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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

Authors:
Svahn AJ, Don EK, Badrock AP, Cole NJ, Graeber MB, Yerbury JJ, Chung R, Morsch M
Citation:
Acta Neuropathol. 2018 Jun 25. doi: 10.1007/s00401-018-1875-2. [Epub ahead of print]
Epub:
Yes
Abstract:
Transactivating DNA-binding protein-43 (TDP-43) deposits represent a typical finding in almost all ALS patients, more than half...
Link:
https://link.springer.com/article/10.1007%2Fs00401-018-1875-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Svahn AJ, Don EK, Badrock AP, Cole NJ, Graeber MB, Yerbury JJ, Chung R, Morsch M. Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons. Acta Neuropathol. 2018 Jun 25. doi: 10.1007/s00401-018-1875-2. [Epub ahead of print].

Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection

Authors:
Willis AR, Torraca V, Gomes MC, Shelley J, Mazon-Moya M, Filloux A, Lo Celso C, Mostowy S
Citation:
MBio. 2018 Jun 26;9(3). pii: e00933-18. doi: 10.1128/mBio.00933-18
Epub:
Not Epub
Abstract:
Emergency granulopoiesis is a hematopoietic program of stem cell-driven neutrophil production used to counteract immune cell...
Link:
http://mbio.asm.org/content/9/3/e00933-18.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willis AR, Torraca V, Gomes MC, Shelley J, Mazon-Moya M, Filloux A, Lo Celso C, Mostowy S. Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection. MBio. 2018 Jun 26;9(3). pii: e00933-18. doi: 10.1128/mBio.00933-18.

Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration

Authors:
Boutry M, Branchu J, Lustremant C, Pujol C, Pernelle J, Matusiak R, Seyer A, Poirel M, Chu-Van E, Pierga A, Dobrenis K, Puech JP, Caillaud C, Durr A, Brice A, Colsch B, Mochel F, El Hachimi KH, Stevanin G, Darios F
Citation:
Cell Rep. 2018 Jun 26;23(13):3813-3826. doi: 10.1016/j.celrep.2018.05.098
Epub:
Not Epub
Abstract:
Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30894-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boutry M, Branchu J, Lustremant C, Pujol C, Pernelle J, Matusiak R, Seyer A, Poirel M, Chu-Van E, Pierga A, Dobrenis K, Puech JP, Caillaud C, Durr A, Brice A, Colsch B, Mochel F, El Hachimi KH, Stevanin G, Darios F. Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration. Cell Rep. 2018 Jun 26;23(13):3813-3826. doi: 10.1016/j.celrep.2018.05.098.

A novel mechanism of gland formation in zebrafish involving transdifferentiation of renal epithelial cells and live cell extrusion

Authors:
Naylor RW, Davidson AJ
Citation:
bioRXive. 2018;[Epub] doi:doi.org/10.1101/353524
Epub:
Yes
Abstract:
Transdifferentiation is the poorly understood phenomenon whereby a terminally differentiated cell acquires a completely new...
Link:
https://www.biorxiv.org/content/early/2018/06/22/353524
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Naylor RW, Davidson AJ . A novel mechanism of gland formation in zebrafish involving transdifferentiation of renal epithelial cells and live cell extrusion. bioRXive. 2018;[Epub] doi:doi.org/10.1101/353524 .

Nucleoporin 133 deficiency leads to glomerular damage in zebrafish

Authors:
Cosentino CC, Berto A, Hari M, Loffing J, Neuhauss SCF, Doye V
Citation:
bioRXive. 2018;[Epub] doi:10.1101/352971
Epub:
Yes
Abstract:
Although structural nuclear pore proteins (nucleoporins) are seemingly required in every cell type to assemble a functional...
Link:
https://www.biorxiv.org/content/early/2018/06/21/352971
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cosentino CC, Berto A, Hari M, Loffing J, Neuhauss SCF, Doye V. Nucleoporin 133 deficiency leads to glomerular damage in zebrafish. bioRXive. 2018;[Epub] doi:10.1101/352971.

Use of chick neural tube for optimizing the PSM and epithelial somites electroporation parameters: A detailed protocol

Authors:
Abu-Elmagd M
Citation:
J Biol Methods 2018;5(2):e93. doi: 10.14440/jbm.2018.253
Epub:
Not Epub
Abstract:
Somite myogenesis is one of the crucial early embryonic events that lead to the formation of muscular tissue. A complex of...
Link:
http://www.jbmethods.org/jbm/article/view/253/212
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Abu-Elmagd M. Use of chick neural tube for optimizing the PSM and epithelial somites electroporation parameters: A detailed protocol. J Biol Methods 2018;5(2):e93. doi: 10.14440/jbm.2018.253.

CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons

Authors:
Liu ZZ, Zhu J, Wang CL, Wang X, Han YY, Liu LY, Xu HA
Citation:
Neural Plast. 2018 Jun 21;2018:8791304. doi: 10.1155/2018/8791304. eCollection 2018
Epub:
Not Epub
Abstract:
Axons are directed to their correct targets by guidance cues during neurodevelopment. Many axon guidance cues have been...
Link:
https://www.hindawi.com/journals/np/2018/8791304/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ZZ, Zhu J, Wang CL, Wang X, Han YY, Liu LY, Xu HA. CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons. Neural Plast. 2018 Jun 21;2018:8791304. doi: 10.1155/2018/8791304. eCollection 2018.

Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

Authors:
Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstädter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler M-C, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, Kuehn EW
Citation:
EMBO J. 2018;[Epub ahead of print] doi:10.15252/embj.201798615
Epub:
Yes
Abstract:
Polycystic kidney disease (PKD) and other renal ciliopathies are characterized by cysts, inflammation, and fibrosis. Cilia...
Link:
http://emboj.embopress.org/content/37/15/e98615.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstädter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler M-C, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, Kuehn EW. Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;[Epub ahead of print] doi:10.15252/embj.201798615.

Functional characterisation of romeharsha and clint1 reaffirms the link between plasma membrane homeostasis, cell size maintenance and tissue homeostasis in developing zebrafish epidermis

Authors:
Phatak M, Sonawane M
Citation:
J Biosci. 2018 Sep;43(4):605-619.
Epub:
Yes
Abstract:
In vertebrates, early developing epidermis is a bilayered epithelium consisting of an outer periderm and the underlying basal...
Link:
https://www.ias.ac.in/describe/article/jbsc/043/04/0605-0619
Organism or Cell Type:
zebrafish
Citation Extract:
Phatak M, Sonawane M. Functional characterisation of romeharsha and clint1 reaffirms the link between plasma membrane homeostasis, cell size maintenance and tissue homeostasis in developing zebrafish epidermis. J Biosci. 2018 Sep;43(4):605-619..

Size control of the inner ear via hydraulic feedback

Authors:
Mosaliganti KR, Swinburne IA, Chan CU, Obholzer ND, Green AA, Tanksale S, Mahadevan L, Megason SG
Citation:
bioRXive. 2018. doi:10.1101/349381
Epub:
Yes
Abstract:
Animals make organs of precise size, shape, and symmetry despite noise in underlying molecular and cellular processes. How...
Link:
https://www.biorxiv.org/content/early/2018/06/19/349381
Organism or Cell Type:
zebrafish
Citation Extract:
Mosaliganti KR, Swinburne IA, Chan CU, Obholzer ND, Green AA, Tanksale S, Mahadevan L, Megason SG. Size control of the inner ear via hydraulic feedback. bioRXive. 2018. doi:10.1101/349381.

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