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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

γ-Tubulin small complex formation is essential for early zebrafish embryogenesis

Authors:
Pouchucq L, Undurraga CA, Fuentes R, Cornejo M, Allende ML, Monasterio O
Citation:
Mech Dev. 2018 Jul 3. pii: S0925-4773(18)30061-3. doi: 10.1016/j.mod.2018.06.006. [Epub ahead of print]
Epub:
Yes
Abstract:
The centrosomal protein γ-tubulin is part of the cytoplasmic γ-tubulin small (γ-TuSCs) and large complexes (γ-TuRCs). Both,...
Organism or Cell Type:
zebrafish
Citation Extract:
Pouchucq L, Undurraga CA, Fuentes R, Cornejo M, Allende ML, Monasterio O. γ-Tubulin small complex formation is essential for early zebrafish embryogenesis. Mech Dev. 2018 Jul 3. pii: S0925-4773(18)30061-3. doi: 10.1016/j.mod.2018.06.006. [Epub ahead of print].

Trypanosomes can initiate nuclear export co-transcriptionally

Authors:
Goos C, Dejung M, Wehman AM, M-Natus E, Schmidt J, Sunter J, Engstler M, Butter F, Kramer S
Citation:
Nucleic Acids Res. 2018 Nov 12. doi: 10.1093/nar/gky1136. [Epub ahead of print]
Epub:
Yes
Abstract:
The nuclear envelope serves as important messenger RNA (mRNA) surveillance system. In yeast and human, several control systems...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: Trypanosoma brucei Lister 427 procyclic cells
Citation Extract:
Goos C, Dejung M, Wehman AM, M-Natus E, Schmidt J, Sunter J, Engstler M, Butter F, Kramer S. Trypanosomes can initiate nuclear export co-transcriptionally. Nucleic Acids Res. 2018 Nov 12. doi: 10.1093/nar/gky1136. [Epub ahead of print].

Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis

Authors:
Zhang X, Jia S, Chen Z, Chong YL, Xie H, Feng D, Wu X, Song DZ, Roy S, Zhao C
Citation:
Nat Genet. 2018 Nov 12. doi: 10.1038/s41588-018-0260-3. [Epub ahead of print]
Epub:
Yes
Abstract:
Straightening of the body axis is a major morphogenetic event that produces the typical head-to-tail shape of the vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang X, Jia S, Chen Z, Chong YL, Xie H, Feng D, Wu X, Song DZ, Roy S, Zhao C. Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis. Nat Genet. 2018 Nov 12. doi: 10.1038/s41588-018-0260-3. [Epub ahead of print].

CDC20B is required for deuterosome-mediated centriole production in multiciliated cells

Authors:
Revinski DR, Zaragosi LE, Boutin C, Ruiz-Garcia S, Deprez M, Thomé V, Rosnet O, Gay AS, Mercey O, Paquet A, Pons N, Ponzio G, Marcet B, Kodjabachian L, Barbry P
Citation:
Nat Commun. 2018 Nov 7;9(1):4668. doi: 10.1038/s41467-018-06768-z
Epub:
Not Epub
Abstract:
Multiciliated cells (MCCs) harbor dozens to hundreds of motile cilia, which generate hydrodynamic forces important in animal...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Revinski DR, Zaragosi LE, Boutin C, Ruiz-Garcia S, Deprez M, Thomé V, Rosnet O, Gay AS, Mercey O, Paquet A, Pons N, Ponzio G, Marcet B, Kodjabachian L, Barbry P. CDC20B is required for deuterosome-mediated centriole production in multiciliated cells. Nat Commun. 2018 Nov 7;9(1):4668. doi: 10.1038/s41467-018-06768-z.

Src-transformed cells hijack mitosis to extrude from the epithelium

Authors:
Anton KA, Kajita M, Narumi R, Fujita Y, Tada M
Citation:
Nat Commun. 2018 Nov 8;9(1):4695. doi: 10.1038/s41467-018-07163-4
Epub:
Not Epub
Abstract:
At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anton KA, Kajita M, Narumi R, Fujita Y, Tada M. Src-transformed cells hijack mitosis to extrude from the epithelium. Nat Commun. 2018 Nov 8;9(1):4695. doi: 10.1038/s41467-018-07163-4.

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration

Authors:
Tsarouchas TM, Wehner D, Cavone L, Munir T, Keatinge M, Lambertus M, Underhill A, Barrett T, Kassapis E, Ogryzko N, Feng Y, van Ham TJ, Becker T, Becker CG
Citation:
Nat Commun. 2018 Nov 7;9(1):4670. doi: 10.1038/s41467-018-07036-w
Epub:
Not Epub
Abstract:
Spinal cord injury leads to a massive response of innate immune cells in non-regenerating mammals, but also in successfully...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsarouchas TM, Wehner D, Cavone L, Munir T, Keatinge M, Lambertus M, Underhill A, Barrett T, Kassapis E, Ogryzko N, Feng Y, van Ham TJ, Becker T, Becker CG. Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration. Nat Commun. 2018 Nov 7;9(1):4670. doi: 10.1038/s41467-018-07036-w.

Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations

Authors:
Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X
Citation:
Sci Adv. 2018 Nov 7;4(11):eaau0731. doi: 10.1126/sciadv.aau0731. eCollection 2018 Nov
Epub:
Not Epub
Abstract:
Cerebral cavernous malformation (CCM) is a common cerebrovascular disease that can occur sporadically or be inherited. They are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X. Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations. Sci Adv. 2018 Nov 7;4(11):eaau0731. doi: 10.1126/sciadv.aau0731. eCollection 2018 Nov.

Growth Cone Tctp Is Dynamically Regulated by Guidance Cues

Authors:
Roque CG, Holt CE
Citation:
Front Mol Neurosci. 2018;[Epub] doi:10.3389/fnmol.2018.00399
Epub:
Not Epub
Abstract:
Translationally controlled tumor protein (Tctp) contributes to retinal circuitry formation by promoting axon growth and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Roque CG, Holt CE. Growth Cone Tctp Is Dynamically Regulated by Guidance Cues. Front Mol Neurosci. 2018;[Epub] doi:10.3389/fnmol.2018.00399.

Basal extrusion drives cell invasion and mechanical stripping of E-cadherin

Authors:
Fadul J, Slattum GM, Redd NM, Zulueta-Coarasa TF, Redd M, Daetwyler S, Hedeen D, Huisken J, Rosenblatt J
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/463646
Epub:
Not Epub
Abstract:
Metastasis is the predominant reason that patients succumb to cancer, yet the mechanisms that drive initial tumor cell invasion...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fadul J, Slattum GM, Redd NM, Zulueta-Coarasa TF, Redd M, Daetwyler S, Hedeen D, Huisken J, Rosenblatt J. Basal extrusion drives cell invasion and mechanical stripping of E-cadherin. bioRxive. 2018;[Preprint] doi:10.1101/463646.

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo

Authors:
Dickinson AJG, Bharathan NK
Citation:
bioRxive. 2018:{preprint] doi:10.1101/464370
Epub:
Not Epub
Abstract:
Desmoplakin (Dsp) is a unique and critical desmosomal protein, however, it is unclear whether this protein and desmosomes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dickinson AJG, Bharathan NK. Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo. bioRxive. 2018:{preprint] doi:10.1101/464370.

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