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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

Retinoic acid induced expression of Hnf1β and Fzd4 is required for pancreas development in Xenopus laevis

Authors:
Gere MB, Pommerenke C, Lingner T, Pieler T
Citation:
Development. 2018 May 16. pii: dev.161372. doi: 10.1242/dev.161372. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid (RA) is required for pancreas specification in Xenopus and other vertebrates. However, the gene network that is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gere MB, Pommerenke C, Lingner T, Pieler T. Retinoic acid induced expression of Hnf1β and Fzd4 is required for pancreas development in Xenopus laevis. Development. 2018 May 16. pii: dev.161372. doi: 10.1242/dev.161372. [Epub ahead of print].

Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio.

Authors:
Edie S, Zaghloul NA, Leitch CC, Klinedinst DK, Lebron J, Thole JF, McCallion AS, Katsanis N, Reeves RH
Citation:
G3 (Bethesda). 2018 May 14. pii: g3.200144.2018. doi: 10.1534/g3.118.200144. [Epub ahead of print]
Epub:
Yes
Abstract:
Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS), one of the most genetically complex conditions...
Organism or Cell Type:
zebrafish
Citation Extract:
Edie S, Zaghloul NA, Leitch CC, Klinedinst DK, Lebron J, Thole JF, McCallion AS, Katsanis N, Reeves RH. Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio. . G3 (Bethesda). 2018 May 14. pii: g3.200144.2018. doi: 10.1534/g3.118.200144. [Epub ahead of print] .

Role of calcium-sensing receptor in mechanotransducer-channel-mediated Ca2+ influx in hair cells of zebrafish larvae

Authors:
Lin L-Y, Yeh Y-H, Hung G-Y, Lin C-H, Hwang P-P, Horng J-L
Citation:
Front Physiol. 2018;[Epub] doi:10.3389/fphys.2018.00649
Epub:
Not Epub
Abstract:
The calcium-sensing receptor (CaSR) is an extracellular Ca2+ sensor that plays a critical role in maintaining Ca2+ homeostasis...
Organism or Cell Type:
zebrafish
Citation Extract:
Lin L-Y, Yeh Y-H, Hung G-Y, Lin C-H, Hwang P-P, Horng J-L. Role of calcium-sensing receptor in mechanotransducer-channel-mediated Ca2+ influx in hair cells of zebrafish larvae. Front Physiol. 2018;[Epub] doi:10.3389/fphys.2018.00649 .

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132

Authors:
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI
Citation:
Proc Natl Acad Sci U S A. 2018 Aug 23. pii: 201806077. doi: 10.1073/pnas.1806077115. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Epoxyeicosatrienoic acids (EETs) are lipid-derived signaling molecules with cardioprotective and vasodilatory actions. We...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proc Natl Acad Sci U S A. 2018 Aug 23. pii: 201806077. doi: 10.1073/pnas.1806077115. [Epub ahead of print].

The N-terminal domain of gastrulation brain homeobox 2 (Gbx2) is required for iridophore specification in zebrafish

Authors:
Hozumi S, Shirai M, Wang J, Aoki S, Kikuchi Y
Citation:
Biochem Biophys Res Commun. 2018 May 19. pii: S0006-291X(18)31197-5. doi: 10.1016/j.bbrc.2018.05.128. [Epub ahead of print]
Epub:
Yes
Abstract:
Although body color pattern formation by pigment cells plays critical roles in animals, pigment cell specification has not yet...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hozumi S, Shirai M, Wang J, Aoki S, Kikuchi Y. The N-terminal domain of gastrulation brain homeobox 2 (Gbx2) is required for iridophore specification in zebrafish. Biochem Biophys Res Commun. 2018 May 19. pii: S0006-291X(18)31197-5. doi: 10.1016/j.bbrc.2018.05.128. [Epub ahead of print].

β-Catenin-dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria

Authors:
Pukhlyakova E, Aman AJ, Elsayad K, Technau U
Citation:
Proc Natl Acad Sci U S A. 2018 May 21. pii: 201713682. doi: 10.1073/pnas.1713682115. [Epub ahead of print]
Epub:
Yes
Abstract:
Although the genetic regulation of cellular differentiation processes is well established, recent studies have revealed the...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Pukhlyakova E, Aman AJ, Elsayad K, Technau U. β-Catenin-dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201713682. doi: 10.1073/pnas.1713682115. [Epub ahead of print].

Heart enhancers with deeply conserved regulatory activity are established early in development

Authors:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD
Citation:
Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z
Epub:
Not Epub
Abstract:
During the phylotypic period, embryos from different genera show similar gene expression patterns, implying common regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD. Heart enhancers with deeply conserved regulatory activity are established early in development. Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z.

Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish

Authors:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S
Citation:
Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May
Epub:
Not Epub
Abstract:
Objective: DEPDC5 was identified as a major genetic cause of focal epilepsy with deleterious mutations found in a wide range of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S. Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish. Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May.

Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish

Authors:
Berrun A, Harris E, Stachura DL
Citation:
PLoS One. 2018 May 14;13(5):e0196872. doi: 10.1371/journal.pone.0196872. eCollection 2018
Epub:
Not Epub
Abstract:
Hematopoiesis is an essential and highly regulated biological process that begins with hematopoietic stem cells (HSCs). In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berrun A, Harris E, Stachura DL. Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish. PLoS One. 2018 May 14;13(5):e0196872. doi: 10.1371/journal.pone.0196872. eCollection 2018.

Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish

Authors:
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran MC, Sittaramane V, Chandrasekhar A
Citation:
Mech Dev. 2018 May 16. pii: S0925-4773(18)30082-0. doi: 10.1016/j.mod.2018.05.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Contactin2 (Cntn2)/Transient Axonal Glycoprotein 1 (Tag1), a neural cell adhesion molecule, has established roles in neuronal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran MC, Sittaramane V, Chandrasekhar A. Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish. Mech Dev. 2018 May 16. pii: S0925-4773(18)30082-0. doi: 10.1016/j.mod.2018.05.005. [Epub ahead of print].

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