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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

CTP synthase knockdown during early development distorts the nascent vertebral column and causes fluid retention in multiple tissues in zebrafish

Authors:
Dzaki N, Wahab W, Azlan A, Azzam G
Citation:
Biochem Biophys Res Commun. 2018 Sep 18. pii: S0006-291X(18)31999-5. doi: 10.1016/j.bbrc.2018.09.074. [Epub ahead of print]
Epub:
Yes
Abstract:
CTP Synthase (CTPS) is a metabolic enzyme that is recognized as a catalyst for nucleotide, phospholipid and sialoglycoprotein...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X18319995
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dzaki N, Wahab W, Azlan A, Azzam G. CTP synthase knockdown during early development distorts the nascent vertebral column and causes fluid retention in multiple tissues in zebrafish. Biochem Biophys Res Commun. 2018 Sep 18. pii: S0006-291X(18)31999-5. doi: 10.1016/j.bbrc.2018.09.074. [Epub ahead of print].

Perturbations of BMP/TGF-β and VEGF/VEGFR signalling pathways in non-syndromic sporadic brain arteriovenous malformations (BAVM)

Authors:
Wang K, Zhao S, Liu B, Zhang Q, Li Y, Liu J, Shen Y, Ding X, Lin J, Wu Y, Yan Z, Chen J, Li X, Song X, Niu Y, Liu J, Chen W, Ming Y, Du R, Chen C, Long B, Zhang Y, Tong X, Zhang S, Posey JE, Zhang B, Wu Z, Wythe JD, Liu P, Lupski JR, Yang X, Wu N
Citation:
J Med Genet. 2018 Aug 17. pii: jmedgenet-2017-105224. doi: 10.1136/jmedgenet-2017-105224. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Brain arteriovenous malformations (BAVM) represent a congenital anomaly of the cerebral vessels with a prevalence...
Link:
https://jmg.bmj.com/content/55/10/675.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang K, Zhao S, Liu B, Zhang Q, Li Y, Liu J, Shen Y, Ding X, Lin J, Wu Y, Yan Z, Chen J, Li X, Song X, Niu Y, Liu J, Chen W, Ming Y, Du R, Chen C, Long B, Zhang Y, Tong X, Zhang S, Posey JE, Zhang B, Wu Z, Wythe JD, Liu P, Lupski JR, Yang X, Wu N. Perturbations of BMP/TGF-β and VEGF/VEGFR signalling pathways in non-syndromic sporadic brain arteriovenous malformations (BAVM). J Med Genet. 2018 Aug 17. pii: jmedgenet-2017-105224. doi: 10.1136/jmedgenet-2017-105224. [Epub ahead of print].

Genome Editing Reveals Idiosyncrasy of CNGA2 Ion Channel-Directed Antibody Immunoreactivity Toward Oxytocin

Authors:
Blechman J, Anbalagan S, Matthews GG, Levkowitz G
Citation:
Front Cell Dev Biol. 2018. doi:10.3389/fcell.2018.00117
Epub:
Not Epub
Abstract:
Presynaptic cGMP-gated ion (CNG) channels positively or negatively modulate neurotransmitter secretion as well as the strength...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2018.00117/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blechman J, Anbalagan S, Matthews GG, Levkowitz G. Genome Editing Reveals Idiosyncrasy of CNGA2 Ion Channel-Directed Antibody Immunoreactivity Toward Oxytocin. Front Cell Dev Biol. 2018. doi:10.3389/fcell.2018.00117.

A transgenic zebrafish model for in vivo long-term imaging of retinotectal synaptogenesis

Authors:
Du X-f, Xu B, Zhang Y, Chen M-j, Du J-l
Citation:
Sci Rep. 2018;8:14077. doi:10.1038/s41598-018-32409-y
Epub:
Not Epub
Abstract:
The retinotectal synapse in larval zebrafish, combined with live time-lapse imaging, provides an advantageous model for study...
Link:
https://www.nature.com/articles/s41598-018-32409-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Du X-f, Xu B, Zhang Y, Chen M-j, Du J-l. A transgenic zebrafish model for in vivo long-term imaging of retinotectal synaptogenesis. Sci Rep. 2018;8:14077. doi:10.1038/s41598-018-32409-y.

CREST in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, and synaptic plasticity

Authors:
Alaghband Y, Kramár E, Kwapis JL, Kim ES, Hemstedt TJ, López AJ, White AO, Al-Kachak A, Aimiuwu OV, Bodinayake KK, Oparaugo NC, Han J, Lattal KM, Wood MA
Citation:
J Neurosci. 2018. doi:10.1523/JNEUROSCI.2911-17.2018
Epub:
Not Epub
Abstract:
Epigenetic mechanisms result in persistent changes at the cellular level that can lead to long-lasting behavioral adaptations....
Link:
http://www.jneurosci.org/content/early/2018/09/18/JNEUROSCI.2911-17.2018
Delivery Method:
nucleus accumbens infusion
Organism or Cell Type:
Rattus (rat)
Citation Extract:
Alaghband Y, Kramár E, Kwapis JL, Kim ES, Hemstedt TJ, López AJ, White AO, Al-Kachak A, Aimiuwu OV, Bodinayake KK, Oparaugo NC, Han J, Lattal KM, Wood MA. CREST in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, and synaptic plasticity. J Neurosci. 2018. doi:10.1523/JNEUROSCI.2911-17.2018.

