You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development

Authors:
Kesner P, Schohl A, Warren EC, Fan Ma F, Ruthazer ES
Citation:
Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955
Epub:
Not Epub
Abstract:
To study contributions of N-methyl-D-aspartate receptors (NMDARs) in presynaptic and postsynaptic neurons of the developing...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30936-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kesner P, Schohl A, Warren EC, Fan Ma F, Ruthazer ES. Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development. Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955.

Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis

Authors:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N
Citation:
bioRxiv 20205;[preprint] doi:10.1101/2020.07.26.221515
Epub:
Not Epub
Abstract:
Animal cytokinesis ends with the formation of a thin intercellular membrane bridge connecting the two newly formed sibling...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.26.221515v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N. Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis. bioRxiv 20205;[preprint] doi:10.1101/2020.07.26.221515.

Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1B/BUBR1 Signaling

Authors:
Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.07.24.220475
Epub:
Not Epub
Abstract:
Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure, and/or spontaneous...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.24.220475v1
Delivery Method:
microinjection
Organism or Cell Type:
Bos taurus (cattle) oocytes
Citation Extract:
Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL. Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1B/BUBR1 Signaling. bioRxiv 2020;[preprint] doi:10.1101/2020.07.24.220475 .

MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B

Authors:
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C
Citation:
EMBO J. 2020 Jul 27:e105696. doi: 10.15252/embj.2020105696. Online ahead of print
Epub:
Yes
Abstract:
Lysosomal degradation of the endoplasmic reticulum (ER) via autophagy (ER-phagy) is emerging as a critical regulator of cell...
Link:
https://www.embopress.org/doi/epdf/10.15252/embj.2020105696
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C. MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. EMBO J. 2020 Jul 27:e105696. doi: 10.15252/embj.2020105696. Online ahead of print.

Heroin Cues Reveal Astroglial Heterogeneity in the Nucleus Accumbens Core

Authors:
Kruyer A, Kalivas PW
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.22.216036
Epub:
Not Epub
Abstract:
BACKGROUND: Cues predicting heroin delivery induce heroin seeking by initiating synaptic glutamate release in the nucleus...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.22.216036v1
Delivery Method:
brain infusion
Organism or Cell Type:
Rattus norvegicus (Rat) Sprague-Dawley
Citation Extract:
Kruyer A, Kalivas PW. Heroin Cues Reveal Astroglial Heterogeneity in the Nucleus Accumbens Core. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.22.216036 .

The effect of absent blood flow on the zebrafish cerebral and trunk vasculature

Authors:
Kugler E, Snodgrass R, Bowley G, Plant K, Serbanovic-Canic J, Evans PC, Chico T, Armitage P
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.23.216192
Epub:
Not Epub
Abstract:
The role of blood flow is complex and context-dependent. In this study, we quantify the effect of the lack of blood flow on...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.23.216192v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kugler E, Snodgrass R, Bowley G, Plant K, Serbanovic-Canic J, Evans PC, Chico T, Armitage P. The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.23.216192 .

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development

Authors:
Da’as SI, Aamer W, Hasan W, Al-Maraghi A, Al-Kurbi A, Kilani H, AlRayahi J, Zamel K, Stotland MA, Fakhro KA
Citation:
Cells. 2020;9(8):2073-4409. doi:10.3390/cells9081782
Epub:
Not Epub
Abstract:
Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with...
Link:
https://www.mdpi.com/2073-4409/9/8/1782/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Da’as SI, Aamer W, Hasan W, Al-Maraghi A, Al-Kurbi A, Kilani H, AlRayahi J, Zamel K, Stotland MA, Fakhro KA. PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development. Cells. 2020;9(8):2073-4409. doi:10.3390/cells9081782.

RNA-Seq analysis on ets1 mutant embryos of Xenopus tropicalis identifies microseminoprotein beta gene 3 as an essential regulator of neural crest migration

Authors:
Wang C, Qi X, Zhou X, Sun J, Cai D, Lu G, Chen X, Jiang Z, Yao YG, Chan WY, Zhao H
Citation:
FASEB J. 2020 Jul 26. doi: 10.1096/fj.202000603R. Online ahead of print
Epub:
Yes
Abstract:
The proto-oncogene ets1 is highly expressed in the pre-migratory and migratory neural crest (NC), and has been implicated in...
Link:
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202000603R
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis & Xenopus tropicalis
Citation Extract:
Wang C, Qi X, Zhou X, Sun J, Cai D, Lu G, Chen X, Jiang Z, Yao YG, Chan WY, Zhao H. RNA-Seq analysis on ets1 mutant embryos of Xenopus tropicalis identifies microseminoprotein beta gene 3 as an essential regulator of neural crest migration. FASEB J. 2020 Jul 26. doi: 10.1096/fj.202000603R. Online ahead of print.

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

Authors:
Bestle D, Heindl MR, Limburg H, Lam van TV, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk H-D, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E
Citation:
Life Sci Alliance. 2020;3(9):e202000786 doi:10.26508/lsa.202000786
Epub:
Not Epub
Abstract:
The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute infection of the respiratory tract (COVID-19)...
Link:
https://www.life-science-alliance.org/content/3/9/e202000786
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: Calu-3 human airway epithelial cells
Citation Extract:
Bestle D, Heindl MR, Limburg H, Lam van TV, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk H-D, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells. Life Sci Alliance. 2020;3(9):e202000786 doi:10.26508/lsa.202000786.

Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio)

Authors:
Parker JJ, Zimmer AM, Perry SF
Citation:
J Exp Biol. 2020;jeb.226753 [Epub ahead of print] doi:10.1242/jeb.226753
Epub:
Yes
Abstract:
Fishes living in fresh water counter the passive loss of salts by actively absorbing ions through specialized cells termed...
Link:
https://jeb.biologists.org/content/early/2020/07/23/jeb.226753
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Parker JJ, Zimmer AM, Perry SF. Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio). J Exp Biol. 2020;jeb.226753 [Epub ahead of print] doi:10.1242/jeb.226753.

Pages