You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

A SLC4 family bicarbonate transporter is critical for intracellular pH regulation and biomineralization in sea urchin embryos

Authors:
Hu MY, Yan JJ, Petersen I, Himmerkus N, Bleich M, Stumpp M
Citation:
Elife. 2018 May 1;7. pii: e36600. doi: 10.7554/eLife.36600. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Efficient pH regulation is a fundamental requisite of all calcifying systems in animals and plants but with the underlying pH...
Link:
https://elifesciences.org/articles/36600
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Hu MY, Yan JJ, Petersen I, Himmerkus N, Bleich M, Stumpp M. A SLC4 family bicarbonate transporter is critical for intracellular pH regulation and biomineralization in sea urchin embryos. Elife. 2018 May 1;7. pii: e36600. doi: 10.7554/eLife.36600. [Epub ahead of print].

ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression

Authors:
Davis JA, Koenig AL, Lubert A, Chestnut B, Liu F, Desai SP, Winkler T, Pociute K, Choi K, Sumanas S
Citation:
Dev Biol. 2018 May 9. pii: S0012-1606(17)30833-3. doi: 10.1016/j.ydbio.2018.05.003. [Epub ahead of print]
Epub:
Yes
Abstract:
The molecular mechanisms initiating the formation of the lymphatic system, lymphangiogenesis, are still poorly understood. Here...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617308333
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davis JA, Koenig AL, Lubert A, Chestnut B, Liu F, Desai SP, Winkler T, Pociute K, Choi K, Sumanas S. ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression. Dev Biol. 2018 May 9. pii: S0012-1606(17)30833-3. doi: 10.1016/j.ydbio.2018.05.003. [Epub ahead of print].

Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production

Authors:
Charleston JS, Schnell FJ, Dworzak J, Donoghue C, Lewis S, Chen L, Young GD, Milici AJ, Voss J, DeAlwis U, Wentworth B, Rodino-Klapac LR, Sahenk Z, Frank D, Mendell JR
Citation:
Neurology. 2018 May 11. pii: 10.1212/WNL.0000000000005680. doi: 10.1212/WNL.0000000000005680. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: To describe the quantification of novel dystrophin production in patients with Duchenne muscular dystrophy (DMD)...
Link:
http://n.neurology.org/content/early/2018/05/11/WNL.0000000000005680.long
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Charleston JS, Schnell FJ, Dworzak J, Donoghue C, Lewis S, Chen L, Young GD, Milici AJ, Voss J, DeAlwis U, Wentworth B, Rodino-Klapac LR, Sahenk Z, Frank D, Mendell JR. Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production. Neurology. 2018 May 11. pii: 10.1212/WNL.0000000000005680. doi: 10.1212/WNL.0000000000005680. [Epub ahead of print].

Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain

Authors:
Addison M, Xu Q, Cayuso J, Wilkinson DG
Citation:
Dev Cell. 2018 Apr 30. pii: S1534-5807(18)30278-8. doi: 10.1016/j.devcel.2018.04.003. [Epub ahead of print]
Epub:
Yes
Abstract:
The patterning of tissues to form subdivisions with distinct and homogeneous regional identity is potentially disrupted by cell...
Link:
https://www.sciencedirect.com/science/article/pii/S1534580718302788
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Addison M, Xu Q, Cayuso J, Wilkinson DG. Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain. Dev Cell. 2018 Apr 30. pii: S1534-5807(18)30278-8. doi: 10.1016/j.devcel.2018.04.003. [Epub ahead of print].

A noncanonical function of histidyl-tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development

Authors:
Ni R, Luo L
Citation:
FEBS Open Bio. 2018 Apr 17;8(5):722-731. doi: 10.1002/2211-5463.12420. eCollection 2018 May
Epub:
Not Epub
Abstract:
Histidyl-tRNA synthetase (Hars) catalyzes the ligation of histidine residues to cognate tRNA. Here, we demonstrate a...
Link:
https://febs.onlinelibrary.wiley.com/doi/abs/10.1002/2211-5463.12420
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ni R, Luo L. A noncanonical function of histidyl-tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development. FEBS Open Bio. 2018 Apr 17;8(5):722-731. doi: 10.1002/2211-5463.12420. eCollection 2018 May.

Cellular nucleic acid-binding protein is vital to testis development and spermatogenesis in mice

Authors:
Zheng B, Gao T, Yu J, Guo Y, Shen C, Zhang X, Li H, Huang X
Citation:
Reproduction. 2018 May 9. pii: REP-17-0666. doi: 10.1530/REP-17-0666. [Epub ahead of print]
Epub:
Yes
Abstract:
The cellular nucleic acid-binding protein (CNBP), also known as zinc finger protein 9 (ZNF9), is a highly conserved zinc finger...
Link:
http://www.reproduction-online.org/content/early/2018/05/09/REP-17-0666.abstract
Organism or Cell Type:
explant: mouse neonatal testis culture
Citation Extract:
Zheng B, Gao T, Yu J, Guo Y, Shen C, Zhang X, Li H, Huang X. Cellular nucleic acid-binding protein is vital to testis development and spermatogenesis in mice. Reproduction. 2018 May 9. pii: REP-17-0666. doi: 10.1530/REP-17-0666. [Epub ahead of print].

