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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Loss of Leucyl-tRNA synthetase b leads to ILFS1-like symptoms in zebrafish

Authors:
Wang Z, Song J, Luo L, Ma J
Citation:
Biochem Biophys Res Commun. 2018 Sep 24. pii: S0006-291X(18)32067-9. doi: 10.1016/j.bbrc.2018.09.133. [Epub ahead of print]
Epub:
Yes
Abstract:
Leucyl-tRNA synthetase (LARS) is a kind of aminoacyl-tRNA synthetases (aaRSs), which is important for protein synthesis....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Z, Song J, Luo L, Ma J. Loss of Leucyl-tRNA synthetase b leads to ILFS1-like symptoms in zebrafish. Biochem Biophys Res Commun. 2018 Sep 24. pii: S0006-291X(18)32067-9. doi: 10.1016/j.bbrc.2018.09.133. [Epub ahead of print].

Cell type-specific expression profiling unravels the development and evolution of stinging cells in sea anemone

Authors:
Sunagar K, Columbus-Shenkar YY, Fridrich A, Gutkovich N, Aharoni R, Moran Y
Citation:
BMC Biology. 2018;16:108. doi:10.1186/s12915-018-0578-4
Epub:
Not Epub
Abstract:
Background: Cnidocytes are specialized cells that define the phylum Cnidaria. They possess an "explosive" organelle...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Sunagar K, Columbus-Shenkar YY, Fridrich A, Gutkovich N, Aharoni R, Moran Y. Cell type-specific expression profiling unravels the development and evolution of stinging cells in sea anemone. BMC Biology. 2018;16:108. doi:10.1186/s12915-018-0578-4.

Implementing Morpholino-Based Nucleic Acid Sensing on a Portable Surface Plasmon Resonance Instrument for Future Application in Environmental Monitoring

Authors:
Bagi A, Soelberg SD, Furlong CE, Baussant T
Citation:
Sensors. 2018;18(10):3259. doi:10.3390/s18103259
Epub:
Not Epub
Abstract:
A portable surface plasmon resonance (SPR) instrument was tested for the first time for the detection of oligonucleotide...
Citation Extract:
Bagi A, Soelberg SD, Furlong CE, Baussant T. Implementing Morpholino-Based Nucleic Acid Sensing on a Portable Surface Plasmon Resonance Instrument for Future Application in Environmental Monitoring. Sensors. 2018;18(10):3259. doi:10.3390/s18103259.

Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration

Authors:
Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A
Citation:
Nature Struct & Molec Biol. 2018;[epub ahead of print] doi:10.1038/s41594-018-0129-2
Epub:
Yes
Abstract:
During liver regeneration, most new hepatocytes arise via self-duplication; yet, the underlying mechanisms that drive...
Organism or Cell Type:
cell culture: AML-12
Citation Extract:
Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A. Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration. Nature Struct & Molec Biol. 2018;[epub ahead of print] doi:10.1038/s41594-018-0129-2.

Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo

Authors:
Kotini M, Barriga EH, Leslie J, Gentzel M, Rauschenberger V, Schambon A, Mayor R
Citation:
Nat Commun. 2018 Sep 21;9(1):3846. doi: 10.1038/s41467-018-06368-x
Epub:
Not Epub
Abstract:
Connexins are the primary components of gap junctions, providing direct links between cells under many physiological processes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kotini M, Barriga EH, Leslie J, Gentzel M, Rauschenberger V, Schambon A, Mayor R. Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo. Nat Commun. 2018 Sep 21;9(1):3846. doi: 10.1038/s41467-018-06368-x.

Expression and function of lncRNA MALAT-1 in the embryonic development of zebrafish

Authors:
Wu M, Zhang S, Chen X, Xu H, Li X
Citation:
Gene. 2018 Sep 21. pii: S0378-1119(18)30996-X. doi: 10.1016/j.gene.2018.09.037. [Epub ahead of print]
Epub:
Yes
Abstract:
Long non-coding RNAs (lncRNAs) are RNA molecules with a transcript length of >200 nt which do not encode proteins, however,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu M, Zhang S, Chen X, Xu H, Li X. Expression and function of lncRNA MALAT-1 in the embryonic development of zebrafish. Gene. 2018 Sep 21. pii: S0378-1119(18)30996-X. doi: 10.1016/j.gene.2018.09.037. [Epub ahead of print].

