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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Zebrafish microRNA miR-210-5p inhibits primitive myelopoiesis by silencing foxj1b and slc3a2a mRNAs downstream of gata4/5/6 transcription factor genes

Authors:
Jia W, Liang D, Li N, Liu M, Dong Z, Li J, Dong X, Yue Y, Hu P, Yao J, Zhao Q
Citation:
J Biol Chem. 2018 Dec 28. pii: jbc.RA118.005079. doi: 10.1074/jbc.RA118.005079. [Epub ahead of print]
Epub:
Yes
Abstract:
Zebrafish gata4/5/6 genes encode transcription factors that lie on the apex of the regulatory hierarchy in primitive...
Link:
http://www.jbc.org/content/early/2018/12/28/jbc.RA118.005079.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jia W, Liang D, Li N, Liu M, Dong Z, Li J, Dong X, Yue Y, Hu P, Yao J, Zhao Q. Zebrafish microRNA miR-210-5p inhibits primitive myelopoiesis by silencing foxj1b and slc3a2a mRNAs downstream of gata4/5/6 transcription factor genes. J Biol Chem. 2018 Dec 28. pii: jbc.RA118.005079. doi: 10.1074/jbc.RA118.005079. [Epub ahead of print].

Photoreceptor Progenitors Depend Upon Coordination of gdf6a, thrβ, and tbx2b to Generate Precise Populations of Cone Photoreceptor Subtypes

Authors:
DuVal MG, Allison WT
Citation:
Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6089-6101. doi: 10.1167/iovs.18-24461
Epub:
Not Epub
Abstract:
Purpose: Replacing cone photoreceptors, the units of the retina necessary for daytime vision, depends upon the successful...
Link:
https://iovs.arvojournals.org/article.aspx?articleid=2719602
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
DuVal MG, Allison WT. Photoreceptor Progenitors Depend Upon Coordination of gdf6a, thrβ, and tbx2b to Generate Precise Populations of Cone Photoreceptor Subtypes. Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6089-6101. doi: 10.1167/iovs.18-24461.

Fabrication of a novel DNA affinity biosensor based on hybridisation induced current by electrostatic repulsion of silicotungstic acid as a redox indicator

Authors:
Kumari P, Adeloju SB
Citation:
Talanta. 2019 Mar 1;194:127-133. doi: 10.1016/j.talanta.2018.09.074. Epub 2018 Sep 20
Epub:
Not Epub
Abstract:
We report on a novel DNA affinity biosensor which utilises the capture of a neutral charged single stranded (ss) morpholino DNA...
Link:
https://www.sciencedirect.com/science/article/pii/S0039914018309858
Citation Extract:
Kumari P, Adeloju SB. Fabrication of a novel DNA affinity biosensor based on hybridisation induced current by electrostatic repulsion of silicotungstic acid as a redox indicator. Talanta. 2019 Mar 1;194:127-133. doi: 10.1016/j.talanta.2018.09.074. Epub 2018 Sep 20.

The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio)

Authors:
Hughes MC, Zimmer AM, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2019 Jan 2. doi: 10.1152/ajpregu.00315.2018. [Epub ahead of print]
Epub:
Yes
Abstract:
Purely diffusive O2 transport typically is insufficient to sustain aerobic metabolism in most multicellular organisms. In...
Link:
https://www.physiology.org/doi/abs/10.1152/ajpregu.00315.2018
Organism or Cell Type:
zebrafish
Citation Extract:
Hughes MC, Zimmer AM, Perry SF. The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2019 Jan 2. doi: 10.1152/ajpregu.00315.2018. [Epub ahead of print].

Morpholino Oligonucleotide Crosslinked Hydrogels as Portable Optical Oligonucleotide Biosensors

Authors:
Langford G, Raeburn J, Ferrier DC, Hands PJW, Shaver MP
Citation:
ACS Sens. 2018 Dec 28. doi: 10.1021/acssensors.8b01208. [Epub ahead of print]
Epub:
Yes
Abstract:
Morpholino Oligonucleotides (MOs), an uncharged DNA analogue, are functionalized with an acrylamide moiety and incorporated...
Link:
https://pubs.acs.org/doi/10.1021/acssensors.8b01208
Citation Extract:
Langford G, Raeburn J, Ferrier DC, Hands PJW, Shaver MP. Morpholino Oligonucleotide Crosslinked Hydrogels as Portable Optical Oligonucleotide Biosensors. ACS Sens. 2018 Dec 28. doi: 10.1021/acssensors.8b01208. [Epub ahead of print].

