You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Heart enhancers with deeply conserved regulatory activity are established early in development

Authors:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD
Citation:
Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z
Epub:
Not Epub
Abstract:
During the phylotypic period, embryos from different genera show similar gene expression patterns, implying common regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD. Heart enhancers with deeply conserved regulatory activity are established early in development. Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z.

Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish

Authors:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S
Citation:
Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May
Epub:
Not Epub
Abstract:
Objective: DEPDC5 was identified as a major genetic cause of focal epilepsy with deleterious mutations found in a wide range of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S. Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish. Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May.

Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish

Authors:
Berrun A, Harris E, Stachura DL
Citation:
PLoS One. 2018 May 14;13(5):e0196872. doi: 10.1371/journal.pone.0196872. eCollection 2018
Epub:
Not Epub
Abstract:
Hematopoiesis is an essential and highly regulated biological process that begins with hematopoietic stem cells (HSCs). In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berrun A, Harris E, Stachura DL. Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish. PLoS One. 2018 May 14;13(5):e0196872. doi: 10.1371/journal.pone.0196872. eCollection 2018.

Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish

Authors:
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran MC, Sittaramane V, Chandrasekhar A
Citation:
Mech Dev. 2018 May 16. pii: S0925-4773(18)30082-0. doi: 10.1016/j.mod.2018.05.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Contactin2 (Cntn2)/Transient Axonal Glycoprotein 1 (Tag1), a neural cell adhesion molecule, has established roles in neuronal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gurung S, Asante E, Hummel D, Williams A, Feldman-Schultz O, Halloran MC, Sittaramane V, Chandrasekhar A. Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish. Mech Dev. 2018 May 16. pii: S0925-4773(18)30082-0. doi: 10.1016/j.mod.2018.05.005. [Epub ahead of print].

GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer

Authors:
Checa-Rojas A, Delgadillo-Silva LF, Velasco-Herrera MDC, Andrade-Domínguez A, Gil J, Santillán O, Lozano L, Toledo-Leyva A, Ramírez-Torres A, Talamas-Rohana P, Encarnación-Guevara S
Citation:
Oncotarget. 2018 Apr 24;9(31):21696-21714. doi: 10.18632/oncotarget.24796. eCollection 2018 Apr 24
Epub:
Not Epub
Abstract:
The molecular processes and proteomic markers leading to tumor progression (TP) in cervical cancer (CC) are either unknown or...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: HeLa, HaCaT, SiHA, CC; murine xenograft: SiHa, CaSki, HeLa, CaLo, MDA, CoLo
Citation Extract:
Checa-Rojas A, Delgadillo-Silva LF, Velasco-Herrera MDC, Andrade-Domínguez A, Gil J, Santillán O, Lozano L, Toledo-Leyva A, Ramírez-Torres A, Talamas-Rohana P, Encarnación-Guevara S. GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer. Oncotarget. 2018 Apr 24;9(31):21696-21714. doi: 10.18632/oncotarget.24796. eCollection 2018 Apr 24.

Small GTPase R-Ras participates in neural tube formation in zebrafish embryonic spinal cord

Authors:
Ohata S, Uga H, Okamoto H, Katada T
Citation:
Biochem Biophys Res Commun. 2018 May 14. pii: S0006-291X(18)31131-8. doi: 10.1016/j.bbrc.2018.05.074. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ras related (R-Ras), a small GTPase, is involved in the maintenance of apico-basal polarity in neuroepithelial cells of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ohata S, Uga H, Okamoto H, Katada T. Small GTPase R-Ras participates in neural tube formation in zebrafish embryonic spinal cord. Biochem Biophys Res Commun. 2018 May 14. pii: S0006-291X(18)31131-8. doi: 10.1016/j.bbrc.2018.05.074. [Epub ahead of print].

The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity

Authors:
Zhu J, Huang X, Jiang H, Hu L, Michal JJ, Jiang Z, Shi H
Citation:
Sci Total Environ. 2018 Aug 15;633:1245-1252. doi: 10.1016/j.scitotenv.2018.03.313. Epub 2018 Mar 30
Epub:
Not Epub
Abstract:
Evidence has shown that triphenyltin (TPT) triggers severe malformations in Xenopus tropicalis embryos, partly due to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Zhu J, Huang X, Jiang H, Hu L, Michal JJ, Jiang Z, Shi H. The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity. Sci Total Environ. 2018 Aug 15;633:1245-1252. doi: 10.1016/j.scitotenv.2018.03.313. Epub 2018 Mar 30.

Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts

Authors:
Lee J, Echigoya Y, Duddy W, Saito T, Aoki Y, Takeda S, Yokota T
Citation:
PLoS One. 2018 May 17;13(5):e0197084. doi: 10.1371/journal.pone.0197084. eCollection 2018
Epub:
Not Epub
Abstract:
Antisense-mediated exon skipping has made significant progress as a therapeutic platform in recent years, especially in the...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary figroblasts differentiated to myotubes
Citation Extract:
Lee J, Echigoya Y, Duddy W, Saito T, Aoki Y, Takeda S, Yokota T. Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts. PLoS One. 2018 May 17;13(5):e0197084. doi: 10.1371/journal.pone.0197084. eCollection 2018.

Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis

Authors:
Boopathy GTK, Kulkarni M, Ho SY, Boey A, Chua EWM, Barathi VA, Carney TJ, Wang X, Hong W
Citation:
J Biol Chem. 2017 Oct 27;292(43):17760-17776. doi: 10.1074/jbc.M117.794743. Epub 2017 Sep 14
Epub:
Not Epub
Abstract:
Angiogenesis is a highly regulated process for formation of new blood vessels from pre-existing ones. Angiogenesis is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boopathy GTK, Kulkarni M, Ho SY, Boey A, Chua EWM, Barathi VA, Carney TJ, Wang X, Hong W. Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis. J Biol Chem. 2017 Oct 27;292(43):17760-17776. doi: 10.1074/jbc.M117.794743. Epub 2017 Sep 14.

Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1

Authors:
Dery KJ, Silver C, Yang L, Shively JE
Citation:
J Biol Chem. 2018 May 2. pii: jbc.RA117.001507. doi: 10.1074/jbc.RA117.001507. [Epub ahead of print]
Epub:
Yes
Abstract:
The adhesion protein Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is widely expressed in epithelial...
Organism or Cell Type:
cell culture: MDA-MB-468(breast cancer)
Citation Extract:
Dery KJ, Silver C, Yang L, Shively JE. Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1. J Biol Chem. 2018 May 2. pii: jbc.RA117.001507. doi: 10.1074/jbc.RA117.001507. [Epub ahead of print].

Pages