Estrogenic mechanisms and cardiac responses following early life exposure to Bisphenol A (BPA) and its metabolite 4-methyl-2,4-bis(p-hydroxyphenyl)pent-1-ene (MBP) in zebrafish

Authors:
Moreman J, Takesono A, Trznadel M, Winter M, Perry A, Wood M, Rogers NJ, Kudoh T, Tyler CR
Citation:
Environ Sci Technol. 2018 May 8. doi: 10.1021/acs.est.8b01095. [Epub ahead of print]
Epub:
Yes
Abstract:
Environmental exposure to Bisphenol A (BPA) has been associated with a range of adverse health effects, including on the...
Link:
https://pubs.acs.org/doi/10.1021/acs.est.8b01095
Organism or Cell Type:
zebrafish
Citation Extract:
Moreman J, Takesono A, Trznadel M, Winter M, Perry A, Wood M, Rogers NJ, Kudoh T, Tyler CR. Estrogenic mechanisms and cardiac responses following early life exposure to Bisphenol A (BPA) and its metabolite 4-methyl-2,4-bis(p-hydroxyphenyl)pent-1-ene (MBP) in zebrafish. Environ Sci Technol. 2018 May 8. doi: 10.1021/acs.est.8b01095. [Epub ahead of print].

Live imaging reveals a conserved role of fatty acid β-oxidation in early lymphatic development in zebrafish

Authors:
Zecchin A, Wong B, Tembuyser B, Souffreau J, Van Nuffelen A, Wyns S, Vinckier S, Carmeliet P, Dewerchin M
Citation:
Biochem Biophys Res Commun. 2018 May 3. pii: S0006-291X(18)31037-4. doi: 10.1016/j.bbrc.2018.04.233. [Epub ahead of print]
Epub:
Yes
Abstract:
During embryonic development, lymphatic endothelial cells (LECs) differentiate from venous endothelial cells (VECs), a process...
Link:
https://www.ncbi.nlm.nih.gov/pubmed/29730294
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zecchin A, Wong B, Tembuyser B, Souffreau J, Van Nuffelen A, Wyns S, Vinckier S, Carmeliet P, Dewerchin M. Live imaging reveals a conserved role of fatty acid β-oxidation in early lymphatic development in zebrafish. Biochem Biophys Res Commun. 2018 May 3. pii: S0006-291X(18)31037-4. doi: 10.1016/j.bbrc.2018.04.233. [Epub ahead of print].

Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy

Authors:
Burns DT, Donkervoort S, Müller JS, Knierim E, Bharucha-Goebel D, Faqeih EA, Bell SK, AlFaifi AY, Monies D, Millan F, Retterer K, Dyack S, MacKay S, Morales-Gonzalez S, Giunta M, Munro B, Hudson G, Scavina M, Baker L, Massini TC, Lek M, Hu Y, Ezzo D, AlKuraya FS, Kang PB, Griffin H, Foley AR, Schuelke M, Horvath R, Bönnemann CG
Citation:
Am J Hum Genet. 2018 May 3;102(5):858-873. doi: 10.1016/j.ajhg.2018.03.011
Epub:
Not Epub
Abstract:
The exosome is a conserved multi-protein complex that is essential for correct RNA processing. Recessive variants in exosome...
Link:
https://www.cell.com/ajhg/fulltext/S0002-9297(18)30100-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burns DT, Donkervoort S, Müller JS, Knierim E, Bharucha-Goebel D, Faqeih EA, Bell SK, AlFaifi AY, Monies D, Millan F, Retterer K, Dyack S, MacKay S, Morales-Gonzalez S, Giunta M, Munro B, Hudson G, Scavina M, Baker L, Massini TC, Lek M, Hu Y, Ezzo D, AlKuraya FS, Kang PB, Griffin H, Foley AR, Schuelke M, Horvath R, Bönnemann CG. Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy. Am J Hum Genet. 2018 May 3;102(5):858-873. doi: 10.1016/j.ajhg.2018.03.011.

Temporal and Spatial Post-Transcriptional Regulation of Zebrafish Tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly

Authors:
Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R
Citation:
Arterioscler Thromb Vasc Biol. 2018 May 3. pii: ATVBAHA.118.310848. doi: 10.1161/ATVBAHA.118.310848. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Tie1 (tyrosine kinase containing immunoglobulin and epidermal growth factor homology 1), an endothelial and...
Link:
http://atvb.ahajournals.org/content/early/2018/05/02/ATVBAHA.118.310848.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R. Temporal and Spatial Post-Transcriptional Regulation of Zebrafish Tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly. Arterioscler Thromb Vasc Biol. 2018 May 3. pii: ATVBAHA.118.310848. doi: 10.1161/ATVBAHA.118.310848. [Epub ahead of print].

Pages