Stromal interaction molecule 1 is required for neonatal testicular development in mice

Authors:
Shen C, Zhang K, Yu J, Guo Y, Gao T, Liu Y, Zhang X, Chen X, Yu Y, Cheng H, Zheng A, Li H, Huang X, Ding X, Zheng B
Citation:
Biochem Biophys Res Commun. 2018 Sep 14. pii: S0006-291X(18)31962-4. doi: 10.1016/j.bbrc.2018.09.044. [Epub ahead of print]
Epub:
Yes
Abstract:
Stromal interaction molecule 1 (STIM1) is a transmembrane endoplasmic reticulum protein, and it serves as a Ca2+ sensor and...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X18319624?via%3Dihub
Organism or Cell Type:
explant: mouse neonatal testis culture
Citation Extract:
Shen C, Zhang K, Yu J, Guo Y, Gao T, Liu Y, Zhang X, Chen X, Yu Y, Cheng H, Zheng A, Li H, Huang X, Ding X, Zheng B. Stromal interaction molecule 1 is required for neonatal testicular development in mice. Biochem Biophys Res Commun. 2018 Sep 14. pii: S0006-291X(18)31962-4. doi: 10.1016/j.bbrc.2018.09.044. [Epub ahead of print].

Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish

Authors:
Mitra S, Sharma P, Kaur S, Khursheed MA, Gupta S, Ahuja R, Kurup AJ, Chaudhary M, Ramachandran R
Citation:
iScience. 2018;7:68-84. doi:10.1016/j.isci.2018.08.008
Epub:
Not Epub
Abstract:
Histone deacetylases (Hdacs) play significant roles in cellular homeostasis and tissue differentiation. Hdacs are well...
Link:
https://www.sciencedirect.com/science/article/pii/S2589004218301202
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Mitra S, Sharma P, Kaur S, Khursheed MA, Gupta S, Ahuja R, Kurup AJ, Chaudhary M, Ramachandran R. Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish. iScience. 2018;7:68-84. doi:10.1016/j.isci.2018.08.008.

Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance

Authors:
Dong L, Pietsch S, Tan Z, Perner B, Sierig R, Kruspe D, Groth M, Witzgall R, Gröne HJ, Platzer M, Englert C
Citation:
J Am Soc Nephrol. 2015 Sep;26(9):2118-28. doi: 10.1681/ASN.2014080819. Epub 2015 Jan 2
Epub:
Not Epub
Abstract:
The Wilms' tumor suppressor gene 1 (WT1) encodes a zinc finger transcription factor. Mutation of WT1 in humans leads to...
Link:
https://jasn.asnjournals.org/content/early/2015/01/01/ASN.2014080819.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong L, Pietsch S, Tan Z, Perner B, Sierig R, Kruspe D, Groth M, Witzgall R, Gröne HJ, Platzer M, Englert C. Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance. J Am Soc Nephrol. 2015 Sep;26(9):2118-28. doi: 10.1681/ASN.2014080819. Epub 2015 Jan 2.

MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo

Authors:
Molina MD, Quirin M, Haillot E, De Crozé N, Range R, Rouel M, Jimenez F, Amrouche R, Chessel A, Lepage T
Citation:
PLoS Genet. 2018;14(9):e1007621. doi:10.1371/journal.pgen.1007621
Epub:
Not Epub
Abstract:
In the sea urchin embryo, specification of the dorsal-ventral axis critically relies on the spatially restricted expression of...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007621
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Molina MD, Quirin M, Haillot E, De Crozé N, Range R, Rouel M, Jimenez F, Amrouche R, Chessel A, Lepage T. MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo. PLoS Genet. 2018;14(9):e1007621. doi:10.1371/journal.pgen.1007621.

Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury

Authors:
Yao M, Rogers NM, Csányi G, Rodriguez AI, Ross MA, St Croix C, Knupp H, Novelli EM, Thomson AW, Pagano PJ, Isenberg JS
Citation:
J Am Soc Nephrol. 2014 Jun;25(6):1171-86. doi: 10.1681/ASN.2013040433. Epub 2014 Feb 7. Erratum in: J Am Soc Nephrol. 2014 Aug;25(8):1884
Epub:
Not Epub
Abstract:
Ischemia reperfusion injury (IRI) causes tissue and organ injury, in part, through alterations in tissue blood flow and the...
Link:
https://jasn.asnjournals.org/content/early/2014/02/05/ASN.2013040433
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: rat aortic VSMC
Citation Extract:
Yao M, Rogers NM, Csányi G, Rodriguez AI, Ross MA, St Croix C, Knupp H, Novelli EM, Thomson AW, Pagano PJ, Isenberg JS. Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury. J Am Soc Nephrol. 2014 Jun;25(6):1171-86. doi: 10.1681/ASN.2013040433. Epub 2014 Feb 7. Erratum in: J Am Soc Nephrol. 2014 Aug;25(8):1884.

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