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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model

Authors:
Johansen MD, Kremer L
Citation:
Front Cell Infect Microbiol. 2020;10:357. doi:10.3389/fcimb.2020.00357
Epub:
Not Epub
Abstract:
The Mycobacterium fortuitum complex comprises several closely related species, causing pulmonary and extra-pulmonary infections...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansen MD, Kremer L. CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model. Front Cell Infect Microbiol. 2020;10:357. doi:10.3389/fcimb.2020.00357.

Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide

Authors:
Nikan M, Tanowitz M, Dwyer CA, Jackson M, Gaus H, Swayze E, Rigo F, Seth PP, Prakash TP
Citation:
J Med Chem. 2020 Jul 17. doi:10.1021/acs.jmedchem.0c00840. Online ahead of print
Epub:
Not Epub
Abstract:
Despite recent advances, targeted delivery of therapeutic oligonucleotide to extra-hepatic tissues continues to be a...
Delivery Method:
peptide-linked, intracerebroventricular (i.c.v.) injection in mice
Organism or Cell Type:
cell culture: HEK293, mice
Citation Extract:
Nikan M, Tanowitz M, Dwyer CA, Jackson M, Gaus H, Swayze E, Rigo F, Seth PP, Prakash TP. Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide. J Med Chem. 2020 Jul 17. doi:10.1021/acs.jmedchem.0c00840. Online ahead of print.

Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Goerne J, Wallingford JB, Hammes-Lewin A, Feistel K

Authors:
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.15.205252
Epub:
Not Epub
Abstract:
Recent studies have revealed that pathogenic mutations in the endocytic receptor LRP2 in humans are associated with severe...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds. Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Goerne J, Wallingford JB, Hammes-Lewin A, Feistel K. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.15.205252 .

VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii

Authors:
Li J, Liu H, Ma Q, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Guan H, Liu X, Li Q, Han Y
Citation:
Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.07.013
Epub:
Yes
Abstract:
The complement component 3 of the lamprey, a jawless vertebrate, functions as an opsonin during the phagocytosis of rabbit red...
Delivery Method:
microinjection
Organism or Cell Type:
Lampetra morii (lamprey)
Citation Extract:
Li J, Liu H, Ma Q, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Guan H, Liu X, Li Q, Han Y. VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii. Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.07.013.

Wang X, Dunlap K, Satterfield M, Frank J, Li X, Ying W, Burghardt R, Johnson GA, Wu G, Antoniazzi AQ, Nett TM, Hansen TR, Bazer FW

Authors:
Effects of In Vivo Knockdown of Translation of Arginine-Associated Gene Transcripts in Conceptus Trophectoderm on Growth, Development, and Gene Expression by Ovine Conceptuses
Citation:
Biol Reprod. 2012;87(suppl 1)394. doi:10.1093/biolreprod/87.s1.394
Epub:
Not Epub
Abstract:
Arginine (Arg), a nutritionally essential amino acid for conceptus development, can be metabolized to nitric oxide (NO) and...
Delivery Method:
bathing in uterine lumen
Organism or Cell Type:
Ovis aries (sheep) conceptus
Citation Extract:
Effects of In Vivo Knockdown of Translation of Arginine-Associated Gene Transcripts in Conceptus Trophectoderm on Growth, Development, and Gene Expression by Ovine Conceptuses . Wang X, Dunlap K, Satterfield M, Frank J, Li X, Ying W, Burghardt R, Johnson GA, Wu G, Antoniazzi AQ, Nett TM, Hansen TR, Bazer FW. Biol Reprod. 2012;87(suppl 1)394. doi:10.1093/biolreprod/87.s1.394.

Sensory Neuroblast Quiescence Dependson Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow

Authors:
Taberner L, Banñó A, Alsina B
Citation:
Cell Rep. 2020;32:107903. doi:10.1016/j.celrep.2020.107903
Epub:
Not Epub
Abstract:
In many organs, stem cell function depends on communication with their niche partners. Cranial sensory neurons develop in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taberner L, Banñó A, Alsina B. Sensory Neuroblast Quiescence Dependson Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow. Cell Rep. 2020;32:107903. doi:10.1016/j.celrep.2020.107903.

IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules

Authors:
Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A
Citation:
Nat Commun. 2020;11(1):3516 doi:10.1038/s41467-020-17091-x
Epub:
Not Epub
Abstract:
It is unclear whether the establishment of apical–basal cell polarity during the generation of epithelial lumens requires...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A. IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules. Nat Commun. 2020;11(1):3516 doi:10.1038/s41467-020-17091-x.

Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis

Authors:
Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried SA
Citation:
Cell Rep. 2020;32(2):107833. doi:10.1016/j.celrep.2020.107883
Epub:
Not Epub
Abstract:
The formation of cardiac valves depends on mechanical forces exerted by blood flow. Endocardial cells lining the interior of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried SA. Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis. Cell Rep. 2020;32(2):107833. doi:10.1016/j.celrep.2020.107883.

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation

Authors:
Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, Busch-Nentwich EM, Zon LI, Illingworth RS, Patton EE
Citation:
Dev Cell. 2020 Jul 8:S1534-5807(20)30463-9. doi: 10.1016/j.devcel.2020.06.013. Online ahead of print
Epub:
Yes
Abstract:
Melanocytes, replenished throughout life by melanocyte stem cells (MSCs), play a critical role in pigmentation and melanoma....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, Busch-Nentwich EM, Zon LI, Illingworth RS, Patton EE. PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation. Dev Cell. 2020 Jul 8:S1534-5807(20)30463-9. doi: 10.1016/j.devcel.2020.06.013. Online ahead of print.

Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia

Authors:
Gauert A, Olk N, Pimentel-Gutiérrez H, Astrahantseff K, Jensen LD, Cao Yihai, Eggert A, Eckert C, Hagemann AIH
Citation:
Cancers. 2020;12(7):[Epub] doi:10.3390/cancers12071883
Epub:
Not Epub
Abstract:
Only half of patients with relapsed B-cell precursor (BCP) acute lymphoblastic leukemia (ALL) currently survive with standard...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gauert A, Olk N, Pimentel-Gutiérrez H, Astrahantseff K, Jensen LD, Cao Yihai, Eggert A, Eckert C, Hagemann AIH. Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia. Cancers. 2020;12(7):[Epub] doi:10.3390/cancers12071883.

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