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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
CTCF knockout reveals an essential role for this protein during the zebrafish development
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Citation:
Mech Dev. 2018 May 1. pii: S0925-4773(18)30011-X. doi: 10.1016/j.mod.2018.04.006. [Epub ahead of print] Epub:
Yes Abstract:
Chromatin regulation and organization are essential processes that regulate gene activity. The CCCTC-binding factor (CTCF) is a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Carmona-Aldana F, Zampedri C, Suaste-Olmos F, Murillo-de-Ozores A, Guerrero G, Arzate-Mejía R, Maldonado E, Navarro R, Chimal-Monroy J, Recillas-Targa F. CTCF knockout reveals an essential role for this protein during the zebrafish development. Mech Dev. 2018 May 1. pii: S0925-4773(18)30011-X. doi: 10.1016/j.mod.2018.04.006. [Epub ahead of print]. |
Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers
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Citation:
JCI Insight. 2018 May 3;3(9). pii: 99357. doi: 10.1172/jci.insight.99357. [Epub ahead of print] Epub:
Not Epub Abstract:
Exon skipping uses chemically modified antisense oligonucleotides to modulate RNA splicing. Therapeutically, exon skipping can... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: human primary fibroblasts differentiated to myogenic cells Citation Extract: Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM. Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers. JCI Insight. 2018 May 3;3(9). pii: 99357. doi: 10.1172/jci.insight.99357. [Epub ahead of print]. |
The Role of Palladin in Podocytes
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Citation:
J Am Soc Nephrol. 2018 May 2. pii: ASN.2017091039. doi: 10.1681/ASN.2017091039. [Epub ahead of print] Epub:
Yes Abstract:
Background: Podocyte loss and effacement of interdigitating podocyte foot processes are the major cause of a leaky filtration... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Artelt N, Ludwig TA, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, van den Brandt J, Otey CA, Bang ML, Amann K, Chadjichristos CE, Chatziantoniou C, Endlich K, Endlich N. The Role of Palladin in Podocytes. J Am Soc Nephrol. 2018 May 2. pii: ASN.2017091039. doi: 10.1681/ASN.2017091039. [Epub ahead of print]. |
let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration
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Citation:
Cell Rep. 2018;23(5):1409-23. doi:10.1016/j.celrep.2018.04.002 Epub:
Not Epub Abstract:
Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics... Delivery Method:
injection and electroporation Organism or Cell Type:
zebrafish Citation Extract: Kaur S, Gupta S, Chaudhary M, Khursheed MA, Mitra S, Kurup AJ, Ramachandran R. let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration. Cell Rep. 2018;23(5):1409-23. doi:10.1016/j.celrep.2018.04.002. |
Control of Pem protein level by localized maternal factors for transcriptional regulation in the germline of the ascidian, Halocynthia roretzi
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Citation:
PLoS ONE. 2018;13(4):e0196500. doi:10.1371/journal.pone.0196500 Epub:
Not Epub Abstract:
Localized maternal mRNAs play important roles in embryogenesis, e.g. the establishment of embryonic axes and the developmental... Delivery Method:
microinjection Organism or Cell Type:
Halocynthia roretzi Citation Extract: Miyaoku K, Nakamoto A, Nishida H, Kumano G. Control of Pem protein level by localized maternal factors for transcriptional regulation in the germline of the ascidian, Halocynthia roretzi. PLoS ONE. 2018;13(4):e0196500. doi:10.1371/journal.pone.0196500. |
The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum
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Citation:
Dev Biol. 2018;[Epub] doi:10.1016/j.ydbio.2018.04.021 Epub:
Yes Abstract:
Internal organs exhibit left-right asymmetric sizes, shapes and anatomical positions, but how these different lateralities... Organism or Cell Type:
Xenopus Citation Extract: Womble M, Amin NM, Nascone-Yoder N. The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum. Dev Biol. 2018;[Epub] doi:10.1016/j.ydbio.2018.04.021. |
Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm
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Citation:
Cancer Cell Microenviron. 2018;5(1). pii: e1630. doi: 10.14800/ccm.1630. Epub 2018 Apr 9 Epub:
Not Epub Abstract:
Specialized renal epithelial cells known as podocytes are essential components of the filtering structures within the kidney... Citation Extract: Drummond BE, Wingert RA. Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm. Cancer Cell Microenviron. 2018;5(1). pii: e1630. doi: 10.14800/ccm.1630. Epub 2018 Apr 9. |
Functional enrichment analysis based on long noncoding RNA associations
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Citation:
BMC Sys Biol. 2018;12(Suppl 4):45. doi:10.1186/s12918-018-0571-0 Epub:
Not Epub Abstract:
Background: Differential gene expression analysis using RNA-seq data is a popular approach for discovering specific regulation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hung K-S, Hsiao C-C, Pai T-W, Hu C-H, Tzou W-S, Wang W-D, Chen Y-R. Functional enrichment analysis based on long noncoding RNA associations. BMC Sys Biol. 2018;12(Suppl 4):45. doi:10.1186/s12918-018-0571-0. |
Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
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Citation:
Nat Commun. 2018 Apr 24;9(1):1636. doi: 10.1038/s41467-018-04100-3 Epub:
Not Epub Abstract:
Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for... Delivery Method:
Hiperfect (Qiagen) Organism or Cell Type:
cell culture: MCF-7 Citation Extract: Ntini E, Louloupi A, Liz J, Muino JM, Marsico A, Ørom UAV. Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin. Nat Commun. 2018 Apr 24;9(1):1636. doi: 10.1038/s41467-018-04100-3. |
Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae
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Citation:
Front Endocrinol. 2018;[Epub] doi:10.3389/fendo.2018.00230 Epub:
Yes Abstract:
Teleost fish are known to express two isoforms of P450aromatase, a key enzyme for estrogen synthesis. One of the isoforms,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ulhaq ZS, Kishida M. Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae. Front Endocrinol. 2018;[Epub] doi:10.3389/fendo.2018.00230. |