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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Inhibiting neutral amino acid transport for the treatment of phenylketonuria
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Citation:
JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. [Epub ahead of print] Epub:
Not Epub Abstract:
The neuropathological effects of phenylketonuria (PKU) stem from the inability of the body to metabolize excess phenylalanine (... Delivery Method:
Endo-Porter in culture, peptide-linked in mice Organism or Cell Type:
cell culture: primary mouse renal tubular epithelial cells, mice Citation Extract: Belanger AM, Przybylska M, Gefteas E, Furgerson M, Geller S, Kloss A, Cheng SH, Zhu Y, Yew NS. Inhibiting neutral amino acid transport for the treatment of phenylketonuria. JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. [Epub ahead of print]. |
Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking
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Citation:
JCI Insight. 2018 Jul 26;3(14). pii: 121596. doi: 10.1172/jci.insight.121596. [Epub ahead of print] Epub:
Not Epub Abstract:
Site-1 protease (S1P), encoded by MBTPS1, is a serine protease in the Golgi. S1P regulates lipogenesis, endoplasmic reticulum (... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human primary fibroblasts, immortalized Citation Extract: Kondo Y, Fu J, Wang H, Hoover C, McDaniel JM, Steet R, Patra D, Song J, Pollard L, Cathey S, Yago T, Wiley G, Macwana S, Guthridge J, McGee S, Li S, Griffin C, Furukawa K, James JA, Ruan C, McEver RP, Wierenga KJ, Gaffney PM, Xia L. Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking. JCI Insight. 2018 Jul 26;3(14). pii: 121596. doi: 10.1172/jci.insight.121596. [Epub ahead of print]. |
Long non-coding RNAs are largely dispensable for zebrafish embryogenesis, viability and fertility
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Citation:
bioRXive. 2018;[Epub] doi:10.1101/374702 Epub:
Yes Abstract:
Hundreds of long non-coding RNAs (lncRNAs) have been identified as potential regulators of gene expression, but their functions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mehdi Goudarzi, Kathryn Berg, Lindsey M Pieper, Alexander F Schier. Long non-coding RNAs are largely dispensable for zebrafish embryogenesis, viability and fertility. bioRXive. 2018;[Epub] doi:10.1101/374702. |
Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner
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Citation:
Elife. 2018 Jul 23;7. pii: e34404. doi: 10.7554/eLife.34404 Epub:
Not Epub Abstract:
Neural crest progenitors are specified through the modulation of several signaling pathways, among which the activation of Wnt/... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Devotta A, Hong CS, Saint-Jeannet JP. Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner. Elife. 2018 Jul 23;7. pii: e34404. doi: 10.7554/eLife.34404. |
Positive-feedback defines the timing and robustness of angiogenesis
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Citation:
bioRXive. 2018;[Epub] doi:10.1101/374389 Epub:
Not Epub Abstract:
Blood vessel formation by angiogenesis is critical for tissue development, homeostasis and repair, and is frequently... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Page DJ, Thuret R, Venkatraman L, Takahashi T, Bentley K, Herbert SP. Positive-feedback defines the timing and robustness of angiogenesis. bioRXive. 2018;[Epub] doi:10.1101/374389. |
A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis
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Citation:
BMC Biol. 2018 Jul 16;16(1):79. doi: 10.1186/s12915-018-0540-5 Epub:
Not Epub Abstract:
BACKGROUND: The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Maharana SK, Schlosser G. A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis. BMC Biol. 2018 Jul 16;16(1):79. doi: 10.1186/s12915-018-0540-5. |
Elesclomol restores mitochondrial function in genetic models of copper deficiency
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Citation:
Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23 Epub:
Not Epub Abstract:
Copper is an essential cofactor of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Soma S, Latimer AJ, Chun H, Vicary AC, Timbalia SA, Boulet A, Rahn JJ, Chan SSL, Leary SC, Kim BE, Gitlin JD, Gohil VM. Elesclomol restores mitochondrial function in genetic models of copper deficiency. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23. |
The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis
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Citation:
Dev Biol. 2014 May 15;389(2):182-91. doi: 10.1016/j.ydbio.2014.02.014. Epub 2014 Mar 7 Epub:
Not Epub Abstract:
The vertebrate heart undergoes early complex morphologic events in order to develop key cardiac structures that regulate its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC. The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dev Biol. 2014 May 15;389(2):182-91. doi: 10.1016/j.ydbio.2014.02.014. Epub 2014 Mar 7. |
Cerebral Cavernous Malformation 1/2 complex controls ROCK1 and ROCK2 complementary functions for endothelial integrity
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Citation:
J Cell Sci. 2018;[Epub] doi:10.1242/jcs.216093 Epub:
Yes Abstract:
Endothelial integrity relies on a mechanical crosstalk between intercellular and cell-matrix interactions. This cross-talk is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lisowska J, Rödel CJ, Manet S, Miroshnikova YA, Boyault C, Planus E, De Mets R, Lee H-H, Destaing O, Mertani H, Boulday G, Tournier-Lasserve E, Balland M, Abdelilah-Seyfried S, Albiges-Rizo C, Faurobert E. . Cerebral Cavernous Malformation 1/2 complex controls ROCK1 and ROCK2 complementary functions for endothelial integrity. J Cell Sci. 2018;[Epub] doi:10.1242/jcs.216093. |
Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma
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Citation:
Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7351-E7360. doi: 10.1073/pnas.1800039115. Epub 2018 Jul 18 Epub:
Not Epub Abstract:
Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system in which MycN amplification is a... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Kerosuo L, Neppala P, Hsin J, Mohlin S, Vieceli FM, Török Z, Laine A, Westermarck J, Bronner ME. Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7351-E7360. doi: 10.1073/pnas.1800039115. Epub 2018 Jul 18. |