CTP synthase knockdown during early development distorts the nascent vertebral column and causes fluid retention in multiple tissues in zebrafish

Authors:
Dzaki N, Wahab W, Azlan A, Azzam G
Citation:
Biochem Biophys Res Commun. 2018 Sep 18. pii: S0006-291X(18)31999-5. doi: 10.1016/j.bbrc.2018.09.074. [Epub ahead of print]
Epub:
Yes
Abstract:
CTP Synthase (CTPS) is a metabolic enzyme that is recognized as a catalyst for nucleotide, phospholipid and sialoglycoprotein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dzaki N, Wahab W, Azlan A, Azzam G. CTP synthase knockdown during early development distorts the nascent vertebral column and causes fluid retention in multiple tissues in zebrafish. Biochem Biophys Res Commun. 2018 Sep 18. pii: S0006-291X(18)31999-5. doi: 10.1016/j.bbrc.2018.09.074. [Epub ahead of print].

Perturbations of BMP/TGF-β and VEGF/VEGFR signalling pathways in non-syndromic sporadic brain arteriovenous malformations (BAVM)

Authors:
Wang K, Zhao S, Liu B, Zhang Q, Li Y, Liu J, Shen Y, Ding X, Lin J, Wu Y, Yan Z, Chen J, Li X, Song X, Niu Y, Liu J, Chen W, Ming Y, Du R, Chen C, Long B, Zhang Y, Tong X, Zhang S, Posey JE, Zhang B, Wu Z, Wythe JD, Liu P, Lupski JR, Yang X, Wu N
Citation:
J Med Genet. 2018 Aug 17. pii: jmedgenet-2017-105224. doi: 10.1136/jmedgenet-2017-105224. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Brain arteriovenous malformations (BAVM) represent a congenital anomaly of the cerebral vessels with a prevalence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang K, Zhao S, Liu B, Zhang Q, Li Y, Liu J, Shen Y, Ding X, Lin J, Wu Y, Yan Z, Chen J, Li X, Song X, Niu Y, Liu J, Chen W, Ming Y, Du R, Chen C, Long B, Zhang Y, Tong X, Zhang S, Posey JE, Zhang B, Wu Z, Wythe JD, Liu P, Lupski JR, Yang X, Wu N. Perturbations of BMP/TGF-β and VEGF/VEGFR signalling pathways in non-syndromic sporadic brain arteriovenous malformations (BAVM). J Med Genet. 2018 Aug 17. pii: jmedgenet-2017-105224. doi: 10.1136/jmedgenet-2017-105224. [Epub ahead of print].

Genome Editing Reveals Idiosyncrasy of CNGA2 Ion Channel-Directed Antibody Immunoreactivity Toward Oxytocin

Authors:
Blechman J, Anbalagan S, Matthews GG, Levkowitz G
Citation:
Front Cell Dev Biol. 2018. doi:10.3389/fcell.2018.00117
Epub:
Not Epub
Abstract:
Presynaptic cGMP-gated ion (CNG) channels positively or negatively modulate neurotransmitter secretion as well as the strength...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blechman J, Anbalagan S, Matthews GG, Levkowitz G. Genome Editing Reveals Idiosyncrasy of CNGA2 Ion Channel-Directed Antibody Immunoreactivity Toward Oxytocin. Front Cell Dev Biol. 2018. doi:10.3389/fcell.2018.00117.

A transgenic zebrafish model for in vivo long-term imaging of retinotectal synaptogenesis

Authors:
Du X-f, Xu B, Zhang Y, Chen M-j, Du J-l
Citation:
Sci Rep. 2018;8:14077. doi:10.1038/s41598-018-32409-y
Epub:
Not Epub
Abstract:
The retinotectal synapse in larval zebrafish, combined with live time-lapse imaging, provides an advantageous model for study...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Du X-f, Xu B, Zhang Y, Chen M-j, Du J-l. A transgenic zebrafish model for in vivo long-term imaging of retinotectal synaptogenesis. Sci Rep. 2018;8:14077. doi:10.1038/s41598-018-32409-y.

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