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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Polarity and morphogenesis of the eye epithelium requires the adhesion junction associated adaptor protein Traf4

Authors:
Hehr CL, Halabi R, McFarlane S
Citation:
Cell Adh Migr. 2018 Jul 31:1-14. doi: 10.1080/19336918.2018.1477900. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During development, neuroepithelial progenitors acquire apico-basal polarity and adhere to one another via apically located...
Organism or Cell Type:
zebrafish
Citation Extract:
Hehr CL, Halabi R, McFarlane S. Polarity and morphogenesis of the eye epithelium requires the adhesion junction associated adaptor protein Traf4. Cell Adh Migr. 2018 Jul 31:1-14. doi: 10.1080/19336918.2018.1477900. [Epub ahead of print].

Alternative splicing of (ppp1r12a/mypt1) in zebrafish produces a novel myosin phosphatase targeting subunit

Authors:
LaFlamme A, Young KE, Lang I, Weiser DC
Citation:
Gene. 2018 Jun 27. pii: S0378-1119(18)30753-4. doi: 10.1016/j.gene.2018.06.092. [Epub ahead of print]
Epub:
Yes
Abstract:
Myosin phosphatase is an evolutionarily conserved regulator of actomyosin contractility, comprised of a regulatory subunit (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
LaFlamme A, Young KE, Lang I, Weiser DC. Alternative splicing of (ppp1r12a/mypt1) in zebrafish produces a novel myosin phosphatase targeting subunit. Gene. 2018 Jun 27. pii: S0378-1119(18)30753-4. doi: 10.1016/j.gene.2018.06.092. [Epub ahead of print].

Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function

Authors:
Chitramuthu BP, Bennett HPJ
Citation:
Methods Mol Biol. 2018;1806:207-231. doi: 10.1007/978-1-4939-8559-3_15
Epub:
Not Epub
Abstract:
The zebrafish (Danio rerio), a small tropical fish, has become a powerful model for the study of early vertebrate development,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chitramuthu BP, Bennett HPJ. Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function. Methods Mol Biol. 2018;1806:207-231. doi: 10.1007/978-1-4939-8559-3_15.

Effect of Tim23 Knockdown in vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPRmt in Muscle

Authors:
Oliveira AN, Hood DA
Citation:
Am J Physiol Cell Physiol. 2018 Jun 27. doi: 10.1152/ajpcell.00275.2017. [Epub ahead of print]
Epub:
Yes
Abstract:
The mitochondrial unfolded protein response (UPRmt) is a protein quality control mechanism that strives to achieve proteostasis...
Delivery Method:
Vivo-Morpholino
Citation Extract:
Oliveira AN, Hood DA. Effect of Tim23 Knockdown in vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPRmt in Muscle. Am J Physiol Cell Physiol. 2018 Jun 27. doi: 10.1152/ajpcell.00275.2017. [Epub ahead of print].

Cxcl12a induces snail1b expression to initiate collective migration and sequential Fgf-dependent neuromast formation in the zebrafish posterior lateral line primordium

Authors:
Neelathi UM, Dalle Nogare D, Chitnis AB
Citation:
Development. 2018 Jul 30;145(14). pii: dev162453. doi: 10.1242/dev.162453
Epub:
Not Epub
Abstract:
The zebrafish posterior lateral line primordium migrates along a path defined by the chemokine Cxcl12a, periodically depositing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Neelathi UM, Dalle Nogare D, Chitnis AB. Cxcl12a induces snail1b expression to initiate collective migration and sequential Fgf-dependent neuromast formation in the zebrafish posterior lateral line primordium. Development. 2018 Jul 30;145(14). pii: dev162453. doi: 10.1242/dev.162453.

FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy

Authors:
McMillin M, Grant S, Frampton G, Petrescu AD, Kain J, Williams E, Haines R, Canady L, DeMorrow S
Citation:
Cell Mol Gastroenterol Hepatol. 2018 Mar 6;6(1):47-63. doi: 10.1016/j.jcmgh.2018.02.008. eCollection 2018
Epub:
Not Epub
Abstract:
Background & Aims: Hepatic encephalopathy is a serious neurologic complication of acute and chronic liver diseases. We...
Delivery Method:
Vivo-Morpholino & Endo-Porter, Alzet pump
Organism or Cell Type:
C57Bl/6 mice
Citation Extract:
McMillin M, Grant S, Frampton G, Petrescu AD, Kain J, Williams E, Haines R, Canady L, DeMorrow S. FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy. Cell Mol Gastroenterol Hepatol. 2018 Mar 6;6(1):47-63. doi: 10.1016/j.jcmgh.2018.02.008. eCollection 2018.

Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression

Authors:
Moreno RL, Williams K, Jones KL, Ribera AB
Citation:
PLoS One. 2018 Jun 21;13(6):e0199233. doi: 10.1371/journal.pone.0199233. eCollection 2018
Epub:
Not Epub
Abstract:
Zebrafish primary motor neurons differ from each other with respect to morphology, muscle targets and electrophysiological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moreno RL, Williams K, Jones KL, Ribera AB. Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression. PLoS One. 2018 Jun 21;13(6):e0199233. doi: 10.1371/journal.pone.0199233. eCollection 2018.

Synthesis, Characterization, and Function of an RNA-Based Transfection Reagent

Authors:
Jain HV, Boehler JF, Nagaraju K, Beaucage SL
Citation:
Curr Protoc Nucleic Acid Chem. 2018 Mar;72(1):4.81.1-4.81.29. doi: 10.1002/cpnc.51
Epub:
Not Epub
Abstract:
A synthetic 8-mer, amphipathic, trans-acting poly-2'-O-methyluridylic thiophosphate triester RNA element (2'-OMeUtaPS...
Delivery Method:
2'-O-Me-PS-RNA carrier
Organism or Cell Type:
cell culture: HeLa pLuc 705, mice mdx
Citation Extract:
Jain HV, Boehler JF, Nagaraju K, Beaucage SL. Synthesis, Characterization, and Function of an RNA-Based Transfection Reagent. Curr Protoc Nucleic Acid Chem. 2018 Mar;72(1):4.81.1-4.81.29. doi: 10.1002/cpnc.51.

Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach

Authors:
Pinto RA, Almeida-Santos J, Lourenço R, Saúde L
Citation:
BMC Dev Biol. 2018 Jun 19;18(1):14. doi: 10.1186/s12861-018-0173-5
Epub:
Not Epub
Abstract:
BACKGROUND: Dmrt2a is a zinc finger like transcription factor with several roles during zebrafish early development: left-right...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pinto RA, Almeida-Santos J, Lourenço R, Saúde L. Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach. BMC Dev Biol. 2018 Jun 19;18(1):14. doi: 10.1186/s12861-018-0173-5.

Assessing the role of the acid-sensing ion channel ASIC4b in sodium uptake by larval zebrafish

Authors:
Zimmer AM, Dymowska AK, Kumai Y, Goss GG, Perry SF, Kwong RWM
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2018 Jun 15;226:1-10. doi: 10.1016/j.cbpa.2018.06.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Na+ uptake in larval zebrafish (Danio rerio) is coordinated by three mechanisms: Na+/H+-exchanger 3b (NHE3b) expressed in H+-...
Organism or Cell Type:
zebrafish
Citation Extract:
Zimmer AM, Dymowska AK, Kumai Y, Goss GG, Perry SF, Kwong RWM. Assessing the role of the acid-sensing ion channel ASIC4b in sodium uptake by larval zebrafish. Comp Biochem Physiol A Mol Integr Physiol. 2018 Jun 15;226:1-10. doi: 10.1016/j.cbpa.2018.06.012. [Epub ahead of print].

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