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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level

Authors:
Pereverzev AP, Gurskaya NG, Ermakova GV, Kudryavtseva EI, Markina NM, Kotlobay AA, Lukyanov SA, Zaraisky AG, Lukyanov KA
Citation:
Sci Rep. 2015 Jan 12;5:7729. doi: 10.1038/srep07729
Epub:
Not Epub
Abstract:
Nonsense-mediated mRNA decay (NMD) is a ubiquitous mechanism of degradation of transcripts with a premature termination codon....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pereverzev AP, Gurskaya NG, Ermakova GV, Kudryavtseva EI, Markina NM, Kotlobay AA, Lukyanov SA, Zaraisky AG, Lukyanov KA. Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level. Sci Rep. 2015 Jan 12;5:7729. doi: 10.1038/srep07729.

Notch3 establishes brain vascular integrity by regulating pericyte number

Authors:
Wang Y, Pan L, Moens CB, Appel B
Citation:
Development. 2014 Jan;141(2):307-17. doi: 10.1242/dev.096107. Epub 2013 Dec 4
Epub:
Not Epub
Abstract:
Brain pericytes are important regulators of brain vascular integrity, permeability and blood flow. Deficiencies of brain...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Pan L, Moens CB, Appel B. Notch3 establishes brain vascular integrity by regulating pericyte number. Development. 2014 Jan;141(2):307-17. doi: 10.1242/dev.096107. Epub 2013 Dec 4.

Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome

Authors:
Ben-Omran T, Fahiminiya S, Sorfazlian N, Almuriekhi M, Nawaz Z, Nadaf J, Khadija KA, Zaineddin S, Kamel H, Majewski J, Tropepe V
Citation:
J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2014-102707
Epub:
Yes
Abstract:
Background: Neuroanatomical defects are often present in children with severe developmental delay and intellectual disabilities...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ben-Omran T, Fahiminiya S, Sorfazlian N, Almuriekhi M, Nawaz Z, Nadaf J, Khadija KA, Zaineddin S, Kamel H, Majewski J, Tropepe V. Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome. J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2014-102707.

Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression

Authors:
Wong L, Power N, Miles A, Tropepe V
Citation:
Dev Biol. 2015 Apr 11. pii: S0012-1606(15)00171-2. doi: 10.1016/j.ydbio.2015.03.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Understanding the mechanisms that regulate the transition between the proliferative and a post-mitotic state of retinal...
Organism or Cell Type:
zebrafish
Citation Extract:
Wong L, Power N, Miles A, Tropepe V. Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression. Dev Biol. 2015 Apr 11. pii: S0012-1606(15)00171-2. doi: 10.1016/j.ydbio.2015.03.020. [Epub ahead of print].

An essential role for parathyroid hormone in gill formation and differentiation of ion-transporting cells in developing zebrafish

Authors:
Kwong RW, Perry SF
Citation:
Endocrinology. 2015 Apr 14:en20141968. [Epub ahead of print]
Epub:
Yes
Abstract:
In vertebrates, parathyroid hormone (PTH) is important for skeletogenesis and Ca2+ homeostasis. However, little is known about...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong RW, Perry SF. An essential role for parathyroid hormone in gill formation and differentiation of ion-transporting cells in developing zebrafish. Endocrinology. 2015 Apr 14:en20141968. [Epub ahead of print].

Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model

Authors:
Martins Metelo A, Noonan HR, Xiang L, Jin Y, Baker R, Kamentsky L, Zhang Y, van Rooijen E, Shin J, Carpenter AE, Yeh JR, Peterson RT, Iliopoulos O
Citation:
J Clin Invest. 2015 Apr 13. pii: 73665. doi: 10.1172/JCI73665. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Patients with a germline mutation in von Hippel-Lindau (VHL) develop renal cell cancers and hypervascular tumors of the brain,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Martins Metelo A, Noonan HR, Xiang L, Jin Y, Baker R, Kamentsky L, Zhang Y, van Rooijen E, Shin J, Carpenter AE, Yeh JR, Peterson RT, Iliopoulos O. Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model. J Clin Invest. 2015 Apr 13. pii: 73665. doi: 10.1172/JCI73665. [Epub ahead of print].

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Authors:
Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI
Citation:
J Exp Med. 2015;[Epub ahead of print] doi:10.1084/jem.20141528
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. J Exp Med. 2015;[Epub ahead of print] doi:10.1084/jem.20141528 .

Depletion of melanoma fn14 by oligonucleotide-mediated exon skipping

Authors:
KM Beck, S Ramaswami, W Zeng and MS Hayden
Citation:
J Invest Dermatol. 2015;135:S106–S113. doi:10.1038/jid.2015.77
Epub:
Not Epub
Abstract:
Fibroblast growth factor inducible 14 (Fn14) is the receptor for the TNF family cytokine TNF-like weak inducer of apoptosis (...
Organism or Cell Type:
cell culture: human melanoma cell lines
Citation Extract:
KM Beck, S Ramaswami, W Zeng and MS Hayden. Depletion of melanoma fn14 by oligonucleotide-mediated exon skipping. J Invest Dermatol. 2015;135:S106–S113. doi:10.1038/jid.2015.77.

Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function

Authors:
Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, Yan X
Citation:
PLoS One. 2015 Apr 10;10(4):e0124378. doi: 10.1371/journal.pone.0124378. eCollection 2015
Epub:
Not Epub
Abstract:
Cilia formation and function require a special set of trafficking machinery termed intraflagellar transport (IFT), consisting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, Yan X. Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function. PLoS One. 2015 Apr 10;10(4):e0124378. doi: 10.1371/journal.pone.0124378. eCollection 2015.

The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output

Authors:
Yvette Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis A-PG, Hart D, Fischle W, Divecha N
Citation:
Molec Cell. 2015;[Epub ahead of print] doi:10.1016/j.molcel.2015.03.009
Epub:
Yes
Abstract:
Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yvette Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis A-PG, Hart D, Fischle W, Divecha N. The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output. Molec Cell. 2015;[Epub ahead of print] doi:10.1016/j.molcel.2015.03.009.

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