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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

High-Resolution Optical Imaging of Zebrafish Larval Ribbon Synapse Protein RIBEYE, RIM2, and CaV 1.4 by Stimulation Emission Depletion Microscopy

Authors:
Lv C, Gould TJ, Bewersdorf J, Zenisek D
Citation:
Microsc Microanal. 2012 Jul 26:1-8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The synaptic ribbon is a unique presynaptic structure with an intricate morphology in photoreceptors. Because of the resolution...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lv C, Gould TJ, Bewersdorf J, Zenisek D. High-Resolution Optical Imaging of Zebrafish Larval Ribbon Synapse Protein RIBEYE, RIM2, and CaV 1.4 by Stimulation Emission Depletion Microscopy. Microsc Microanal. 2012 Jul 26:1-8. [Epub ahead of print].

Huntingtin-deficient zebrafish exhibit defects in iron utilization and development

Authors:
Lumsden AL, Henshall TL, Dayan S, Lardelli MT, Richards RI
Citation:
Hum Mol Genet. 2007 Aug 15;16(16):1905-20. Epub 2007 Jun 13
Epub:
Not Epub
Abstract:
Huntington's disease is one of nine neurodegenerative disorders caused by expansion of CAG repeats encoding polyglutamine...
Organism or Cell Type:
zebrafish
Citation Extract:
Lumsden AL, Henshall TL, Dayan S, Lardelli MT, Richards RI. Huntingtin-deficient zebrafish exhibit defects in iron utilization and development. Hum Mol Genet. 2007 Aug 15;16(16):1905-20. Epub 2007 Jun 13.

In vivo correction of a Menkes disease model using antisense oligonucleotides

Authors:
Madsen EC, Morcos PA, Mendelsohn BA, Gitlin JD
Citation:
Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3909-14. Epub 2008 Mar 3.
Epub:
Not Epub
Abstract:
Although the molecular basis of many inherited metabolic diseases has been defined, the availability of effective therapies in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Madsen EC, Morcos PA, Mendelsohn BA, Gitlin JD. In vivo correction of a Menkes disease model using antisense oligonucleotides. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3909-14. Epub 2008 Mar 3..

Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development

Authors:
Luo T, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD
Citation:
Development. 2007 Apr;134(7):1279-89. Epub 2007 Feb 21.
Epub:
Not Epub
Abstract:
Inca (induced in neural crest by AP2) is a novel protein discovered in a microarray screen for genes that are upregulated in...
Citation Extract:
Luo T, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development. 2007 Apr;134(7):1279-89. Epub 2007 Feb 21..

Induction of neural crest in Xenopus by transcription factor AP2{alpha}

Authors:
Luo T, Lee YH, Saint-Jeannet JP, Sargent TD
Citation:
Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):532-7. Epub 2003 Jan 02
Epub:
Not Epub
Abstract:
We report experiments with Xenopus laevis, using both intact embryos and ectodermal explants, showing that the transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Luo T, Lee YH, Saint-Jeannet JP, Sargent TD. Induction of neural crest in Xenopus by transcription factor AP2{alpha}. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):532-7. Epub 2003 Jan 02.

Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers

Authors:
Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M
Citation:
Arch Virol. 2008 May;153(5):929-37. Epub 2008 Mar 28
Epub:
Not Epub
Abstract:
New methods to combat influenza A virus (FLUAV) in humans and animals are needed. The H3N8 subtype virus was the cause of the...
Delivery Method:
Peptide-coupled intranasal
Organism or Cell Type:
mice
Citation Extract:
Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M. Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers. Arch Virol. 2008 May;153(5):929-37. Epub 2008 Mar 28.

Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs

Authors:
Ma W, Lin Y, Xuan W, Iversen PL, Smith LJ, Benchimol S
Citation:
Oncogene. 2011 [Epub ahead of print 18 July] doi: 10.1038/onc.2011.300
Epub:
Not Epub
Abstract:
The p53 tumor suppressor gene encodes a transcription factor that is commonly mutated in cancer. Tumors arise when premalignant...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: H460
Citation Extract:
Ma W, Lin Y, Xuan W, Iversen PL, Smith LJ, Benchimol S. Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs. Oncogene. 2011 [Epub ahead of print 18 July] doi: 10.1038/onc.2011.300.

Jagged2a-notch signaling mediates cell fate choice in the zebrafish pronephric duct

Authors:
Ma M, Jiang YJ
Citation:
PLoS Genet. 2007 Jan 26;3(1):e18
Epub:
Not Epub
Abstract:
Pronephros, a developmental model for adult mammalian kidneys (metanephros) and a functional kidney in early teleosts, consists...
Organism or Cell Type:
zebrafish
Citation Extract:
Ma M, Jiang YJ. Jagged2a-notch signaling mediates cell fate choice in the zebrafish pronephric duct. PLoS Genet. 2007 Jan 26;3(1):e18.

KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome

Authors:
Lyons DA, Naylor SG, Mercurio S, Dominguez C, Talbot WS
Citation:
Development. 2008 Feb;135(3):599-608
Epub:
Not Epub
Abstract:
Mutations in Kif1-binding protein/KIAA1279 (KBP) cause the devastating neurological disorder Goldberg-Shprintzen syndrome (GSS...
Organism or Cell Type:
zebrafish
Citation Extract:
Lyons DA, Naylor SG, Mercurio S, Dominguez C, Talbot WS. KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome. Development. 2008 Feb;135(3):599-608.

Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons

Authors:
Lyons DA, Naylor SG, Scholze A, Talbot WS
Citation:
Nat Genet. 2009 Jul;41(7):854-8. Epub 2009 Jun 7
Epub:
Not Epub
Abstract:
The kinesin motor protein Kif1b has previously been implicated in the axonal transport of mitochondria and synaptic vesicles....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lyons DA, Naylor SG, Scholze A, Talbot WS. Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons. Nat Genet. 2009 Jul;41(7):854-8. Epub 2009 Jun 7.

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