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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development

Authors:
Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke AS
Citation:
PLoS Genet. 2018;14(3):e1007278. doi:10.1371/journal.pgen.1007278
Epub:
Not Epub
Abstract:
Opacification of the ocular lens, termed cataract, is a common cause of blindness. To become transparent, lens fiber cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish, Xenopus laevis
Citation Extract:
Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke AS. The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS Genet. 2018;14(3):e1007278. doi:10.1371/journal.pgen.1007278.

Molybdenum Disulfide Field-Effect Transistor Biosensor for Ultrasensitive Detection of DNA by Employing Morpholino as Probe

Authors:
Mei J, Li Y-T, Zhang H, Xiao M-M, Ning Y, Zhang Z-Y, Zhang G-J
Citation:
Biosens Bioelectr. 2018;{Epub ahead of print] doi:10.1016/j.bios.2018.03.043
Epub:
Yes
Abstract:
This work reports on a molybdenum disulfide (MoS2) based field-effect transistor (FET) biosensor for ultrasensitive label-free...
Citation Extract:
Mei J, Li Y-T, Zhang H, Xiao M-M, Ning Y, Zhang Z-Y, Zhang G-J. Molybdenum Disulfide Field-Effect Transistor Biosensor for Ultrasensitive Detection of DNA by Employing Morpholino as Probe. Biosens Bioelectr. 2018;{Epub ahead of print] doi:10.1016/j.bios.2018.03.043.

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects

Authors:
Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP
Citation:
Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901
Epub:
Yes
Abstract:
BACKGROUND: Inhibition of PKC-α (protein kinase C-α) enhances contractility and cardioprotection in animal models, but effects...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP. Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects. Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901.

Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos

Authors:
Cutler CP, Tanner P
Citation:
The Bulletin: Mount Desert Island Biological Laboratory. 2014;53:12-13
Epub:
Not Epub
Abstract:
Vivo-morpholinos are artificial nucleic acids that can block the protein production from a particular gene. Direct intestinal...
Delivery Method:
Vivo-morpholino
Organism or Cell Type:
Anguilla rostrata (American eel)
Citation Extract:
Cutler CP, Tanner P. Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos. The Bulletin: Mount Desert Island Biological Laboratory. 2014;53:12-13.

March2 is required for head formation by mediating Dishevelled degradation in concert with Dapper1

Authors:
Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK
Citation:
Development. 2018 Mar 16. pii: dev.143107. doi: 10.1242/dev.143107. [Epub ahead of print]
Epub:
Yes
Abstract:
Dishevelled (Dvl/Dsh) is a key scaffold protein that propagates Wnt signaling essential for embryogenesis and homeostasis....
Organism or Cell Type:
Xenopus
Citation Extract:
Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK. March2 is required for head formation by mediating Dishevelled degradation in concert with Dapper1. Development. 2018 Mar 16. pii: dev.143107. doi: 10.1242/dev.143107. [Epub ahead of print].

Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo

Authors:
Sepúlveda-Ramírez SP, Toledo-Jacobo L, Henson JH, Shuster CB
Citation:
Dev Biol. 2018 Mar 16. pii: S0012-1606(17)30779-0. doi: 10.1016/j.ydbio.2018.03.015. [Epub ahead of print]
Epub:
Yes
Abstract:
In the sea urchin embryo, gastrulation is characterized by the ingression and directed cell migration of primary mesenchyme...
Organism or Cell Type:
sea urchin
Citation Extract:
Sepúlveda-Ramírez SP, Toledo-Jacobo L, Henson JH, Shuster CB. Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo. Dev Biol. 2018 Mar 16. pii: S0012-1606(17)30779-0. doi: 10.1016/j.ydbio.2018.03.015. [Epub ahead of print].

An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization

Authors:
Dobrzycki T, Krecsmarik M, Bonkhofer F, Patient R, Monteiro R
Citation:
Biol Open. 2018 Mar 13. pii: bio.031096. doi: 10.1242/bio.031096. [Epub ahead of print]
Epub:
Yes
Abstract:
Advances in genome engineering have resulted in the generation of numerous zebrafish mutant lines. A commonly used method to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dobrzycki T, Krecsmarik M, Bonkhofer F, Patient R, Monteiro R. An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization. Biol Open. 2018 Mar 13. pii: bio.031096. doi: 10.1242/bio.031096. [Epub ahead of print].

Dynamics of two key maternal factors that initiate zygotic regulatory programs in ascidian embryos

Authors:
Oda-Ishii I, Abe T, Satou Y
Citation:
Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30031-9. doi: 10.1016/j.ydbio.2018.03.009. [Epub ahead of print]
Epub:
Yes
Abstract:
In animal embryos, transcription is repressed for a definite period of time after fertilization. In the embryo of the ascidian...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Oda-Ishii I, Abe T, Satou Y. Dynamics of two key maternal factors that initiate zygotic regulatory programs in ascidian embryos. Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30031-9. doi: 10.1016/j.ydbio.2018.03.009. [Epub ahead of print].

Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics

Authors:
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, Tambalo M, Bosc C, Mailly P, Revenu C, Peris L, Bolte S, Schneider-Maunoury S, Houart C, Nothias F, Larcher JC, Andrieux A, Hazan J
Citation:
J Cell Biol. 2018 Mar 13. pii: jcb.201604108. doi: 10.1083/jcb.201604108. [Epub ahead of print]
Epub:
Yes
Abstract:
During neural circuit assembly, extrinsic signals are integrated into changes in growth cone (GC) cytoskeleton underlying axon...
Organism or Cell Type:
zebrafish
Citation Extract:
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, Tambalo M, Bosc C, Mailly P, Revenu C, Peris L, Bolte S, Schneider-Maunoury S, Houart C, Nothias F, Larcher JC, Andrieux A, Hazan J. Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics. J Cell Biol. 2018 Mar 13. pii: jcb.201604108. doi: 10.1083/jcb.201604108. [Epub ahead of print].

TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development

Authors:
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA
Citation:
Cell Rep. 2018 Mar 13;22(11):2964-2977. doi: 10.1016/j.celrep.2018.02.066
Epub:
Not Epub
Abstract:
Cysteine cathepsins play roles during development and disease beyond their function in lysosomal protein turnover. Here, we...
Organism or Cell Type:
zebrafish
Citation Extract:
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA. TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development. Cell Rep. 2018 Mar 13;22(11):2964-2977. doi: 10.1016/j.celrep.2018.02.066.

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