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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos
Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.07.013 Epub:
Not Epub Abstract:
Early embryonic development is driven exclusively by maternal gene products deposited into the oocyte. Although critical in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kushawah G, Hernandez-Huertas L, del Prado JA-N, Martinez-Morales JR, DeVore ML, Huzaifa Hassan H, Moreno-Sanchez I, Tomas-Gallardo L, Diaz-Moscoso A, Monges DE, Guelfo JR, Theune WC, Brannan EO, Wang W, Corbin TJ, Moran AM, Alvarado AS, Málaga-Trillo E, Takacs CM, Bazzini AA, Moreno-Mateos MA. CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.07.013. |
Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway
Citation:
Sci Rep. 2020 Aug 13;10(1):13752. doi: 10.1038/s41598-020-70670-2 Epub:
Not Epub Abstract:
Sproutys are negative regulators of the Ras/Raf/MAPK signaling pathway and involved in regulation of organogenesis,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Sun J, Yoon J, Lee M, Hwang YS, Daar IO. Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway. Sci Rep. 2020 Aug 13;10(1):13752. doi: 10.1038/s41598-020-70670-2. |
The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts
Citation:
Int J Mol Sci. 2020;21:5709. doi:10.3390/ijms21165709 Epub:
Not Epub Abstract:
The Cpi-17 (ppp1r14) gene family is an evolutionarily conserved, vertebrate specific group of protein phosphatase 1 (PP1)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lang I, Virk G, Zheng DC, Young J, Nguyen MJ, Amiri R, Fong M, Arata A, Chadaideh KS, Walsh S, Weiser DC. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Int J Mol Sci. 2020;21:5709. doi:10.3390/ijms21165709 . |
THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis
Citation:
PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953 Epub:
Not Epub Abstract:
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953. |
Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast
Citation:
PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414 Epub:
Not Epub Abstract:
The host innate immune system has developed elegant processes for the detection and clearance of invasive fungal pathogens.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scherer AK, Blair BA, Park J, Seman BG, Kelley JB, Wheeler RT. Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast. PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414. |
NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation
Citation:
J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275 Epub:
Not Epub Abstract:
The Nck-associated protein 1–like (NCKAP1L) gene, alternatively called hematopoietic protein 1 (HEM-1), encodes a hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castro CN, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, Miao Z, Groß M, Tranchant T, Radosavljevic M, Paul N, Stemmelen T, Pitoiset F, Hirschler A, Nespola B, Molitor A, Rolli V, Pichot A, Faletti LE, Rinaldi B, Friant S, Mednikov M, Karauzum H, Aman MJ, Carapito C, Lengerke C, Ziaee V, Eyaid W, Ehl S, Alroqi F, Parvaneh N, Bahram S. NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation. J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275. |
Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.05.238139 Epub:
Not Epub Abstract:
Inducing regeneration in injured spinal cord represents one of modern medicine’s greatest challenges. Research from a variety... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hamilton AM, Borodinsky LN. Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.05.238139. |
3D quantification of zebrafish cerebrovascular architecture by automated image analysis of light sheet fluorescence microscopy datasets
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.06.239905 Epub:
Not Epub Abstract:
Zebrafish transgenic lines and light sheet fluorescence microscopy allow in-depth insights into vascular development in vivo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kugler EC, Frost J, Silva V, Plant KC, Chhabria K, Chico TJ, Armitage P. 3D quantification of zebrafish cerebrovascular architecture by automated image analysis of light sheet fluorescence microscopy datasets. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.06.239905 . |
Systematic comparison of developmental GRNs explains how novelty is incorporated in early development
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.07.231464 Epub:
Not Epub Abstract:
The impressive array of morphological diversity among animal taxa represents the product of millions of years of evolution.... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Cary GA, McCauley BS, Zueva O, Pattinato J, Longabaugh W, Hinman VF. Systematic comparison of developmental GRNs explains how novelty is incorporated in early development. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.07.231464 . |
Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts
Citation:
Sci Rep. 2020 Aug 6;10(1):13254. doi:10.1038/s41598-020-69956-2 Epub:
Not Epub Abstract:
Understanding mechanisms mediating tumor metastasis is crucial for diagnostic and therapeutic targeting. Here, we take... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Asokan N, Daetwyler S, Bernas SN, Schmied C, Vogler S, Lambert K, Wobus M, Wermke M, Kempermann G, Huisken J, Brand M, Bornhäuser M. Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts. Sci Rep. 2020 Aug 6;10(1):13254. doi:10.1038/s41598-020-69956-2. |