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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus

Authors:
Nath PR, Gangaplara A, Pal-Nath D, Mandal A, Maric D, Sipes JM, Cam M, Shevach EM, Roberts DD
Citation:
Front Immunol. 2018;9:2985. doi:10.3389/fimmu.2018.02985
Epub:
Not Epub
Abstract:
CD47 is a ubiquitous cell surface receptor that directly regulates T cell immunity by interacting with its inhibitory ligand...
Delivery Method:
i.p. injection
Organism or Cell Type:
mice
Citation Extract:
Nath PR, Gangaplara A, Pal-Nath D, Mandal A, Maric D, Sipes JM, Cam M, Shevach EM, Roberts DD. CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus. Front Immunol. 2018;9:2985. doi:10.3389/fimmu.2018.02985.

Biallelic mutations in USP45, encoding a deubiquitinating enzyme, are associated with Leber congenital amaurosis

Authors:
Yi Z, Ouyang J, Sun W, Xiao X, Li S, Jia X, Wang P, Zhang Q
Citation:
J Med Genet. 2018 Dec 20. pii: jmedgenet-2018-105709. doi: 10.1136/jmedgenet-2018-105709. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Leber congenital amaurosis (LCA) is the earliest and most severe form of inherited retinal dystrophies. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yi Z, Ouyang J, Sun W, Xiao X, Li S, Jia X, Wang P, Zhang Q. Biallelic mutations in USP45, encoding a deubiquitinating enzyme, are associated with Leber congenital amaurosis. J Med Genet. 2018 Dec 20. pii: jmedgenet-2018-105709. doi: 10.1136/jmedgenet-2018-105709. [Epub ahead of print].

Granulin 1 Promotes Retinal Regeneration in Zebrafish

Authors:
Tsuruma K, Saito Y, Okuyoshi H, Yamaguchi A, Shimazawa M, Goldman D, Hara H
Citation:
Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6057-6066. doi: 10.1167/iovs.18-24828
Epub:
Not Epub
Abstract:
Purpose: Retinal degenerative diseases can progress to severe reductions of vision. In general, the changes are permanent in...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Tsuruma K, Saito Y, Okuyoshi H, Yamaguchi A, Shimazawa M, Goldman D, Hara H. Granulin 1 Promotes Retinal Regeneration in Zebrafish. Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6057-6066. doi: 10.1167/iovs.18-24828.

Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio)

Authors:
Eisa-Beygi S, Benslimane FM, El-Rass S, Prabhudesai S, Abdelrasoul MKA, Simpson PM, Yalcin HC, Burrows PE, Ramchandran R
Citation:
Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2806-2818. doi: 10.1161/ATVBAHA.118.311231
Epub:
Not Epub
Abstract:
Objective- Endothelial cells (ECs) sense and respond to flow-induced mechanical stress, in part, via microtubule-based...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eisa-Beygi S, Benslimane FM, El-Rass S, Prabhudesai S, Abdelrasoul MKA, Simpson PM, Yalcin HC, Burrows PE, Ramchandran R. Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio). Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2806-2818. doi: 10.1161/ATVBAHA.118.311231.

Endodermal pouch-expressed dmrt2b is important for pharyngeal cartilage formation

Authors:
Li L, Mao A, Wang P, Ning G, Cao Y, Wang Q
Citation:
Biol Open. 2018 Dec 17;7(12). pii: bio035444. doi: 10.1242/bio.035444
Epub:
Not Epub
Abstract:
Pharyngeal pouches, a series of outpocketings derived from the foregut endoderm, are essential for craniofacial skeleton...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Mao A, Wang P, Ning G, Cao Y, Wang Q. Endodermal pouch-expressed dmrt2b is important for pharyngeal cartilage formation. Biol Open. 2018 Dec 17;7(12). pii: bio035444. doi: 10.1242/bio.035444.

Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos

Authors:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E
Citation:
Nat Commun. 2018 Dec 14;9(1):5314. doi: 10.1038/s41467-018-07732-7
Epub:
Not Epub
Abstract:
Arteries and veins are formed independently by different types of endothelial cells (ECs). In vascular remodeling, arteries and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. Nat Commun. 2018 Dec 14;9(1):5314. doi: 10.1038/s41467-018-07732-7.

Hif-1α-Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish

Authors:
Ogryzko NV, Lewis A, Wilson HL, Meijer AH, Renshaw SA, Elks PM
Citation:
J Immunol. 2018 Dec 14. pii: ji1801139. doi: 10.4049/jimmunol.1801139. [Epub ahead of print]
Epub:
Yes
Abstract:
Drug-resistant mycobacteria are a rising problem worldwide. There is an urgent need to understand the immune response to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ogryzko NV, Lewis A, Wilson HL, Meijer AH, Renshaw SA, Elks PM. Hif-1α-Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish. J Immunol. 2018 Dec 14. pii: ji1801139. doi: 10.4049/jimmunol.1801139. [Epub ahead of print].

Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy

Authors:
Corbett MA, van Eyk CL, Webber DL, Bent SJ, Newman M, Kelly Harper, Berry JG, Azmanov DN, Woodward KJ, Gardner AE, Slee J, Pérez-Jurado LA, MacLennan AH, Gecz J
Citation:
npj Genomic Med. 2018;3:33 doi:10.1038/s41525-018-0073-4
Epub:
Not Epub
Abstract:
Cerebral palsy (CP) is the most frequent movement disorder of childhood affecting 1 in 500 live births in developed countries....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Corbett MA, van Eyk CL, Webber DL, Bent SJ, Newman M, Kelly Harper, Berry JG, Azmanov DN, Woodward KJ, Gardner AE, Slee J, Pérez-Jurado LA, MacLennan AH, Gecz J. Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy. npj Genomic Med. 2018;3:33 doi:10.1038/s41525-018-0073-4.

Alteration of the Retinoid Acid-CBP Signaling Pathway in Neural Crest Induction Contributes to Enteric Nervous System Disorder

Authors:
Li C, Hu R, Hou N, Wang Y, Wang Z, Yang T, Gu Y, He M, Shi Y, Chen J, Song W, Li T
Citation:
Front Pediatr. 2018 Dec 3;6:382. doi: 10.3389/fped.2018.00382. eCollection 2018
Epub:
Not Epub
Abstract:
Hirschsprung Disease (HSCR) and/or hypoganglionosis are common pediatric disorders that arise from developmental deficiencies...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li C, Hu R, Hou N, Wang Y, Wang Z, Yang T, Gu Y, He M, Shi Y, Chen J, Song W, Li T. Alteration of the Retinoid Acid-CBP Signaling Pathway in Neural Crest Induction Contributes to Enteric Nervous System Disorder. Front Pediatr. 2018 Dec 3;6:382. doi: 10.3389/fped.2018.00382. eCollection 2018.

Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis

Authors:
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY
Citation:
Nat Commun. 2018 Dec 11;9(1):5277. doi: 10.1038/s41467-018-07664-2
Epub:
Not Epub
Abstract:
Defective ciliogenesis causes human developmental diseases termed ciliopathies. Microtubule (MT) asters originating from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY. Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis. Nat Commun. 2018 Dec 11;9(1):5277. doi: 10.1038/s41467-018-07664-2.

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