:
Mol Biol Cell. 2015 Mar 1;26(5):924-37. doi: 10.1091/mbc.E13-12-0721. Epub 2015 Jan 7
Epub:
Not Epub
Abstract:
Kif2a is a member of the kinesin-13 microtubule depolymerases, which tightly regulate microtubule dynamics for many cellular...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Eagleson G, Pfister K, Knowlton AL, Skoglund P, Keller R, Stukenberg PT. Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo. Mol Biol Cell. 2015 Mar 1;26(5):924-37. doi: 10.1091/mbc.E13-12-0721. Epub 2015 Jan 7.

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

Authors:
Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R
Citation:
Nucleic Acids Res. 2015 Mar 3. pii: gkv157. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in FUS cause amyotrophic lateral sclerosis (ALS), but the molecular pathways leading to neurodegeneration remain...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R. U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish. Nucleic Acids Res. 2015 Mar 3. pii: gkv157. [Epub ahead of print].

Epigenetic control of intestinal barrier function and inflammation in zebrafish

Authors:
Marjoram L, Alvers A, Deerhake ME, Bagwell J, Mankiewicz J, Cocchiaro JL, Beerman RW, Willer J, Sumigray KD, Katsanis N, Tobin DM, Rawls JF, Goll MG, Bagnat M
Citation:
Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2770-5. doi: 10.1073/pnas.1424089112. Epub 2015 Feb 17
Epub:
Not Epub
Abstract:
The intestinal epithelium forms a barrier protecting the organism from microbes and other proinflammatory stimuli. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marjoram L, Alvers A, Deerhake ME, Bagwell J, Mankiewicz J, Cocchiaro JL, Beerman RW, Willer J, Sumigray KD, Katsanis N, Tobin DM, Rawls JF, Goll MG, Bagnat M. Epigenetic control of intestinal barrier function and inflammation in zebrafish. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2770-5. doi: 10.1073/pnas.1424089112. Epub 2015 Feb 17.

IFT46 plays an essential role in cilia development

Authors:
Lee MS, Hwang KS, Oh HW, Ji-Ae K, Kim HT, Cho HS, Lee JJ, Yeong Ko J, Choi JH, Jeong YM, You KH, Kim J, Park DS, Nam KH, Aizawa S, Kiyonari H, Shioi G, Park JH, Zhou W, Kim NS, Kim CH
Citation:
Dev Biol. 2015 Feb 24. pii: S0012-1606(15)00067-6. doi: 10.1016/j.ydbio.2015.02.009. [Epub ahead of print]
Epub:
Yes
Abstract:
Cilia are microtubule-based structures that project into the extracellular space. Ciliary defects are associated with several...
Organism or Cell Type:
zebrafish
Citation Extract:
Lee MS, Hwang KS, Oh HW, Ji-Ae K, Kim HT, Cho HS, Lee JJ, Yeong Ko J, Choi JH, Jeong YM, You KH, Kim J, Park DS, Nam KH, Aizawa S, Kiyonari H, Shioi G, Park JH, Zhou W, Kim NS, Kim CH. IFT46 plays an essential role in cilia development. Dev Biol. 2015 Feb 24. pii: S0012-1606(15)00067-6. doi: 10.1016/j.ydbio.2015.02.009. [Epub ahead of print].

Biochemical Characterization of Three BLT Receptors in Zebrafish

Authors:
Okuno T, Ishitani T, Yokomizo T
Citation:
PLoS One. 2015 Mar 4;10(3):e0117888. doi: 10.1371/journal.pone.0117888. eCollection 2015
Epub:
Not Epub
Abstract:
The leukotriene B4 (LTB4) receptor 1 (BLT1) is a high affinity receptor for LTB4, a chemotactic and inflammatory eicosanoid....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okuno T, Ishitani T, Yokomizo T. Biochemical Characterization of Three BLT Receptors in Zebrafish. PLoS One. 2015 Mar 4;10(3):e0117888. doi: 10.1371/journal.pone.0117888. eCollection 2015.

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