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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing

Authors:
Rosowski EE, Raffa N, Knox BP, Golenberg N, Keller NP, Huttenlocher A
Citation:
PLoS Pathog. 2018 Aug 2;14(8):e1007229. doi: 10.1371/journal.ppat.1007229. eCollection 2018 Aug
Epub:
Not Epub
Abstract:
In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosowski EE, Raffa N, Knox BP, Golenberg N, Keller NP, Huttenlocher A. Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. PLoS Pathog. 2018 Aug 2;14(8):e1007229. doi: 10.1371/journal.ppat.1007229. eCollection 2018 Aug.

De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism

Authors:
Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y
Citation:
Am J Hum Genet. 2018 Aug 6. pii: S0002-9297(18)30246-5. doi: 10.1016/j.ajhg.2018.07.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Neurodevelopment is a transcriptionally orchestrated process. Cyclin K, a regulator of transcription encoded by CCNK, is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y. De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism. Am J Hum Genet. 2018 Aug 6. pii: S0002-9297(18)30246-5. doi: 10.1016/j.ajhg.2018.07.019. [Epub ahead of print].

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

Authors:
Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S
Citation:
Elife. 2018 Jul 31;7. pii: e36953. doi: 10.7554/eLife.36953
Epub:
Not Epub
Abstract:
Signaling filopodia, termed cytonemes, are dynamic actin-based membrane structures that regulate the exchange of signaling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates. Elife. 2018 Jul 31;7. pii: e36953. doi: 10.7554/eLife.36953.

Xbra and Smad-1 cooperate to activate the transcription of neural repressor ventx1.1 in Xenopus embryos

Authors:
Kumar S, Umair Z, Yoon J, Lee U, Kim SC, Park JB, Lee JY, Kim J
Citation:
Sci Rep. 2018 Jul 30;8(1):11391. doi: 10.1038/s41598-018-29740-9
Epub:
Not Epub
Abstract:
Crosstalk of signaling pathways play crucial roles in cell proliferation, cell differentiation, and cell fate determination for...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kumar S, Umair Z, Yoon J, Lee U, Kim SC, Park JB, Lee JY, Kim J. Xbra and Smad-1 cooperate to activate the transcription of neural repressor ventx1.1 in Xenopus embryos. Sci Rep. 2018 Jul 30;8(1):11391. doi: 10.1038/s41598-018-29740-9.

MTG1 couples mitoribosome large subunit assembly with intersubunit bridge formation

Authors:
Kim HJ, Barrientos A
Citation:
Nucleic Acids Res. 2018 Jul 31. doi: 10.1093/nar/gky672. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian mitochondrial ribosomes (mitoribosomes) synthesize 13 proteins, essential components of the oxidative phosphorylation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim HJ, Barrientos A. MTG1 couples mitoribosome large subunit assembly with intersubunit bridge formation. Nucleic Acids Res. 2018 Jul 31. doi: 10.1093/nar/gky672. [Epub ahead of print].

An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae

Authors:
Sun P, Zhang Y, Zhao F, Wu J-P, Pun SH, Peng C, Du M, Vai MI, Liu D, Chen F
Citation:
Front Cell Neurosci. 2018 Aug 21;12:257. doi: 10.3389/fncel.2018.00257. eCollection 2018.
Epub:
Yes
Abstract:
Zebrafish (Danio rerio) larvae are widely used to study otic functions because they possess all five typical vertebrate senses...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun P, Zhang Y, Zhao F, Wu J-P, Pun SH, Peng C, Du M, Vai MI, Liu D, Chen F. An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae. Front Cell Neurosci. 2018 Aug 21;12:257. doi: 10.3389/fncel.2018.00257. eCollection 2018. .

The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis

Authors:
Modepalli V, Fridrich A, Agron M, Moran Y
Citation:
PLoS Genet. 2018 Aug 17;14(8):e1007590. doi: 10.1371/journal.pgen.1007590. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Small non-coding RNAs (sRNAs) such as microRNAs (miRNAs), small interfering RNAs (siRNAs) and piwi-interacting RNAs (piRNAs)...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Modepalli V, Fridrich A, Agron M, Moran Y. The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis. PLoS Genet. 2018 Aug 17;14(8):e1007590. doi: 10.1371/journal.pgen.1007590. [Epub ahead of print].

A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease

Authors:
Li S, Liu S, Chen W, Yuan Y, Gu R, Song Y, Li J, Cao Y, Lin Y, Xu J, Wang H, Ma D, Ma X, Sheng W, Huang G
Citation:
Sci Rep. 2018 Aug 17;8(1):12386. doi: 10.1038/s41598-018-30204-3
Epub:
Not Epub
Abstract:
Heterotaxy syndrome (HTX) is characterized by left-right (LR) asymmetry disturbances associated with severe heart malformations...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li S, Liu S, Chen W, Yuan Y, Gu R, Song Y, Li J, Cao Y, Lin Y, Xu J, Wang H, Ma D, Ma X, Sheng W, Huang G. A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease. Sci Rep. 2018 Aug 17;8(1):12386. doi: 10.1038/s41598-018-30204-3.

Inhibiting neutral amino acid transport for the treatment of phenylketonuria

Authors:
Belanger AM, Przybylska M, Gefteas E, Furgerson M, Geller S, Kloss A, Cheng SH, Zhu Y, Yew NS
Citation:
JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The neuropathological effects of phenylketonuria (PKU) stem from the inability of the body to metabolize excess phenylalanine (...
Delivery Method:
Endo-Porter in culture, peptide-linked in mice
Organism or Cell Type:
cell culture: primary mouse renal tubular epithelial cells, mice
Citation Extract:
Belanger AM, Przybylska M, Gefteas E, Furgerson M, Geller S, Kloss A, Cheng SH, Zhu Y, Yew NS. Inhibiting neutral amino acid transport for the treatment of phenylketonuria. JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. [Epub ahead of print].

Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking

Authors:
Kondo Y, Fu J, Wang H, Hoover C, McDaniel JM, Steet R, Patra D, Song J, Pollard L, Cathey S, Yago T, Wiley G, Macwana S, Guthridge J, McGee S, Li S, Griffin C, Furukawa K, James JA, Ruan C, McEver RP, Wierenga KJ, Gaffney PM, Xia L
Citation:
JCI Insight. 2018 Jul 26;3(14). pii: 121596. doi: 10.1172/jci.insight.121596. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Site-1 protease (S1P), encoded by MBTPS1, is a serine protease in the Golgi. S1P regulates lipogenesis, endoplasmic reticulum (...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human primary fibroblasts, immortalized
Citation Extract:
Kondo Y, Fu J, Wang H, Hoover C, McDaniel JM, Steet R, Patra D, Song J, Pollard L, Cathey S, Yago T, Wiley G, Macwana S, Guthridge J, McGee S, Li S, Griffin C, Furukawa K, James JA, Ruan C, McEver RP, Wierenga KJ, Gaffney PM, Xia L. Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking. JCI Insight. 2018 Jul 26;3(14). pii: 121596. doi: 10.1172/jci.insight.121596. [Epub ahead of print].

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