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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Mir-126 is a conserved modulator of lymphatic development

Authors:
Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR
Citation:
Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30138-6. doi: 10.1016/j.ydbio.2018.03.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Organ homeostasis relies upon cellular and molecular processes that restore tissue structure and function in a timely fashion....
Organism or Cell Type:
zebrafish
Citation Extract:
Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR. Mir-126 is a conserved modulator of lymphatic development. Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30138-6. doi: 10.1016/j.ydbio.2018.03.006. [Epub ahead of print].

Analysis of hpf1 expression and function in early embryonic development of zebrafish

Authors:
Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y
Citation:
Dev Genes Evol. 2018 Mar 17. doi: 10.1007/s00427-018-0608-9. [Epub ahead of print]
Epub:
Yes
Abstract:
About 70% of zebrafish (Danio rerio) genes are orthologues of the human's, which are of great interests, but still largely...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y. Analysis of hpf1 expression and function in early embryonic development of zebrafish. Dev Genes Evol. 2018 Mar 17. doi: 10.1007/s00427-018-0608-9. [Epub ahead of print].

Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo

Authors:
Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M
Citation:
Development. 2018 Mar 12;145(5). pii: dev159640. doi: 10.1242/dev.159640
Epub:
Not Epub
Abstract:
The homeodomain transcription factor Otx2 has essential roles in head and eye formation via the negative and positive...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M. Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo. Development. 2018 Mar 12;145(5). pii: dev159640. doi: 10.1242/dev.159640.

Time-lapse observation of stepwise regression of Erk activity in zebrafish presomitic mesoderm

Authors:
Sari DWK, Akiyama R, Naoki H, Ishijima H, Bessho Y, Matsui T
Citation:
Sci Rep. 2018 Mar 12;8(1):4335. doi: 10.1038/s41598-018-22619-9
Epub:
Not Epub
Abstract:
During somite segmentation, clock genes oscillate within the posterior presomitic mesoderm (PSM). The temporal information ties...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sari DWK, Akiyama R, Naoki H, Ishijima H, Bessho Y, Matsui T. Time-lapse observation of stepwise regression of Erk activity in zebrafish presomitic mesoderm. Sci Rep. 2018 Mar 12;8(1):4335. doi: 10.1038/s41598-018-22619-9.

GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys

Authors:
Romaus-Sanjurjo D, Ledo-Garcia R, Fernandez-Lopez B, Hanslik K, Morgan JR, Barreiro-Iglesias A, Rodicio MC
Citation:
bioRxiv. 2018:[preprint] doi:10.1101/280891
Epub:
Yes
Abstract:
In mammals, spinal cord injury (SCI) causes permanent disability. The poor regenerative capacity of descending neurons is one...
Delivery Method:
Gelfoam at lesion
Organism or Cell Type:
Petromyzon marinus (lamprey)
Citation Extract:
Romaus-Sanjurjo D, Ledo-Garcia R, Fernandez-Lopez B, Hanslik K, Morgan JR, Barreiro-Iglesias A, Rodicio MC. GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys. bioRxiv. 2018:[preprint] doi:10.1101/280891 .

Polycystin-1 loss-of-function is directly linked to an imbalance in G-Protein signaling in the kidney

Authors:
Zhang B, Tran U, Wessely O
Citation:
Development. 2018 Mar 12. pii: dev.158931. doi: 10.1242/dev.158931. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The development of the kidney relies on the establishment and maintenance of a precise tubular diameter of its functional units...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang B, Tran U, Wessely O. Polycystin-1 loss-of-function is directly linked to an imbalance in G-Protein signaling in the kidney. Development. 2018 Mar 12. pii: dev.158931. doi: 10.1242/dev.158931. [Epub ahead of print].

A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations

Authors:
Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W
Citation:
Neuromusc Disord. 2018;[Epub ahead of print] doi:10.1016/j.nmd.2018.03.001
Epub:
Yes
Abstract:
Missense mutations in the four and a half LIM domain 1 (FHL1) gene were found to cause X-linked inherited myopathies of both...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W. A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations. Neuromusc Disord. 2018;[Epub ahead of print] doi:10.1016/j.nmd.2018.03.001.

TBX20 Regulates Angiogenesis Through the PROK2-PROKR1 Pathway

Authors:
Meng S, Gu Q, Yang X, Lv J, Owusu I, Matrone G, Chen K, Cooke JP, Fang L
Citation:
Circulation. 2018 Mar 15. pii: CIRCULATIONAHA.118.033939. doi: 10.1161/CIRCULATIONAHA.118.033939. [Epub ahead of print]
Epub:
Yes
Abstract:
Background -Angiogenesis is integral for embryogenesis, and targeting angiogenesis improves the outcome of many pathological...
Organism or Cell Type:
zebrafish
Citation Extract:
Meng S, Gu Q, Yang X, Lv J, Owusu I, Matrone G, Chen K, Cooke JP, Fang L. TBX20 Regulates Angiogenesis Through the PROK2-PROKR1 Pathway. Circulation. 2018 Mar 15. pii: CIRCULATIONAHA.118.033939. doi: 10.1161/CIRCULATIONAHA.118.033939. [Epub ahead of print].

Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling

Authors:
Jin Y, Weinstein DC
Citation:
Dev Biol. 2018 Mar 9. pii: S0012-1606(17)30225-7. doi: 10.1016/j.ydbio.2018.03.008. [Epub ahead of print]
Epub:
Yes
Abstract:
The cement gland in Xenopus laevis has long been used as a model to study the interplay of cell signaling and transcription...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jin Y, Weinstein DC. Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling. Dev Biol. 2018 Mar 9. pii: S0012-1606(17)30225-7. doi: 10.1016/j.ydbio.2018.03.008. [Epub ahead of print].

Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway

Authors:
Xu D, Lv J, He L, Fu L, Hu R, Cao Y, Mei C
Citation:
FASEB J. 2018 Mar 12:fj201701376RR. doi: 10.1096/fj.201701376RR. [Epub ahead of print]
Epub:
Yes
Abstract:
Polarity complexes, including the PAR (Partitioning-defective), CRB (Crumbs) and SCRIB (Scribble) complexes, are required for...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu D, Lv J, He L, Fu L, Hu R, Cao Y, Mei C. Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway. FASEB J. 2018 Mar 12:fj201701376RR. doi: 10.1096/fj.201701376RR. [Epub ahead of print].

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