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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish
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Citation:
Biol Open. 2018 Aug 10. pii: bio.035576. doi: 10.1242/bio.035576. [Epub ahead of print] Epub:
Yes Abstract:
Hemogen is a vertebrate transcription factor that performs important functions in erythropoiesis and testicular development and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Peters MJ, Parker SK, Grim J, Allard CAH, Levin J, Detrich HW 3rd. Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish. Biol Open. 2018 Aug 10. pii: bio.035576. doi: 10.1242/bio.035576. [Epub ahead of print]. |
A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors
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Citation:
Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17 Epub:
Not Epub Abstract:
Ewing's sarcoma treatment failures are associated with high mortality indicating a need for new therapeutic approaches. We... Delivery Method:
fatty acid conjugate & Endo-Porter Organism or Cell Type:
cell culture: TC-32 & CHLA-10 EFT lines and HEK293 renal epithelial control cells Citation Extract: Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL. A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors. Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17. |
Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes
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Citation:
Aging Dis. 2018 Aug 1;9(4):623-633. doi: 10.14336/AD.2017.0901. eCollection 2018 Aug Epub:
Not Epub Abstract:
Kif4a, a member of the kinesin superfamily, has been reported to participate in a series of cellular processes such as... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Tang F, Pan MH, Lu Y, Wan X, Zhang Y, Sun SC. Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes. Aging Dis. 2018 Aug 1;9(4):623-633. doi: 10.14336/AD.2017.0901. eCollection 2018 Aug. |
Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development
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Citation:
Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x Epub:
Not Epub Abstract:
As effectors of the Hippo signaling cascade, YAP1 and TAZ are transcriptional regulators playing important roles in development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Astone M, Lai JKH, Dupont S, Stainier DYR, Argenton F, Vettori A. Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x. |
Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS
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Citation:
Mol Ther Nucleic Acids. 2018;12:420-432. doi:10.1016/j.omtn.2018.05.019 Epub:
Not Epub Abstract:
DNA variants of the proteolipid protein 1 gene (PLP1) that shift PLP1/DM20 alternative splicing away from the PLP1 form toward... Delivery Method:
Endo-Porter, i.c.v. injection Organism or Cell Type:
cell culture: Oli-neu (immortalized oligodendrocyte precursor), mice Citation Extract: Tantzer S, Sperle K, Kenaley K, Taube J, Hobson GM. Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS. Mol Ther Nucleic Acids. 2018;12:420-432. doi:10.1016/j.omtn.2018.05.019. |
RES complex is associated with intron definition and required for zebrafish early embryogenesis
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Citation:
PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul Epub:
Not Epub Abstract:
Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ. RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul. |
Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration
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Citation:
Elife. 2018 Jun 28;7. pii: e34880. doi: 10.7554/eLife.34880 Epub:
Not Epub Abstract:
Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Collins MM, Maischein HM, Dufourcq P, Charpentier M, Blader P, Stainier DY. Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration. Elife. 2018 Jun 28;7. pii: e34880. doi: 10.7554/eLife.34880. |
Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development
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Citation:
Sci Rep. 2018 Jun 29;8(1):9840. doi: 10.1038/s41598-018-27791-6 Epub:
Not Epub Abstract:
Intussusceptive angiogenesis (IA) is a complementary method to sprouting angiogenesis (SA). The hallmark of IA is formation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Karthik S, Djukic T, Kim JD, Zuber B, Makanya A, Odriozola A, Hlushchuk R, Filipovic N, Jin SW, Djonov V. Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development. Sci Rep. 2018 Jun 29;8(1):9840. doi: 10.1038/s41598-018-27791-6. |
CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis
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Citation:
Brain. 2018 Jun 28. doi: 10.1093/brain/awy167. [Epub ahead of print] Epub:
Yes Abstract:
Autosomal recessive spinal muscular atrophy (SMA), the leading genetic cause of infant lethality, is caused by homozygous loss... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Janzen E, Mendoza-Ferreira N, Hosseinibarkooie S, Schneider S, Hupperich K, Tschanz T, Grysko V, Riessland M, Hammerschmidt M, Rigo F, Bennett CF, Kye MJ, Torres-Benito L, Wirth B. CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis. Brain. 2018 Jun 28. doi: 10.1093/brain/awy167. [Epub ahead of print]. |
Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development
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Citation:
Front Mol Neurosci. 2018 Jun 28;11:222. doi: 10.3389/fnmol.2018.00222. eCollection 2018 Epub:
Not Epub Abstract:
During development, immature blood vessel networks remodel to form a simplified and efficient vasculature to meet the demand... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Xu B, Chen Q, Yan Y, Du J, Du X. Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development. Front Mol Neurosci. 2018 Jun 28;11:222. doi: 10.3389/fnmol.2018.00222. eCollection 2018. |