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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity
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Citation:
eLife. 2018;7:e31018. doi:10.7554/eLife.31018 Epub:
Not Epub Abstract:
The mesodermal germ layer is patterned into mediolateral subtypes by signaling factors including BMP and FGF. How these... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Row RH, Pegg A, Kinney B, Farr GH, Maves L, Lowell S, Wilson V, Martin BL. BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity. eLife. 2018;7:e31018. doi:10.7554/eLife.31018. |
Blocking the 5′ splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch
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Citation:
Sci Rep. 2018;8:8739 doi:10.1038/s41598-018-27104-x Epub:
Not Epub Abstract:
APOL1 risk alleles G1 or G2 are associated with a kidney disease phenotype exclusively in people of recent African ancestry.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: AB8/13 podocytes Citation Extract: Cheatham AM, Davis SE, Khatua AK, Popik W. Blocking the 5′ splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch. Sci Rep. 2018;8:8739 doi:10.1038/s41598-018-27104-x. |
Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy
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Citation:
Sci Transl Med. 2018;10(444):eaat0195. doi:10.1126/scitranslmed.aat0195 Epub:
Not Epub Abstract:
Exosomes are circulating nanovesicular carriers of macromolecules, increasingly used for diagnostics and therapeutics. The... Delivery Method:
exosome Organism or Cell Type:
mice Citation Extract: Gao X, Ran N, Dong X, Zuo B, Yang R, Zhuo Q, Hong M. Moulton HM, Seow Y, Yin HF. Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy. Sci Transl Med. 2018;10(444):eaat0195. doi:10.1126/scitranslmed.aat0195. |
Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors
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Citation:
eLife. 2018;7:e33574. doi:10.7554/eLife.33574 Epub:
Not Epub Abstract:
Chemokines are secreted proteins that regulate a range of processes in eukaryotic organisms. Interestingly, different chemokine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Malhotra D, Shin J, Solnica-Krezel L, Raz E. Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors. eLife. 2018;7:e33574. doi:10.7554/eLife.33574. |
Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish
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Citation:
Mech Dev. 2018;[Epub ahead of print] doi:10.1016/j.mod.2018.06.001 Epub:
Yes Abstract:
Somites sequentially form with a regular interval by the segmentation from the anterior region of the presomitic mesoderm (PSM... Organism or Cell Type:
zebrafish Citation Extract: Kinoshita H, Ohgane N, Fujino Y, Yabe T, Hiroki Ovara H, Yokota D, Izuka A, Kage D, Yamasu K, Takada S, Kawamura A. Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish. Mech Dev. 2018;[Epub ahead of print] doi:10.1016/j.mod.2018.06.001. |
PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis
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Citation:
eLife. 2018;7:e33800 doi: 10.7554/eLife.33800 Epub:
Not Epub Abstract:
Alveolar rhabdomyosarcoma is a pediatric soft-tissue sarcoma caused by PAX3/7-FOXO1 fusion oncogenes and is characterized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. eLife. 2018;7:e33800 doi: 10.7554/eLife.33800. |
The homeobox protein VentX reverts immune suppression in the tumor microenvironment
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Citation:
Nat Comm. 2018;9:2175. doi:10.1038/s41467-018-04567-0 Epub:
Not Epub Abstract:
Immune suppression in the tumor microenvironment (TME) is a central obstacle to effective immunotherapy. Tumor-associated... Delivery Method:
electroporation Organism or Cell Type:
cell culture: human tumor associated macrophages (TAM) or human primary monocytes Citation Extract: Le Y, Gao H, Bleday R, Zhu Z. The homeobox protein VentX reverts immune suppression in the tumor microenvironment. Nat Comm. 2018;9:2175. doi:10.1038/s41467-018-04567-0. |
The macrophage as a Trojan horse for antisense oligonucleotide delivery
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Citation:
Expert Opin Ther Targets. 2018 Jun 4. doi: 10.1080/14728222.2018.1482279. [Epub ahead of print] Epub:
Yes Abstract:
The gateway to the promised land of gene therapy has been obstructed by the problem of accurate and efficient delivery of... Citation Extract: Novak JS, Jaiswal JK, Partridge TA. The macrophage as a Trojan horse for antisense oligonucleotide delivery. Expert Opin Ther Targets. 2018 Jun 4. doi: 10.1080/14728222.2018.1482279. [Epub ahead of print]. |
Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
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Citation:
Nat Comm. 2018;9:2161. doi:10.1038/s41467-018-04566-1 Epub:
Not Epub Abstract:
Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Merks AM, Swinarski M, Meyer AM, Müller NV, Özcan I, Donat S, Burger A, Gilbert S, Mosimann C, Abdelilah-Seyfried S, Panáková D. Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity. Nat Comm. 2018;9:2161. doi:10.1038/s41467-018-04566-1. |
TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons
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Citation:
Dev Biol. 2018 Jun 1;438(1):57-68. doi: 10.1016/j.ydbio.2018.02.011. Epub 2018 Mar 23 Epub:
Not Epub Abstract:
During the development of the early spinal circuitry in zebrafish, spontaneous Ca2+ transients in the primary motor neurons (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kelu JJ, Webb SE, Galione A, Miller AL. TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons. Dev Biol. 2018 Jun 1;438(1):57-68. doi: 10.1016/j.ydbio.2018.02.011. Epub 2018 Mar 23. |