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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Deep learning image recognition enables efficient genome editing in zebrafish by automated injections
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Citation:
PLoS One. 2019 Jan 7;14(1):e0202377. doi: 10.1371/journal.pone.0202377. eCollection 2019. Epub:
Not Epub Abstract:
One of the most popular techniques in zebrafish research is microinjection. This is a rapid and efficient way to genetically... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cordero-Maldonado ML, Perathoner S, van der Kolk K-J, Boland R, Heins-Marroquin U, Spaink HP, Meijer AH, Crawford AD, de Sonneville J. Deep learning image recognition enables efficient genome editing in zebrafish by automated injections. PLoS One. 2019 Jan 7;14(1):e0202377. doi: 10.1371/journal.pone.0202377. eCollection 2019.. |
Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish
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Citation:
J Endocrinol. 2014 Aug;222(2):229-41. doi: 10.1530/JOE-14-0178. Epub 2014 Jun 5 Epub:
Not Epub Abstract:
Type 2 diabetes, obesity, and metabolic syndrome are pathologies where insulin resistance plays a central role, and that affect... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Marín-Juez R, Jong-Raadsen S, Yang S, Spaink HP. Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish. J Endocrinol. 2014 Aug;222(2):229-41. doi: 10.1530/JOE-14-0178. Epub 2014 Jun 5. |
Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing
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Citation:
PLoS Pathog. 2018 Aug 2;14(8):e1007229. doi: 10.1371/journal.ppat.1007229. eCollection 2018 Aug Epub:
Not Epub Abstract:
In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rosowski EE, Raffa N, Knox BP, Golenberg N, Keller NP, Huttenlocher A. Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. PLoS Pathog. 2018 Aug 2;14(8):e1007229. doi: 10.1371/journal.ppat.1007229. eCollection 2018 Aug. |
De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism
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Citation:
Am J Hum Genet. 2018 Aug 6. pii: S0002-9297(18)30246-5. doi: 10.1016/j.ajhg.2018.07.019. [Epub ahead of print] Epub:
Yes Abstract:
Neurodevelopment is a transcriptionally orchestrated process. Cyclin K, a regulator of transcription encoded by CCNK, is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y. De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism. Am J Hum Genet. 2018 Aug 6. pii: S0002-9297(18)30246-5. doi: 10.1016/j.ajhg.2018.07.019. [Epub ahead of print]. |
Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates
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Citation:
Elife. 2018 Jul 31;7. pii: e36953. doi: 10.7554/eLife.36953 Epub:
Not Epub Abstract:
Signaling filopodia, termed cytonemes, are dynamic actin-based membrane structures that regulate the exchange of signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates. Elife. 2018 Jul 31;7. pii: e36953. doi: 10.7554/eLife.36953. |
Xbra and Smad-1 cooperate to activate the transcription of neural repressor ventx1.1 in Xenopus embryos
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Citation:
Sci Rep. 2018 Jul 30;8(1):11391. doi: 10.1038/s41598-018-29740-9 Epub:
Not Epub Abstract:
Crosstalk of signaling pathways play crucial roles in cell proliferation, cell differentiation, and cell fate determination for... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kumar S, Umair Z, Yoon J, Lee U, Kim SC, Park JB, Lee JY, Kim J. Xbra and Smad-1 cooperate to activate the transcription of neural repressor ventx1.1 in Xenopus embryos. Sci Rep. 2018 Jul 30;8(1):11391. doi: 10.1038/s41598-018-29740-9. |
MTG1 couples mitoribosome large subunit assembly with intersubunit bridge formation
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Citation:
Nucleic Acids Res. 2018 Jul 31. doi: 10.1093/nar/gky672. [Epub ahead of print] Epub:
Yes Abstract:
Mammalian mitochondrial ribosomes (mitoribosomes) synthesize 13 proteins, essential components of the oxidative phosphorylation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim HJ, Barrientos A. MTG1 couples mitoribosome large subunit assembly with intersubunit bridge formation. Nucleic Acids Res. 2018 Jul 31. doi: 10.1093/nar/gky672. [Epub ahead of print]. |
An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae
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Citation:
Front Cell Neurosci. 2018 Aug 21;12:257. doi: 10.3389/fncel.2018.00257. eCollection 2018. Epub:
Yes Abstract:
Zebrafish (Danio rerio) larvae are widely used to study otic functions because they possess all five typical vertebrate senses... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun P, Zhang Y, Zhao F, Wu J-P, Pun SH, Peng C, Du M, Vai MI, Liu D, Chen F. An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae. Front Cell Neurosci. 2018 Aug 21;12:257. doi: 10.3389/fncel.2018.00257. eCollection 2018. . |
The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis
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Citation:
PLoS Genet. 2018 Aug 17;14(8):e1007590. doi: 10.1371/journal.pgen.1007590. [Epub ahead of print] Epub:
Not Epub Abstract:
Small non-coding RNAs (sRNAs) such as microRNAs (miRNAs), small interfering RNAs (siRNAs) and piwi-interacting RNAs (piRNAs)... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Modepalli V, Fridrich A, Agron M, Moran Y. The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis. PLoS Genet. 2018 Aug 17;14(8):e1007590. doi: 10.1371/journal.pgen.1007590. [Epub ahead of print]. |
A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease
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Citation:
Sci Rep. 2018 Aug 17;8(1):12386. doi: 10.1038/s41598-018-30204-3 Epub:
Not Epub Abstract:
Heterotaxy syndrome (HTX) is characterized by left-right (LR) asymmetry disturbances associated with severe heart malformations... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li S, Liu S, Chen W, Yuan Y, Gu R, Song Y, Li J, Cao Y, Lin Y, Xu J, Wang H, Ma D, Ma X, Sheng W, Huang G. A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease. Sci Rep. 2018 Aug 17;8(1):12386. doi: 10.1038/s41598-018-30204-3. |