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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish

Authors:
Lai JKH, Collins MM, Uribe V, Jiménez-Amilburu V, Günther S, Maischein HM, Stainier DYR
Citation:
Development. 2018 May 17;145(10). pii: dev159210. doi: 10.1242/dev.159210
Epub:
Not Epub
Abstract:
Cardiac trabeculation is a highly regulated process that starts with the delamination of compact layer cardiomyocytes. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lai JKH, Collins MM, Uribe V, Jiménez-Amilburu V, Günther S, Maischein HM, Stainier DYR. The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Development. 2018 May 17;145(10). pii: dev159210. doi: 10.1242/dev.159210.

Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish

Authors:
Yang Q, Yan C, Gong Z
Citation:
Sci Rep. 2018;8:8495 doi:10.1038/s41598-018-26612-0
Epub:
Not Epub
Abstract:
Activation of hepatic stellate cells (HSC) plays a crucial role in the liver disease progression from liver fibrosis/cirrhosis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Q, Yan C, Gong Z. Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish. Sci Rep. 2018;8:8495 doi:10.1038/s41598-018-26612-0.

A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease

Authors:
Sun CY, Wu MS, Lee CC, Chen SH, Lo KC, Chen YH
Citation:
Sci Rep. 2018 May 24;8(1):8085. doi:10.1038/s41598-018-26460-y
Epub:
Not Epub
Abstract:
We aimed to analyze the associations of single nucleotide polymorphisms (SNP) in the 5' regulatory region of the human...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun CY, Wu MS, Lee CC, Chen SH, Lo KC, Chen YH. A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease. Sci Rep. 2018 May 24;8(1):8085. doi:10.1038/s41598-018-26460-y.

Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Shaky Mouse Model of Startle Disease

Authors:
Schaefer N, Zheng F, van Brederode J, Berger A, Leacock S, Hirata H, Paige CJ, Harvey RJ, Alzheimer C, Villmann C
Citation:
Front Mol Neurosci. 2018:[Epub]doi:10.3389/fnmol.2018.00167
Epub:
Yes
Abstract:
Mutations in GlyR α1 or β subunit genes in humans and rodents lead to severe startle disease characterized by rigidity, massive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schaefer N, Zheng F, van Brederode J, Berger A, Leacock S, Hirata H, Paige CJ, Harvey RJ, Alzheimer C, Villmann C. Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Shaky Mouse Model of Startle Disease. Front Mol Neurosci. 2018:[Epub]doi:10.3389/fnmol.2018.00167.

Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects

Authors:
Liu C, Cao R, Xu Y, Li T, Li F, Chen S, Xu R, Sun K
Citation:
Genome Med. 2018 May 30;10(1):40. doi: 10.1186/s13073-018-0549-y
Epub:
Not Epub
Abstract:
BACKGROUND: Heterotaxy (Htx) syndrome comprises a class of congenital disorders resulting from malformations in left-right body...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu C, Cao R, Xu Y, Li T, Li F, Chen S, Xu R, Sun K. Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects. Genome Med. 2018 May 30;10(1):40. doi: 10.1186/s13073-018-0549-y.

Continuous addition of progenitors forms the cardiac ventricle in zebrafish

Authors:
Felker A, Prummel KD, Merks AM, Mickoleit M, Brombacher EC, Huisken J, Panáková D, Mosimann C
Citation:
Nat Commun. 2018 May 21;9(1):2001. doi: 10.1038/s41467-018-04402-6
Epub:
Not Epub
Abstract:
The vertebrate heart develops from several progenitor lineages. After early-differentiating first heart field (FHF) progenitors...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Felker A, Prummel KD, Merks AM, Mickoleit M, Brombacher EC, Huisken J, Panáková D, Mosimann C. Continuous addition of progenitors forms the cardiac ventricle in zebrafish. Nat Commun. 2018 May 21;9(1):2001. doi: 10.1038/s41467-018-04402-6.

Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation

Authors:
DuBuc TQ, Stephenson TB, Rock AQ, Martindale MQ
Citation:
Nat Commun. 2018 May 22;9(1):2007. doi: 10.1038/s41467-018-04184-x
Epub:
Not Epub
Abstract:
Hox gene transcription factors are important regulators of positional identity along the anterior-posterior axis in bilaterian...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
DuBuc TQ, Stephenson TB, Rock AQ, Martindale MQ. Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation. Nat Commun. 2018 May 22;9(1):2007. doi: 10.1038/s41467-018-04184-x.

miR-133 mediated regulation of the hedgehog pathway orchestrates embryo myogenesis

Authors:
Mok GF, Lozano-Velasco E, Maniou E, Viaut C, Moxon S, Wheeler G, Münsterberg A
Citation:
Development. 2018 May 25. pii: dev.159657. doi: 10.1242/dev.159657. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal myogenesis serves as a paradigm to investigate the molecular mechanisms underlying exquisitely regulated cell fate...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Mok GF, Lozano-Velasco E, Maniou E, Viaut C, Moxon S, Wheeler G, Münsterberg A. miR-133 mediated regulation of the hedgehog pathway orchestrates embryo myogenesis. Development. 2018 May 25. pii: dev.159657. doi: 10.1242/dev.159657. [Epub ahead of print].

Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals

Authors:
Gentsch GE, Spruce T, Owens NDL, Smith JC
Citation:
BioRxiv. 2018. doi:10.1101/306803
Epub:
Not Epub
Abstract:
The ability of cells to respond to intercellular signals, and the repertoire of possible responses to those signals, is defined...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals. BioRxiv. 2018. doi:10.1101/306803 .

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish

Authors:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN
Citation:
bioRxiv. 2018. doi:10.1101/308221
Epub:
Not Epub
Abstract:
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN. Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish. bioRxiv. 2018. doi:10.1101/308221.

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