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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Studies in zebrafish demonstrate that CNNM2 and NT5C2 are most likely the causal genes at the blood pressure-associated locus on human chromosome 10q24.32

Authors:
Vishnolia KK, Hoene C, Tarhbalouti K, Revenstorff J, Aherrahrou Z, Erdmann J
Citation:
Front Cardiovasc Med. 2020 Sep 2;7:135. doi: 10.3389/fcvm.2020.00135
Epub:
Not Epub
Abstract:
Background: Globally, high blood pressure (BP) is the most important risk factor for cardiovascular disease. Several genome-...
Organism or Cell Type:
zebrafish
Citation Extract:
Vishnolia KK, Hoene C, Tarhbalouti K, Revenstorff J, Aherrahrou Z, Erdmann J. Studies in zebrafish demonstrate that CNNM2 and NT5C2 are most likely the causal genes at the blood pressure-associated locus on human chromosome 10q24.32. Front Cardiovasc Med. 2020 Sep 2;7:135. doi: 10.3389/fcvm.2020.00135.

Ets1 functions partially redundantly with Etv2 to promote embryonic vasculogenesis and angiogenesis in zebrafish

Authors:
Chetty SC, Sumanas S
Citation:
Dev Biol. 2020;[Epub ahead of print] doi:10.1016/j.ydbio.2020.06.007
Epub:
Yes
Abstract:
ETS transcription factors play an important role in the specification and differentiation of endothelial cells during vascular...
Organism or Cell Type:
zebrafish
Citation Extract:
Chetty SC, Sumanas S. Ets1 functions partially redundantly with Etv2 to promote embryonic vasculogenesis and angiogenesis in zebrafish. Dev Biol. 2020;[Epub ahead of print] doi:10.1016/j.ydbio.2020.06.007.

Premature termination codons in the DMD gene cause reduced local mRNA synthesis

Authors:
García-Rodríguez R, Hiller M, Jiménez-Gracia L, van der Pal Z, Balog J, Adamzek K, Aartsma-Rus A, Spitali P
Citation:
Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.1910456117
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene leading to the presence of premature termination...
Delivery Method:
injection
Organism or Cell Type:
mice mdx
Citation Extract:
García-Rodríguez R, Hiller M, Jiménez-Gracia L, van der Pal Z, Balog J, Adamzek K, Aartsma-Rus A, Spitali P . Premature termination codons in the DMD gene cause reduced local mRNA synthesis. Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.1910456117.

Microglia phagocytose myelin sheaths to modify developmental myelination

Authors:
Hughes AN, Appel B
Citation:
Nat Neurosci. 2020;[Epub ahead of print] doi:10.1038/s41593-020-0654-2
Epub:
Yes
Abstract:
During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess...
Organism or Cell Type:
zebrafish
Citation Extract:
Hughes AN, Appel B. Microglia phagocytose myelin sheaths to modify developmental myelination. Nat Neurosci. 2020;[Epub ahead of print] doi:10.1038/s41593-020-0654-2.

Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish

Authors:
Castanon I, Hannich JT, Abrami L, Huber F, Dubois M, Müller M, van der Goot FG, Gonzalez-Gaitan M
Citation:
Nat Commun. 2020 Jul 3;11(1):3317. doi:10.1038/s41467-020-17196-3
Epub:
Not Epub
Abstract:
Oriented cell division is a fundamental mechanism to control asymmetric stem cell division, neural tube elongation and body...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Castanon I, Hannich JT, Abrami L, Huber F, Dubois M, Müller M, van der Goot FG, Gonzalez-Gaitan M. Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish. Nat Commun. 2020 Jul 3;11(1):3317. doi:10.1038/s41467-020-17196-3.

Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2

Authors:
Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen MdN, Dwivedi SKD, Ramchandran R, Mukherjee P, Bhattacharya R
Citation:
Sci Adv. 2020;6(37):eaaz8534 [Epub] doi:10.1126/sciadv.aaz8534
Epub:
Not Epub
Abstract:
The stringent expression of the hypoxia inducible factor-1α (HIF-1α) is critical to a variety of pathophysiological conditions...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen MdN, Dwivedi SKD, Ramchandran R, Mukherjee P, Bhattacharya R. Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2. Sci Adv. 2020;6(37):eaaz8534 [Epub] doi:10.1126/sciadv.aaz8534 .

Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling

Authors:
Schmid S, Willi RA, Fent K
Citation:
Aquat Toxicol. 2020 Jul 3;226:105562. doi: 10.1016/j.aquatox.2020.105562. Online ahead of print.
Epub:
Yes
Abstract:
Fish are exposed to steroids of different classes in contaminated waters, but their effects are not sufficiently understood....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schmid S, Willi RA, Fent K. Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling. Aquat Toxicol. 2020 Jul 3;226:105562. doi: 10.1016/j.aquatox.2020.105562. Online ahead of print..

CYFIP2 containing WAVE complexes inhibit cell migration

Authors:
Polesskaya A, Boutillon A, Wang Y, Lavielle M, Vacher S, Schnitzler A, Molinie N, Rocques N, Fokin A, Bièche I, David NB, Gautreau AM
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.02.184655
Epub:
Not Epub
Abstract:
Branched actin networks polymerized by the Arp2/3 complex are critical for cell migration. The WAVE complex is the major Arp2/3...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Polesskaya A, Boutillon A, Wang Y, Lavielle M, Vacher S, Schnitzler A, Molinie N, Rocques N, Fokin A, Bièche I, David NB, Gautreau AM. CYFIP2 containing WAVE complexes inhibit cell migration. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.02.184655 .

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis

Authors:
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J
Citation:
Genes Dev. 2020 Jul 2. doi: 10.1101/gad.338178.120. Online ahead of print
Epub:
Yes
Abstract:
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
explant: murine pancreatic islets
Citation Extract:
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. A role for alternative splicing in circadian control of exocytosis and glucose homeostasis. Genes Dev. 2020 Jul 2. doi: 10.1101/gad.338178.120. Online ahead of print.

Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells

Authors:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP
Citation:
J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print
Epub:
Yes
Abstract:
In vascular smooth muscle cells (VMSCs), stimulation of Ca2+ -permeable canonical transient receptor potential channel 1 (TRPC1...
Organism or Cell Type:
cell culture: contractile rat mesenteric artery vascular smooth muscle cells (VMSCs)
Citation Extract:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP. Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells. J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print.

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