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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Morpholino-Mediated Exon Skipping Targeting Human ACVR1/ALK2 for Fibrodysplasia Ossificans Progressiva
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Citation:
Methods Mol Biol. 2018;1828:497-502. doi: 10.1007/978-1-4939-8651-4_32 Epub:
Not Epub Abstract:
Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal-dominant disorder characterized by progressive heterotopic... Organism or Cell Type:
cell culture: Fibrodysplasia ossificans progressiva human primary cells Citation Extract: Maruyama R, Yokota T. Morpholino-Mediated Exon Skipping Targeting Human ACVR1/ALK2 for Fibrodysplasia Ossificans Progressiva. Methods Mol Biol. 2018;1828:497-502. doi: 10.1007/978-1-4939-8651-4_32. |
Exon Skipping by Ultrasound-Enhanced Delivery of Morpholino with Bubble Liposomes for Myotonic Dystrophy Model Mice
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Citation:
Methods Mol Biol. 2018;1828:481-487. doi: 10.1007/978-1-4939-8651-4_30 Epub:
Not Epub Abstract:
Abnormal splicing of the chloride channel 1 (CLCN1) gene causes myotonic dystrophy type 1 (DM1). Therefore, controlling the... Delivery Method:
bubble liposome ultrasonic Organism or Cell Type:
mice Citation Extract: Negishi Y, Endo-Takahashi Y, Ishiura S. Exon Skipping by Ultrasound-Enhanced Delivery of Morpholino with Bubble Liposomes for Myotonic Dystrophy Model Mice. Methods Mol Biol. 2018;1828:481-487. doi: 10.1007/978-1-4939-8651-4_30. |
Morpholino-Mediated Exon Inclusion for SMA
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Citation:
Methods Mol Biol. 2018;1828:467-477. doi: 10.1007/978-1-4939-8651-4_29 Epub:
Not Epub Abstract:
The application of antisense oligonucleotides (AONs) to modify pre-messenger RNA splicing has great potential for treating... Organism or Cell Type:
mice SMA Citation Extract: Zhou H, Muntoni F. Morpholino-Mediated Exon Inclusion for SMA. Methods Mol Biol. 2018;1828:467-477. doi: 10.1007/978-1-4939-8651-4_29. |
Systemic and ICV Injections of Antisense Oligos into SMA Mice and Evaluation
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Citation:
Methods Mol Biol. 2018;1828:455-465. doi: 10.1007/978-1-4939-8651-4_28 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is the most common genetic cause of infantile death caused by mutations in the SMN1 gene.... Organism or Cell Type:
mice severe SMA model Citation Extract: Aslesh T, Maruyama R, Yokota T. Systemic and ICV Injections of Antisense Oligos into SMA Mice and Evaluation. Methods Mol Biol. 2018;1828:455-465. doi: 10.1007/978-1-4939-8651-4_28. |
In Vitro Evaluation of Antisense-Mediated Exon Inclusion for Spinal Muscular Atrophy
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Citation:
Methods Mol Biol. 2018;1828:439-454. doi: 10.1007/978-1-4939-8651-4_27 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA), the most common gentic cause of infantile death caused by mutations in the SMN1 gene, presents a... Organism or Cell Type:
cell culture: type I SMA patient fibroblast cell lines Citation Extract: Touznik A, Maruyama R, Yokota T. In Vitro Evaluation of Antisense-Mediated Exon Inclusion for Spinal Muscular Atrophy. Methods Mol Biol. 2018;1828:439-454. doi: 10.1007/978-1-4939-8651-4_27. |
In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs
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Citation:
Methods Mol Biol. 2018;1828:365-379. doi: 10.1007/978-1-4939-8651-4_23 Epub:
Not Epub Abstract:
Exon skipping is an emerging approach to treating Duchenne muscular dystrophy (DMD), one of the most common lethal genetic... Delivery Method:
peptide-linked Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Maruyama R, Aoki Y, Takeda S, Yokota T. In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs. Methods Mol Biol. 2018;1828:365-379. doi: 10.1007/978-1-4939-8651-4_23. |
A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers
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Citation:
Methods Mol Biol. 2018;1828:293-306. doi: 10.1007/978-1-4939-8651-4_18 Epub:
Not Epub Abstract:
Morpholino oligomers have great therapeutic potential for treatment of a broad range of human diseases, including viral,... Delivery Method:
peptide-linked Organism or Cell Type:
zebrafish Citation Extract: Kim J, Clark K, Barton C, Tanguay R, Moulton H. A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers. Methods Mol Biol. 2018;1828:293-306. doi: 10.1007/978-1-4939-8651-4_18. |
In Vivo Evaluation of Single-Exon and Multiexon Skipping in mdx52 Mice
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Citation:
Methods Mol Biol. 2018;1828:275-292. doi: 10.1007/978-1-4939-8651-4_17 Epub:
Not Epub Abstract:
Exon-skipping therapy is an emerging approach that uses synthetic DNA-like molecules called antisense oligonucleotides (ASOs)... Organism or Cell Type:
mice mdx52 Citation Extract: Mizobe Y, Miyatake S, Takizawa H, Hara Y, Yokota T, Nakamura A, Takeda S, Aoki Y. In Vivo Evaluation of Single-Exon and Multiexon Skipping in mdx52 Mice. Methods Mol Biol. 2018;1828:275-292. doi: 10.1007/978-1-4939-8651-4_17. |
Systemic Injection of Peptide-PMOs into Humanized DMD Mice and Evaluation by RT-PCR and ELISA
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Citation:
Methods Mol Biol. 2018;1828:263-273. doi: 10.1007/978-1-4939-8651-4_16 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder due to the lack of dystrophin production. The disease is... Delivery Method:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_16 Organism or Cell Type:
mice Citation Extract: Melo D, Maruyama R, Yokota T. Systemic Injection of Peptide-PMOs into Humanized DMD Mice and Evaluation by RT-PCR and ELISA. Methods Mol Biol. 2018;1828:263-273. doi: 10.1007/978-1-4939-8651-4_16. |
Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment
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Citation:
Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13 Epub:
Not Epub Abstract:
Duplications of one or more dystrophin exons that disrupt the reading frame account for about 15% of all Duchenne cases, and... Delivery Method:
peptide-linked Citation Extract: Greer K, Fletcher S, Wilton SD. Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment. Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13. |