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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting

Authors:
Sturtzel C, Lipnik K, Hofer-Warbinek R, Testori J, Ebner B, Seigner J, Qiu P, Bilban M, Jandrositz A, Preisegger KH, Untergasser G, Gunsilius E, de Martin R, Kroll J, Hofer E
Citation:
Front Bioeng Biotechnol. 2018 Jun 14;6:76. doi: 10.3389/fbioe.2018.00076. eCollection 2018
Epub:
Not Epub
Abstract:
Endothelial colony forming cells (ECFC) or late blood outgrowth endothelial cells (BOEC) have been proposed to contribute to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sturtzel C, Lipnik K, Hofer-Warbinek R, Testori J, Ebner B, Seigner J, Qiu P, Bilban M, Jandrositz A, Preisegger KH, Untergasser G, Gunsilius E, de Martin R, Kroll J, Hofer E. FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting. Front Bioeng Biotechnol. 2018 Jun 14;6:76. doi: 10.3389/fbioe.2018.00076. eCollection 2018.

Prion gene paralogs are dispensable for early zebrafish development but have non-additive roles in seizure susceptibility

Authors:
Leighton PLA, Kanyo R, Neil GJ, Pollock NM, Allison WT
Citation:
J Biol Chem. 2018 Jun 14. pii: jbc.RA117.001171. doi: 10.1074/jbc.RA117.001171. [Epub ahead of print]
Epub:
Yes
Abstract:
Normally folded prion protein (PrPC) and its functions in healthy brains remain underappreciated compared to the intense study...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leighton PLA, Kanyo R, Neil GJ, Pollock NM, Allison WT. Prion gene paralogs are dispensable for early zebrafish development but have non-additive roles in seizure susceptibility. J Biol Chem. 2018 Jun 14. pii: jbc.RA117.001171. doi: 10.1074/jbc.RA117.001171. [Epub ahead of print].

Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat

Authors:
Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, Yan X, Zhu X
Citation:
J Mol Cell Biol. 2018 Jul 28. doi: 10.1093/jmcb/mjy043. [Epub ahead of print]
Epub:
Yes
Abstract:
Motile cilia and flagella are microtubule-based organelles important for cell locomotion and extracellular liquid flow through...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, Yan X, Zhu X. Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. J Mol Cell Biol. 2018 Jul 28. doi: 10.1093/jmcb/mjy043. [Epub ahead of print].

Developmental mechanisms of migratory muscle precursors in medaka pectoral fin formation

Authors:
Tani-Matsuhana S, Kusakabe R, Inoue K
Citation:
Dev Genes Evol. 2018 Jul 14. doi: 10.1007/s00427-018-0616-9. [Epub ahead of print]
Epub:
Yes
Abstract:
Limb muscles are formed from migratory muscle precursor cells (MMPs) that delaminate from the ventral region of dermomyotomes...
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Tani-Matsuhana S, Kusakabe R, Inoue K. Developmental mechanisms of migratory muscle precursors in medaka pectoral fin formation. Dev Genes Evol. 2018 Jul 14. doi: 10.1007/s00427-018-0616-9. [Epub ahead of print].

Geminin Orchestrates Somite Formation by Regulating Fgf8 and Notch Signaling

Authors:
Huang W, Zhang Y, Cao K, Luo L, Huang S
Citation:
Biomed Res Int. 2018 Jun 7;2018:6543196. doi: 10.1155/2018/6543196. eCollection 2018
Epub:
Not Epub
Abstract:
During somitogenesis, Fgf8 maintains the predifferentiation stage of presomitic mesoderm (PSM) cells and its retraction gives a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang W, Zhang Y, Cao K, Luo L, Huang S. Geminin Orchestrates Somite Formation by Regulating Fgf8 and Notch Signaling. Biomed Res Int. 2018 Jun 7;2018:6543196. doi: 10.1155/2018/6543196. eCollection 2018.

Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish

Authors:
Yang D, Zheng X, Chen S, Wang Z, Xu W, Tan J, Hu T, Hou M, Wang W, Gu Z, Wang Q, Zhang R, Zhang Y, Liu Q
Citation:
Nat Commun. 2018 Aug 3;9(1):3052. doi: 10.1038/s41467-018-04984-1
Epub:
Not Epub
Abstract:
The noncanonical inflammasome is critical for cytosolic sensing of Gram-negative pathogens. Here, we show that bacterial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang D, Zheng X, Chen S, Wang Z, Xu W, Tan J, Hu T, Hou M, Wang W, Gu Z, Wang Q, Zhang R, Zhang Y, Liu Q. Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish. Nat Commun. 2018 Aug 3;9(1):3052. doi: 10.1038/s41467-018-04984-1.

Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction

Authors:
Piacentino ML, Bronner ME
Citation:
PLoS Biol. 2018 Jun 27;16(6):e2004425. doi: 10.1371/journal.pbio.2004425. eCollection 2018 Jun
Epub:
Not Epub
Abstract:
The neural crest is induced at the neural plate border during gastrulation by combined bone morphogenetic protein (BMP),...
Delivery Method:
injection and electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Piacentino ML, Bronner ME. Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction. PLoS Biol. 2018 Jun 27;16(6):e2004425. doi: 10.1371/journal.pbio.2004425. eCollection 2018 Jun.

Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model

Authors:
Ma JX, Li JY, Fan DD, Feng W, Lin AF, Xiang LX, Shao JZ
Citation:
Front Immunol. 2018 Jun 11;9:1327. doi: 10.3389/fimmu.2018.01327. eCollection 2018
Epub:
Not Epub
Abstract:
DDX41 is an important sensor for host recognition of DNA viruses and initiation of nuclear factor-κB (NF-κB) and IFN signaling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma JX, Li JY, Fan DD, Feng W, Lin AF, Xiang LX, Shao JZ. Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model. Front Immunol. 2018 Jun 11;9:1327. doi: 10.3389/fimmu.2018.01327. eCollection 2018.

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels

Authors:
Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkey D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ
Citation:
Nat Commun. 2018 Jun 13;9(1):2302. doi: 10.1038/s41467-018-04586-x
Epub:
Not Epub
Abstract:
PKD2 and PKD1 genes are mutated in human autosomal dominant polycystic kidney disease. PKD2 can form either a homomeric cation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkey D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ. Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun. 2018 Jun 13;9(1):2302. doi: 10.1038/s41467-018-04586-x.

Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes

Authors:
Chiquet BT, Yuan Q, Swindell EC, Maili L, Plant R, Dyke J, Boyer R, Teichgraeber JF, Greives MR, Mulliken JB, Letra A, Blanton SH, Hecht JT
Citation:
Eur J Hum Genet. 2018 Jun 13. doi: 10.1038/s41431-018-0192-5. [Epub ahead of print]
Epub:
Yes
Abstract:
Orofacial development is a multifaceted process involving tightly regulated genetic signaling networks, that when perturbed,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiquet BT, Yuan Q, Swindell EC, Maili L, Plant R, Dyke J, Boyer R, Teichgraeber JF, Greives MR, Mulliken JB, Letra A, Blanton SH, Hecht JT. Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes. Eur J Hum Genet. 2018 Jun 13. doi: 10.1038/s41431-018-0192-5. [Epub ahead of print].

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