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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development
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Citation:
FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5 Epub:
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The bone morphogenetic protein (BMP) signaling pathways have important roles in embryonic development and cellular homeostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holtzhausen A, Golzio C, How T, Lee YH, Schiemann WP, Katsanis N, Blobe GC. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5. |
Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish
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Citation:
Basic Res Cardiol. 2015 Mar;110(2):14. doi: 10.1007/s00395-015-0468-7. Epub 2015 Feb 20 Epub:
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The genetic underpinnings of heart rate regulation are only poorly understood. In search for genetic regulators of cardiac... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Keßler M, Berger IM, Just S, Rottbauer W. Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish. Basic Res Cardiol. 2015 Mar;110(2):14. doi: 10.1007/s00395-015-0468-7. Epub 2015 Feb 20. |
Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth
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Citation:
Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13 Epub:
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The liver and pancreas arise from common endodermal progenitors. How these distinct cell fates are specified is poorly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13. |
A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease
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Citation:
PLoS Genet. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169. eCollection 2015 Apr Epub:
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Inherited neurodegenerative disorders are debilitating diseases that occur across different species. We have performed clinical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen TS, Seppälä EH, Becker D, Drögemüller M, Dietschi E, Drögemüller C, Lang J, Steffen F, Rohdin C, Jäderlund KH, Lappalainen AK, Hahn K, Wohlsein P, Baumgärtner W, Henke D, Oevermann A, Kere J, Lohi H, Leeb T. A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease. PLoS Genet. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169. eCollection 2015 Apr. |
Quantitative Analysis of PMLA Nanoconjugate Components after Backbone Cleavage
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Citation:
Int J Mol Sci. 2015;16(4):8607-20. doi:10.3390/ijms16048607 Epub:
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Multifunctional polymer nanoconjugates containing multiple components show great promise in cancer therapy, but in most cases... Delivery Method:
nanoparticle Citation Extract: Ding H, Patil R, Portilla-Arias J, Black KL, Ljubimova JY, Eggehard Holler E. Quantitative Analysis of PMLA Nanoconjugate Components after Backbone Cleavage. Int J Mol Sci. 2015;16(4):8607-20. doi:10.3390/ijms16048607. |
Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo
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Citation:
Elife. 2015 Apr 15;4. doi: 10.7554/eLife.05279 Epub:
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Cell migration and polarization is controlled by signals in the environment. Migrating cells typically form filopodia that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meyen D, Tarbashevich K, Banisch TU, Wittwer C, Reichman-Fried M, Maugis B, Grimaldi C, Messerschmidt EM, Raz E. Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo. Elife. 2015 Apr 15;4. doi: 10.7554/eLife.05279. |
Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity
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Citation:
Dev Biol. 2014 Feb 15;386(2):302-7. doi: 10.1016/j.ydbio.2013.12.035. Epub 2013 Dec 31 Epub:
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The oral-aboral axis of the sea urchin embryo is specified conditionally via a regulated feedback circuit involving the... Delivery Method:
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Strongylocentrotus purpuratus (sea urchin) Citation Extract: Coffman JA, Wessels A, DeSchiffart C, Rydlizky K. Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity. Dev Biol. 2014 Feb 15;386(2):302-7. doi: 10.1016/j.ydbio.2013.12.035. Epub 2013 Dec 31. |
Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers
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Citation:
Dev Biol. 2014 Feb 15;386(2):461-72. doi: 10.1016/j.ydbio.2013.12.010. Epub 2013 Dec 17 Epub:
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Neural crest development is orchestrated by a complex and still poorly understood gene regulatory network. Premigratory neural... Delivery Method:
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Xenopus laevis Citation Extract: Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH. Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers. Dev Biol. 2014 Feb 15;386(2):461-72. doi: 10.1016/j.ydbio.2013.12.010. Epub 2013 Dec 17. |
Nanoscale imaging of caveolin-1 membrane domains in vivo
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Citation:
PLoS One. 2015 Feb 3;10(2):e0117225. doi: 10.1371/journal.pone.0117225. eCollection 2015 Epub:
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Light microscopy enables noninvasive imaging of fluorescent species in biological specimens, but resolution is generally... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gabor KA, Kim D, Kim CH, Hess ST. Nanoscale imaging of caveolin-1 membrane domains in vivo. PLoS One. 2015 Feb 3;10(2):e0117225. doi: 10.1371/journal.pone.0117225. eCollection 2015. |
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells
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Citation:
Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E420-9. doi: 10.1073/pnas.1424576112. Epub 2015 Jan 20 Epub:
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Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E420-9. doi: 10.1073/pnas.1424576112. Epub 2015 Jan 20. |