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

Authors:
Cagnetta R, Wong HH-W, Frese CK, Mallucci GR, Krijgsveld J, Holt CE
Citation:
Molec Cell. 2018;[Epub] doi:doi.org/10.1016/j.molcel.2018.11.013
Epub:
Yes
Abstract:
Local translation is rapidly regulated by extrinsic signals during neural wiring, but its control mechanisms remain elusive....
Link:
https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30983-3
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cagnetta R, Wong HH-W, Frese CK, Mallucci GR, Krijgsveld J, Holt CE. Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring. Molec Cell. 2018;[Epub] doi:doi.org/10.1016/j.molcel.2018.11.013.

Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms

Authors:
Yang X, Li J, Fang Y, Zhang Z, Jin D, Chen X, Zhao Y, Li M, Huan L, Kent TA, Dong JF, Jiang R, Yang S, Jin L, Zhang J, Zhong TP, Yu F
Citation:
Circ Genom Precis Med. 2018 Jul;11(7):e002099. doi: 10.1161/CIRCGEN.117.002099
Epub:
Not Epub
Abstract:
BACKGROUND: Intracranial aneurysm (IA) is usually a late-onset disease, affecting 1% to 3% of the general population and...
Link:
https://www.ahajournals.org/doi/10.1161/CIRCGEN.117.002099
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang X, Li J, Fang Y, Zhang Z, Jin D, Chen X, Zhao Y, Li M, Huan L, Kent TA, Dong JF, Jiang R, Yang S, Jin L, Zhang J, Zhong TP, Yu F. Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms. Circ Genom Precis Med. 2018 Jul;11(7):e002099. doi: 10.1161/CIRCGEN.117.002099.

PCP-dependent transcellular regulation of actomyosin oscillation facilitates convergent extension of vertebrate tissue

Authors:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB
Citation:
Dev Biol. 2018 Dec 20. pii: S0012-1606(18)30690-0. doi: 10.1016/j.ydbio.2018.12.017. [Epub ahead of print]
Epub:
Yes
Abstract:
Oscillatory flows of actomyosin play a key role in the migration of single cells in culture and in collective cell movements in...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618306900
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB. PCP-dependent transcellular regulation of actomyosin oscillation facilitates convergent extension of vertebrate tissue. Dev Biol. 2018 Dec 20. pii: S0012-1606(18)30690-0. doi: 10.1016/j.ydbio.2018.12.017. [Epub ahead of print].

Homeogene emx1 is required for nephron distal segment development in zebrafish

Authors:
Morales EE, Handa N, Drummond BE, Chambers JM, Marra AN, Addiego A, Wingert RA
Citation:
Sci Rep. 2018 Dec 21;8(1):18038. doi: 10.1038/s41598-018-36061-4
Epub:
Not Epub
Abstract:
Vertebrate kidneys contain nephron functional units where specialized epithelial cell types are organized into segments with...
Link:
https://www.nature.com/articles/s41598-018-36061-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morales EE, Handa N, Drummond BE, Chambers JM, Marra AN, Addiego A, Wingert RA. Homeogene emx1 is required for nephron distal segment development in zebrafish. Sci Rep. 2018 Dec 21;8(1):18038. doi: 10.1038/s41598-018-36061-4.

Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function

Authors:
Wen XY, Tarailo-Graovac M, Brand-Arzamendi K, Willems A, Rakic B, Huijben K, Da Silva A, Pan X, El-Rass S, Ng R, Selby K, Philip AM, Yun J, Ye XC, Ross CJ, Lehman AM, Zijlstra F, Bakar AA, Drögemöller B, Moreland J, Wasserman WW, Vallance H, van Scherpenzeel M, Karbassi F, Hoskings M, Engelke U, de Brouwer A, Wevers RA, Pshezhetsky AV, van Karnebeek CD, Lefeber DJ
Citation:
JCI Insight. 2018 Dec 20;3(24). pii: 122373. doi: 10.1172/jci.insight.122373. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Sialic acids are important components of glycoproteins and glycolipids essential for cellular communication, infection, and...
Link:
https://insight.jci.org/articles/view/122373
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wen XY, Tarailo-Graovac M, Brand-Arzamendi K, Willems A, Rakic B, Huijben K, Da Silva A, Pan X, El-Rass S, Ng R, Selby K, Philip AM, Yun J, Ye XC, Ross CJ, Lehman AM, Zijlstra F, Bakar AA, Drögemöller B, Moreland J, Wasserman WW, Vallance H, van Scherpenzeel M, Karbassi F, Hoskings M, Engelke U, de Brouwer A, Wevers RA, Pshezhetsky AV, van Karnebeek CD, Lefeber DJ. Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function. JCI Insight. 2018 Dec 20;3(24). pii: 122373. doi: 10.1172/jci.insight.122373. [Epub ahead of print].

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