You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Systemic Injection of Peptide-PMOs into Humanized DMD Mice and Evaluation by RT-PCR and ELISA
|
Citation:
Methods Mol Biol. 2018;1828:263-273. doi: 10.1007/978-1-4939-8651-4_16 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder due to the lack of dystrophin production. The disease is... Delivery Method:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_16 Organism or Cell Type:
mice Citation Extract: Melo D, Maruyama R, Yokota T. Systemic Injection of Peptide-PMOs into Humanized DMD Mice and Evaluation by RT-PCR and ELISA. Methods Mol Biol. 2018;1828:263-273. doi: 10.1007/978-1-4939-8651-4_16. |
Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment
|
Citation:
Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13 Epub:
Not Epub Abstract:
Duplications of one or more dystrophin exons that disrupt the reading frame account for about 15% of all Duchenne cases, and... Delivery Method:
peptide-linked Citation Extract: Greer K, Fletcher S, Wilton SD. Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment. Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13. |
In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient
|
Citation:
Methods Mol Biol. 2018;1828:151-163. doi: 10.1007/978-1-4939-8651-4_9 Epub:
Not Epub Abstract:
Antisense oligonucleotide induced exon skipping emerges as a promising therapeutic strategy for patients suffering from a... Organism or Cell Type:
cell culture: canine and human fibroblasts differentiated to myotubes Citation Extract: Nakamura A, Aoki Y, Tsoumpra M, Yokota T, Takeda S. In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient. Methods Mol Biol. 2018;1828:151-163. doi: 10.1007/978-1-4939-8651-4_9. |
Tips to Design Effective Splice-Switching Antisense Oligonucleotides for Exon Skipping and Exon Inclusion
|
Citation:
Methods Mol Biol. 2018;1828:79-90. doi: 10.1007/978-1-4939-8651-4_5 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping and exon inclusion have proven to be powerful tools for treating neuromuscular diseases. The... Citation Extract: Maruyama R, Yokota T. Tips to Design Effective Splice-Switching Antisense Oligonucleotides for Exon Skipping and Exon Inclusion. Methods Mol Biol. 2018;1828:79-90. doi: 10.1007/978-1-4939-8651-4_5. |
Bapx1 is required for jaw joint development in amphibians
|
Citation:
Evol Dev. 2018 Nov;20(6):192-206. doi:10.1111/ede.12267 Epub:
Not Epub Abstract:
The acquisition of a movable jaw and a jaw joint are key events in gnathostome evolution. Jaws are derived from the neural... Citation Extract: Lukas P, Olsson L.
. Bapx1 is required for jaw joint development in amphibians. Evol Dev. 2018 Nov;20(6):192-206. doi:10.1111/ede.12267. |
Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum
|
Citation:
Anal Chem. 2018 Aug 29. doi: 10.1021/acs.analchem.8b02330. [Epub ahead of print] Epub:
Yes Abstract:
Micro total analysis systems (μTAS) have been extensively developed for the detection of nucleic acids (NAs) in resource-... Citation Extract: Ouyang W, Li Z, Han J. Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum. Anal Chem. 2018 Aug 29. doi: 10.1021/acs.analchem.8b02330. [Epub ahead of print]. |
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa
|
Citation:
PLoS Genet. 2018;14(8):e1007504. doi:10.1371/journal.pgen.1007504 Epub:
Not Epub Abstract:
We identified a homozygous missense alteration (c.75C>A, p.D25E) in CLCC1, encoding a presumptive intracellular chloride... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li L, Jiao X, D’Atri I, Ono F, Nelson R, Chan C-C, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Akdemir ZHC, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Firoz Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF. Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS Genet. 2018;14(8):e1007504. doi:10.1371/journal.pgen.1007504. |
TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration
|
Citation:
Nat Comm. 2018;9:3491. doi:10.1038/s41467-018-05924-9 Epub:
Not Epub Abstract:
Although Eph-ephrin signalling has been implicated in the migration of cranial neural crest (CNC) cells, it is still unclear... Organism or Cell Type:
Xenopus Citation Extract: Yoon J, Hwang Y-S, Lee M, Sun J, Cho HJ, Knapik L, Daar IO. TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration. Nat Comm. 2018;9:3491. doi:10.1038/s41467-018-05924-9. |
Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia
|
Citation:
Nature. 2018:[Epub ahead of print] doi:10.1038/s41586-018-0465-8DO Epub:
Yes Abstract:
DNA mutations are known cancer drivers. Here we investigated whether mRNA events that are upregulated in cancer can... Organism or Cell Type:
cell culture: HeLa Citation Extract: Lee S-H, Singh I, Tisdale S, Abdel-Wahab O, Leslie CS, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018:[Epub ahead of print] doi:10.1038/s41586-018-0465-8DO. |
De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome
|
Citation:
Am J Hum Genet. 2018 Aug 22. pii: S0002-9297(18)30247-7. doi: 10.1016/j.ajhg.2018.07.020. [Epub ahead of print] Epub:
Yes Abstract:
Inherited bone-marrow-failure syndromes (IBMFSs) include heterogeneous genetic disorders characterized by bone-marrow failure,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E. De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome. Am J Hum Genet. 2018 Aug 22. pii: S0002-9297(18)30247-7. doi: 10.1016/j.ajhg.2018.07.020. [Epub ahead of print]. |