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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Eteplirsen treatment attenuates respiratory decline in ambulatory and non-ambulatory patients with Duchenne muscular dystrophy
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Citation:
Neuromusc Disord. 2018;28:P125. doi:10.1016/j.nmd.2018.06.153 Epub:
Not Epub Abstract:
no abstract available Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Khan N, Han L, Kinane B, Gordish-Dressman H, Lowes L, McDonald C. Eteplirsen treatment attenuates respiratory decline in ambulatory and non-ambulatory patients with Duchenne muscular dystrophy. Neuromusc Disord. 2018;28:P125. doi:10.1016/j.nmd.2018.06.153. |
Eteplirsen is well tolerated in adults with mild or moderate renal impairment
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Citation:
Neuromusc Disord. 2018;28:P124. doi:10.1016/j.nmd.2018.06.152 Epub:
Not Epub Abstract:
no abstract available
Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Mix C, Naughton N, Forte S. Eteplirsen is well tolerated in adults with mild or moderate renal impairment. Neuromusc Disord. 2018;28:P124. doi:10.1016/j.nmd.2018.06.152. |
Humoral and cell mediated immune response to new dystrophin after morpholino-induced exon skipping therapy in dystrophin-deficient mdx mice
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Citation:
Neuromusc Disord. 2018;28:S90. doi:10.1016/j.nmd.2018.06.238 Epub:
Not Epub Abstract:
Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne... Organism or Cell Type:
mice mdx Citation Extract: Nagaraju K, Vila M, Novak J, Boehler J, Hogarth M, Zhang A, Kinder T, Mazala D, Klimek MB, Fiorillo A, van den Anker J, Hathout Y, Hoffman E, Partridge T. Humoral and cell mediated immune response to new dystrophin after morpholino-induced exon skipping therapy in dystrophin-deficient mdx mice. Neuromusc Disord. 2018;28:S90. doi:10.1016/j.nmd.2018.06.238. |
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis
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Citation:
Proc Natl Acad Sci U S A. 2018 Sep 12. pii: 201812117. doi: 10.1073/pnas.1812117115. [Epub ahead of print] Epub:
Yes Abstract:
The Xenopus laevis embryo has been subjected to almost saturating screens for molecules specifically expressed in dorsal... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM. Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. Proc Natl Acad Sci U S A. 2018 Sep 12. pii: 201812117. doi: 10.1073/pnas.1812117115. [Epub ahead of print]. |
Zebrafish snai2 mutants fail to phenocopy morphant phenotypes
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Citation:
PLoS One. 2018 Sep 12;13(9):e0202747. doi: 10.1371/journal.pone.0202747. eCollection 2018 Epub:
Not Epub Abstract:
Snail2 is a zinc-finger transcription factor best known to repress expression of genes encoding cell adherence proteins to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bickers C, Española SD, Grainger S, Pouget C, Traver D. Zebrafish snai2 mutants fail to phenocopy morphant phenotypes. PLoS One. 2018 Sep 12;13(9):e0202747. doi: 10.1371/journal.pone.0202747. eCollection 2018. |
The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes
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Citation:
J Am Soc Nephrol. 2018 Aug;29(8):2110-2122. doi: 10.1681/ASN.2017121338. Epub 2018 Jul 12 Epub:
Not Epub Abstract:
BACKGROUND: We previously reported that mutations in the anillin (ANLN) gene cause familial forms of FSGS. ANLN is an F-actin... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hall G, Lane BM, Khan K, Pediaditakis I, Xiao J, Wu G, Wang L, Kovalik ME, Chryst-Stangl M, Davis EE, Spurney RF, Gbadegesin RA. The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes. J Am Soc Nephrol. 2018 Aug;29(8):2110-2122. doi: 10.1681/ASN.2017121338. Epub 2018 Jul 12. |
Bypassing Glutamic Acid Decarboxylase 1 (Gad1) Induced Craniofacial Defects with a Photoactivatable Translation Blocker Morpholino
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Citation:
ACS Chem Neurosci. 2018 Sep 10. doi: 10.1021/acschemneuro.8b00231. [Epub ahead of print] Epub:
Yes Abstract:
γ-Amino butyric acid (GABA) mediated signaling is critical in the central and enteric nervous systems, pancreas, lungs and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: O'Connor MJ, Beebe LL, Deodato D, Ball RE, Page AT, VanLeuven AJ, Harris KT, Park S, Hariharan V, Lauderdale JD, Dore TM. Bypassing Glutamic Acid Decarboxylase 1 (Gad1) Induced Craniofacial Defects with a Photoactivatable Translation Blocker Morpholino. ACS Chem Neurosci. 2018 Sep 10. doi: 10.1021/acschemneuro.8b00231. [Epub ahead of print]. |
Control of Hexamerization, Assembly, and Excluded Strand Specificity for the Sulfolobus solfataricus MCM Helicase
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Citation:
Biochemistry. 2018 Sep 10. doi: 10.1021/acs.biochem.8b00766. [Epub ahead of print] Epub:
Yes Abstract:
There has been increasing evidence supporting a steric exclusion and wrapping (SEW) model for DNA unwinding in which hexameric... Citation Extract: Graham BW, Bougoulias ME, Dodge KL, Thaxton CT, Olaso D, Tao Y, Young NL, Marshall AG, Trakselis MA. Control of Hexamerization, Assembly, and Excluded Strand Specificity for the Sulfolobus solfataricus MCM Helicase. Biochemistry. 2018 Sep 10. doi: 10.1021/acs.biochem.8b00766. [Epub ahead of print]. |
Drug-Free Macromolecular Therapeutics Exhibit Amplified Apoptosis in G2/M Phase Arrested Cells
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Citation:
J Drug Target. 2018 Sep 10:1-18. doi: 10.1080/1061186X.2018.1521414. [Epub ahead of print] Epub:
Not Epub Abstract:
Drug-free macromolecular therapeutics (DFMT) have been recently developed to treat non-Hodgkin lymphoma (NHL). It is a... Citation Extract: Li L, Yang J, Wang J, Kopeček J. Drug-Free Macromolecular Therapeutics Exhibit Amplified Apoptosis in G2/M Phase Arrested Cells. J Drug Target. 2018 Sep 10:1-18. doi: 10.1080/1061186X.2018.1521414. [Epub ahead of print]. |
Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice
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Citation:
Asian J Androl. 2018 Sep 7. doi: 10.4103/aja.aja_65_18. [Epub ahead of print] Epub:
Yes Abstract:
While it is known that spermatogonial stem cells (SSCs) initiate the production of male germ cells, the mechanisms of SSC self-... Organism or Cell Type:
cell culture: mouse spermatogonial stem cells (SSC), mouse testicuar explants Citation Extract: Shen C, Yu J, Zhang X, Liu CC, Guo YS, Zhu JW, Zhang K, Yu Y, Gao TT, Yang SM, Li H, Zheng B, Huang XY. Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice. Asian J Androl. 2018 Sep 7. doi: 10.4103/aja.aja_65_18. [Epub ahead of print]. |