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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins

Authors:
Hirose K, Shiomi T, Hozumi S, Kikuchi Y
Citation:
BMC Dev Biol. 2014 Dec 6;14(1):42. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background: The mechanistic target of rapamycin complex1 (mTORC1) signaling pathway has been implicated in functions of...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hirose K, Shiomi T, Hozumi S, Kikuchi Y. Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins. BMC Dev Biol. 2014 Dec 6;14(1):42. [Epub ahead of print].

Analysis of skeletal muscle defects in larval zebrafish by birefringence and touch-evoke escape response assays

Authors:
Smith LL, Beggs AH, Gupta VA
Citation:
J Vis Exp. 2013 Dec 13;(82):e50925. doi: 10.3791/50925
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) have become a particularly effective tool for modeling human diseases affecting skeletal muscle,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith LL, Beggs AH, Gupta VA. Analysis of skeletal muscle defects in larval zebrafish by birefringence and touch-evoke escape response assays. J Vis Exp. 2013 Dec 13;(82):e50925. doi: 10.3791/50925.

Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL

Authors:
Burgoyne T, O'Connor MN, Seabra MC, Cutler DF, Futter CE
Citation:
J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.164400
Epub:
Yes
Abstract:
Analysis of melanosome biogenesis in the retinal pigment epithelium (RPE) is challenging because it occurs predominantly in a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burgoyne T, O'Connor MN, Seabra MC, Cutler DF, Futter CE. Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL. J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.164400.

Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac neural crest versus heart mesoderm

Authors:
Nie S, Bronner ME
Citation:
Cardiovasc Res. 2015;[Epub ahead of print] doi:/10.1093/cvr/cvv043
Epub:
Yes
Abstract:
Aims: Ets1 is an important transcription factor that is expressed in both the cardiac neural crest and heart mesoderm of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nie S, Bronner ME. Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac neural crest versus heart mesoderm. Cardiovasc Res. 2015;[Epub ahead of print] doi:/10.1093/cvr/cvv043.

An anti-inflammatory NOD-like receptor is required for microglia development

Authors:
Shiau CE, Monk KR, Joo W, Talbot WS
Citation:
Cell Rep. 2013 Dec 12;5(5):1342-52. doi: 10.1016/j.celrep.2013.11.004. Epub 2013 Dec 5
Epub:
Not Epub
Abstract:
Microglia are phagocytic cells that form the basis of the brain's immune system. They derive from primitive macrophages...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shiau CE, Monk KR, Joo W, Talbot WS. An anti-inflammatory NOD-like receptor is required for microglia development. Cell Rep. 2013 Dec 12;5(5):1342-52. doi: 10.1016/j.celrep.2013.11.004. Epub 2013 Dec 5.

Loss of Tropomodulin4 in the zebrafish mutant träge causes cytoplasmic rod formation and muscle weakness reminiscent of nemaline myopathy

Authors:
Berger J, Tarakci H, Berger S, Li M, Hall TE, Arner A, Currie PD
Citation:
Dis Model Mech. 2014 Dec;7(12):1407-15. doi: 10.1242/dmm.017376. Epub 2014 Oct 2
Epub:
Not Epub
Abstract:
Nemaline myopathy is an inherited muscle disease that is mainly diagnosed by the presence of nemaline rods in muscle biopsies....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berger J, Tarakci H, Berger S, Li M, Hall TE, Arner A, Currie PD. Loss of Tropomodulin4 in the zebrafish mutant träge causes cytoplasmic rod formation and muscle weakness reminiscent of nemaline myopathy. Dis Model Mech. 2014 Dec;7(12):1407-15. doi: 10.1242/dmm.017376. Epub 2014 Oct 2.

Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells

Authors:
Zhang Z, Rankin SA, Zorn AM
Citation:
Dev Biol. 2013 Jun 1;378(1):1-12. doi: 10.1016/j.ydbio.2013.02.024. Epub 2013 Apr 3
Epub:
Not Epub
Abstract:
Wnt signaling has multiple dynamic roles during development of the gastrointestinal and respiratory systems. Differential Wnt...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhang Z, Rankin SA, Zorn AM. Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol. 2013 Jun 1;378(1):1-12. doi: 10.1016/j.ydbio.2013.02.024. Epub 2013 Apr 3.

RA and FGF signalling are required in the zebrafish otic vesicle to pattern and maintain ventral otic identities

Authors:
Maier EC, Whitfield TT
Citation:
PLoS Genet. 2014 Dec 4;10(12):e1004858. doi: 10.1371/journal.pgen.1004858. eCollection 2014 Dec
Epub:
Not Epub
Abstract:
During development of the zebrafish inner ear, regional patterning in the ventral half of the otic vesicle establishes zones of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maier EC, Whitfield TT. RA and FGF signalling are required in the zebrafish otic vesicle to pattern and maintain ventral otic identities. PLoS Genet. 2014 Dec 4;10(12):e1004858. doi: 10.1371/journal.pgen.1004858. eCollection 2014 Dec.

The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance

Authors:
Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D
Citation:
Blood. 2013 Dec 5;122(24):3918-28. doi: 10.1182/blood-2012-12-475392. Epub 2013 Oct 15
Epub:
Not Epub
Abstract:
Granulocyte colony-stimulating factor (Gcsf) drives the proliferation and differentiation of granulocytes, monocytes, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D. The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 2013 Dec 5;122(24):3918-28. doi: 10.1182/blood-2012-12-475392. Epub 2013 Oct 15.

BMP-mediated specification of the erythroid lineage suppresses endothelial development in blood island precursors

Authors:
Myers CT, Krieg PA
Citation:
Blood. 2013 Dec 5;122(24):3929-39. doi: 10.1182/blood-2013-03-490045. Epub 2013 Oct 7
Epub:
Not Epub
Abstract:
The developmental relationship between the blood and endothelial cell (EC) lineages remains unclear. In the extra-embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Myers CT, Krieg PA. BMP-mediated specification of the erythroid lineage suppresses endothelial development in blood island precursors. Blood. 2013 Dec 5;122(24):3929-39. doi: 10.1182/blood-2013-03-490045. Epub 2013 Oct 7.

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