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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
CREST in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, and synaptic plasticity
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Citation:
J Neurosci. 2018. doi:10.1523/JNEUROSCI.2911-17.2018 Epub:
Not Epub Abstract:
Epigenetic mechanisms result in persistent changes at the cellular level that can lead to long-lasting behavioral adaptations.... Delivery Method:
nucleus accumbens infusion Organism or Cell Type:
Rattus (rat) Citation Extract: Alaghband Y, Kramár E, Kwapis JL, Kim ES, Hemstedt TJ, López AJ, White AO, Al-Kachak A, Aimiuwu OV, Bodinayake KK, Oparaugo NC, Han J, Lattal KM, Wood MA. CREST in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, and synaptic plasticity. J Neurosci. 2018. doi:10.1523/JNEUROSCI.2911-17.2018. |
Stromal interaction molecule 1 is required for neonatal testicular development in mice
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Citation:
Biochem Biophys Res Commun. 2018 Sep 14. pii: S0006-291X(18)31962-4. doi: 10.1016/j.bbrc.2018.09.044. [Epub ahead of print] Epub:
Yes Abstract:
Stromal interaction molecule 1 (STIM1) is a transmembrane endoplasmic reticulum protein, and it serves as a Ca2+ sensor and... Organism or Cell Type:
explant: mouse neonatal testis culture Citation Extract: Shen C, Zhang K, Yu J, Guo Y, Gao T, Liu Y, Zhang X, Chen X, Yu Y, Cheng H, Zheng A, Li H, Huang X, Ding X, Zheng B. Stromal interaction molecule 1 is required for neonatal testicular development in mice. Biochem Biophys Res Commun. 2018 Sep 14. pii: S0006-291X(18)31962-4. doi: 10.1016/j.bbrc.2018.09.044. [Epub ahead of print]. |
Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish
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Citation:
iScience. 2018;7:68-84. doi:10.1016/j.isci.2018.08.008 Epub:
Not Epub Abstract:
Histone deacetylases (Hdacs) play significant roles in cellular homeostasis and tissue differentiation. Hdacs are well... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Mitra S, Sharma P, Kaur S, Khursheed MA, Gupta S, Ahuja R, Kurup AJ, Chaudhary M, Ramachandran R. Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish. iScience. 2018;7:68-84. doi:10.1016/j.isci.2018.08.008. |
Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance
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Citation:
J Am Soc Nephrol. 2015 Sep;26(9):2118-28. doi: 10.1681/ASN.2014080819. Epub 2015 Jan 2 Epub:
Not Epub Abstract:
The Wilms' tumor suppressor gene 1 (WT1) encodes a zinc finger transcription factor. Mutation of WT1 in humans leads to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dong L, Pietsch S, Tan Z, Perner B, Sierig R, Kruspe D, Groth M, Witzgall R, Gröne HJ, Platzer M, Englert C. Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance. J Am Soc Nephrol. 2015 Sep;26(9):2118-28. doi: 10.1681/ASN.2014080819. Epub 2015 Jan 2. |
MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo
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Citation:
PLoS Genet. 2018;14(9):e1007621. doi:10.1371/journal.pgen.1007621 Epub:
Not Epub Abstract:
In the sea urchin embryo, specification of the dorsal-ventral axis critically relies on the spatially restricted expression of... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Molina MD, Quirin M, Haillot E, De Crozé N, Range R, Rouel M, Jimenez F, Amrouche R, Chessel A, Lepage T. MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo. PLoS Genet. 2018;14(9):e1007621. doi:10.1371/journal.pgen.1007621. |
Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury
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Citation:
J Am Soc Nephrol. 2014 Jun;25(6):1171-86. doi: 10.1681/ASN.2013040433. Epub 2014 Feb 7. Erratum in: J Am Soc Nephrol. 2014 Aug;25(8):1884 Epub:
Not Epub Abstract:
Ischemia reperfusion injury (IRI) causes tissue and organ injury, in part, through alterations in tissue blood flow and the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: rat aortic VSMC Citation Extract: Yao M, Rogers NM, Csányi G, Rodriguez AI, Ross MA, St Croix C, Knupp H, Novelli EM, Thomson AW, Pagano PJ, Isenberg JS. Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury. J Am Soc Nephrol. 2014 Jun;25(6):1171-86. doi: 10.1681/ASN.2013040433. Epub 2014 Feb 7. Erratum in: J Am Soc Nephrol. 2014 Aug;25(8):1884. |
Polycystin-1 regulates bone development through an interaction with the transcriptional co-activator taz
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Citation:
Hum Mol Genet. 2018 Sep 12. doi: 10.1093/hmg/ddy322. [Epub ahead of print] Epub:
Yes Abstract:
Polycystin-1 (PC1), encoded by the PKD1 gene that is mutated in Autosomal Dominant Polycystic Kidney disease, regulates a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Merrick D, Mistry K, Wu J, Gresko N, Baggs JE, Hogenesch JB, Sun Z, Caplan MJ. Polycystin-1 regulates bone development through an interaction with the transcriptional co-activator taz. Hum Mol Genet. 2018 Sep 12. doi: 10.1093/hmg/ddy322. [Epub ahead of print]. |
A Japanese phase I/II study of NS-065/NCNP-01, exon 53 skipping drug, in patients with Duchenne muscular dystrophy - a dose-finding study
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Citation:
Neuromusc Disord. 2018;28:P129. doi:10.1016/j.nmd.2018.06.157 Epub:
Not Epub Abstract:
no abstract available Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Komaki H, Takeshima Y, Matsumura T, Ozasa S, Funato M, Egawa Y, Takeda S. A Japanese phase I/II study of NS-065/NCNP-01, exon 53 skipping drug, in patients with Duchenne muscular dystrophy - a dose-finding study. Neuromusc Disord. 2018;28:P129. doi:10.1016/j.nmd.2018.06.157. |
Respiratory function decline in eteplirsen-treated patients diverges from natural history comparators over time
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Citation:
Neuromusc Disord. 2018;28:P126. doi:10.1016/j.nmd.2018.06.154 Epub:
Not Epub Abstract:
no abstract available Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Khan N, Han L, Kinane B, Gordish-Dressman H, Lowes L, McDonald C. Respiratory function decline in eteplirsen-treated patients diverges from natural history comparators over time. Neuromusc Disord. 2018;28:P126. doi:10.1016/j.nmd.2018.06.154. |
A phase II, dose finding study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of NS-065/NCNP-01 in boys with Duchenne muscular dystrophy
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Citation:
Neuromusc Disord. 2018;28(Suppl 2):S67-S68. doi:10.1016/j.nmd.2018.06.156 Epub:
Not Epub Abstract:
no abstract available
Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Clemens P, Rao V, Connolly A, Harper A, Mah J, Smith E, McDonald C, Morgenroth L, Osaki H, Hoffman E. A phase II, dose finding study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of NS-065/NCNP-01 in boys with Duchenne muscular dystrophy. Neuromusc Disord. 2018;28(Suppl 2):S67-S68. doi:10.1016/j.nmd.2018.06.156. |