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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulates the retinal endothelial cell barrier

Authors:
McGuire PG, Rangasamy S, Maestas J, Das A
Citation:
Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):e107-15. Epub 2011 Sep 22
Epub:
Not Epub
Abstract:
OBJECTIVE: The mechanisms that regulate the physical interaction of pericytes and endothelial cells and the effects of these...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human retinal cells
Citation Extract:
McGuire PG, Rangasamy S, Maestas J, Das A. Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulates the retinal endothelial cell barrier. Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):e107-15. Epub 2011 Sep 22.

PINCH proteins regulate cardiac contractility by modulating ILK-PKB signaling

Authors:
Meder B, Huttner IG, Sedaghat-Hamedani F, Just S, Dahme T, Frese KS, Vogel B, Köhler D, Kloos W, Rudloff J, Marquart S, Katus HA, Rottbauer W
Citation:
Mol Cell Biol. 2011 Jun 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Integrin-linked kinase (ILK) is an essential component of the cardiac mechanical stretch sensor, and is bound in a protein...
Organism or Cell Type:
zebrafish
Citation Extract:
Meder B, Huttner IG, Sedaghat-Hamedani F, Just S, Dahme T, Frese KS, Vogel B, Köhler D, Kloos W, Rudloff J, Marquart S, Katus HA, Rottbauer W. PINCH proteins regulate cardiac contractility by modulating ILK-PKB signaling. Mol Cell Biol. 2011 Jun 13. [Epub ahead of print].

Postsynaptic TRPC1 Function Contributes to BDNF-Induced Synaptic Potentiation at the Developing Neuromuscular Junction

Authors:
McGurk JS, Shim S, Kim JY, Wen Z, Song H, Ming GL
Citation:
J Neurosci. 2011;31(41):14754-14762 doi:10.1523/JNEUROSCI.3599-11.2011
Epub:
Not Epub
Abstract:
Brain-derived neurotrophic factor (BDNF) induces synaptic potentiation at both neuromuscular junctions (NMJs) and synapses of...
Organism or Cell Type:
Xenopus
Citation Extract:
McGurk JS, Shim S, Kim JY, Wen Z, Song H, Ming GL. Postsynaptic TRPC1 Function Contributes to BDNF-Induced Synaptic Potentiation at the Developing Neuromuscular Junction. J Neurosci. 2011;31(41):14754-14762 doi:10.1523/JNEUROSCI.3599-11.2011 .

Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction

Authors:
Mercader N, Fischer S, Neumann CJ
Citation:
Development. 2006 Aug;133(15):2805-15. Epub 2006 Jun 21
Epub:
Not Epub
Abstract:
Vertebrate limb induction is triggered in the lateral plate mesoderm (LPM) by a cascade of signaling events originating in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mercader N, Fischer S, Neumann CJ. Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction. Development. 2006 Aug;133(15):2805-15. Epub 2006 Jun 21.

Pronephric tubulogenesis requires Daam1-mediated planar cell polarity signaling

Authors:
Miller RK, Canny SG, Jang CW, Cho K, Ji H, Wagner DS, Jones EA, Habas R, McCrea PD
Citation:
J Am Soc Nephrol. 2011 Sep;22(9):1654-64. Epub 2011 Jul 29
Epub:
Not Epub
Abstract:
Canonical β-catenin-mediated Wnt signaling is essential for the induction of nephron development. Noncanonical Wnt/planar cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish, Xenopus
Citation Extract:
Miller RK, Canny SG, Jang CW, Cho K, Ji H, Wagner DS, Jones EA, Habas R, McCrea PD. Pronephric tubulogenesis requires Daam1-mediated planar cell polarity signaling. J Am Soc Nephrol. 2011 Sep;22(9):1654-64. Epub 2011 Jul 29.

Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins

Authors:
Mercader N, Tanaka EM, Torres M
Citation:
Development. 2005 Sep;132(18):4131-42. Epub 2005 Aug 17
Epub:
Not Epub
Abstract:
The mechanisms by which cells obtain instructions to precisely re-create the missing parts of an organ remain an unresolved...
Delivery Method:
Microinjection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Mercader N, Tanaka EM, Torres M. Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins. Development. 2005 Sep;132(18):4131-42. Epub 2005 Aug 17.

Quantitation of Intracellular Concentration of a Delivered Morpholino Oligomer by Capillary Electrophoresis-Laser- Induced Fluorescence: Correlation with Upregulation of Luciferase Gene Expression

Authors:
McKeon J, Cho MJ, Khaledi MG
Citation:
Anal Biochem 2001 Jun 1;293(1):1-7
Epub:
Not Epub
Abstract:
Antisense oligonucleotides have shown great promise over the past several years as viable drugs to combat various forms of...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
McKeon J, Cho MJ, Khaledi MG. Quantitation of Intracellular Concentration of a Delivered Morpholino Oligomer by Capillary Electrophoresis-Laser- Induced Fluorescence: Correlation with Upregulation of Luciferase Gene Expression. Anal Biochem 2001 Jun 1;293(1):1-7.

Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling

Authors:
Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, DeGraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD
Citation:
Sci Transl Med. 2009;1(3):3ra7
Epub:
Not Epub
Abstract:
Radiation-induced damage of normal tissues restricts the therapeutic doses of ionizing radiation that can be delivered to...
Organism or Cell Type:
cell culture, mice
Citation Extract:
Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, DeGraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD. Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling. Sci Transl Med. 2009;1(3):3ra7.

Regulation of cytokinesis by Rho GTPase flux

Authors:
Miller AL, Bement WM
Citation:
Nat Cell Biol. 2009 Jan;11(1):71-7. Epub 2008 Dec 7
Epub:
Not Epub
Abstract:
In animal cells, cytokinesis is powered by a contractile ring of actin filaments (F-actin) and myosin-2. Formation of the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Miller AL, Bement WM. Regulation of cytokinesis by Rho GTPase flux. Nat Cell Biol. 2009 Jan;11(1):71-7. Epub 2008 Dec 7.

Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development

Authors:
McLin VA, Rankin SA, Zorn AM
Citation:
Development. 2007 Jun;134(12):2207-17. Epub 2007 May 16
Epub:
Not Epub
Abstract:
The liver and pancreas are specified from the foregut endoderm through an interaction with the adjacent mesoderm. However, the...
Organism or Cell Type:
Xenopus
Citation Extract:
McLin VA, Rankin SA, Zorn AM. Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development. 2007 Jun;134(12):2207-17. Epub 2007 May 16.

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