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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Kinetic Mechanisms in Morpholino-DNA Surface Hybridization

Authors:
Liu Y, Irving D, Qiao W, Ge D, Levicky R
Citation:
J. Am. Chem. Soc. 2011;[Epub ahead of print] DOI: 10.1021/ja202631b
Epub:
Not Epub
Abstract:
Morpholinos (MOs) are DNA analogues whose uncharged nature can bring fundamental advantages to surface hybridization...
Delivery Method:
species. Advancement of MO-based diagnostics
Organism or Cell Type:
however
Citation Extract:
Liu Y, Irving D, Qiao W, Ge D, Levicky R. Kinetic Mechanisms in Morpholino-DNA Surface Hybridization. J. Am. Chem. Soc. 2011;[Epub ahead of print] DOI: 10.1021/ja202631b.

Knockdown of Leptin A Expression Dramatically Alters Zebrafish Development

Authors:
Liu Q, Dalman M, Chen Y, Akhter M, Brahmandam S, Patel Y, Lowe J, Thakkar M, Gregory AV, Phelps D, Riley C, Londraville RL
Citation:
Gen Comp Endocrinol. 2012;[Epub ahead of print] doi:10.1016/j.ygcen.2012.07.011
Epub:
Not Epub
Abstract:
Using morpholino antisense oligonucleotide (MO) technology, we blocked leptin A or leptin receptor expression in embryonic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Q, Dalman M, Chen Y, Akhter M, Brahmandam S, Patel Y, Lowe J, Thakkar M, Gregory AV, Phelps D, Riley C, Londraville RL. Knockdown of Leptin A Expression Dramatically Alters Zebrafish Development. Gen Comp Endocrinol. 2012;[Epub ahead of print] doi:10.1016/j.ygcen.2012.07.011.

Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis.

Authors:
Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT
Citation:
Dev Cell. 2003 Dec;5(6):903-14
Epub:
Not Epub
Abstract:
Mechanisms underlying the multiple developmental defects observed in Fanconi anemia (FA) patients are not well defined. We have...
Delivery Method:
microinjection in embryos, Special Delivery in culture
Organism or Cell Type:
Zebrafish embryos and cultured zebrafish fibroblast AB9 cells
Citation Extract:
Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis.. Dev Cell. 2003 Dec;5(6):903-14.

Leukocyte tyrosine kinase functions in pigment cell development

Authors:
Lopes SS, Yang X, Müller J, Carney TJ, McAdow AR, Rauch GJ, Jacoby AS, Hurst LD, Delfino-Machín M, Haffter P, Geisler R, Johnson SL, Ward A, Kelsh RN
Citation:
PLoS Genet. 2008 Mar 7;4(3):e1000026
Epub:
Not Epub
Abstract:
A fundamental problem in developmental biology concerns how multipotent precursors choose specific fates. Neural crest cells (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lopes SS, Yang X, Müller J, Carney TJ, McAdow AR, Rauch GJ, Jacoby AS, Hurst LD, Delfino-Machín M, Haffter P, Geisler R, Johnson SL, Ward A, Kelsh RN. Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genet. 2008 Mar 7;4(3):e1000026.

Lysophosphatidic acid signaling controls cortical actin assembly and cytoarchitecture in Xenopus embryos

Authors:
Lloyd B, Tao Q, Lang S, Wylie C
Citation:
Development. 2005 Feb;132(4):805-16. Epub 2005 Jan 19
Epub:
Not Epub
Abstract:
The mechanisms that control shape and rigidity of early embryos are not well understood, and yet are required for all embryonic...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lloyd B, Tao Q, Lang S, Wylie C. Lysophosphatidic acid signaling controls cortical actin assembly and cytoarchitecture in Xenopus embryos. Development. 2005 Feb;132(4):805-16. Epub 2005 Jan 19.

MicroRNA-206 regulates cell movements during zebrafish gastrulation by targeting prickle1a and regulating JNK2 phosphorylation

Authors:
Liu X, Ning G, Meng A, Wang Q
Citation:
Mol Cell Biol. 2012 May 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During vertebrate gastrulation, both concurrent inductive events and cell movements are required for axis formation....
Organism or Cell Type:
zebrafish
Citation Extract:
Liu X, Ning G, Meng A, Wang Q. MicroRNA-206 regulates cell movements during zebrafish gastrulation by targeting prickle1a and regulating JNK2 phosphorylation. Mol Cell Biol. 2012 May 21. [Epub ahead of print].

MIM regulates vertebrate neural tube closure

Authors:
Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R
Citation:
Development. 2011 May;138(10):2035-47. Epub 2011 Apr 6
Epub:
Not Epub
Abstract:
Neural tube closure is a critical morphogenetic event that is regulated by dynamic changes in cell shape and behavior. Although...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R. MIM regulates vertebrate neural tube closure. Development. 2011 May;138(10):2035-47. Epub 2011 Apr 6.

Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1

Authors:
Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN
Citation:
PLoS ONE. 2009;4(2):e4310. Epub 2009 Feb 2
Epub:
Not Epub
Abstract:
BACKGROUND: Wnts are evolutionarily conserved ligands that signal through beta-catenin-dependent and beta-catenin-independent...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN. Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1. PLoS ONE. 2009;4(2):e4310. Epub 2009 Feb 2.

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development

Authors:
Liu Y, Xu XH, Chen Q, Wang T, Deng CY, Song BL, Du JL, Luo ZG
Citation:
Nat Commun. 2013 Jun 17;4:2005. doi: 10.1038/ncomms3005
Epub:
Not Epub
Abstract:
Polarized membrane addition is crucial for axon development and elongation during neuronal morphogenesis. This process is...
Delivery Method:
in vitro: intravitreal injection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Xu XH, Chen Q, Wang T, Deng CY, Song BL, Du JL, Luo ZG. Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development. Nat Commun. 2013 Jun 17;4:2005. doi: 10.1038/ncomms3005.

Nanoconjugate based on polymalic acid for tumor targeting

Authors:
Ljubimova JY, Fujita M, Khazenzon NM, Lee BS, Wachsmann-Hogiu S, Farkas DL, Black KL, Holler E
Citation:
Chem Biol Interact. 2008 Jan 30;171(2):195-203. Epub 2007 Feb 8.
Epub:
Not Epub
Abstract:
A new prototype of polymer-derived drug delivery system, the nanoconjugate Polycefin, was tested for its ability to accumulate...
Delivery Method:
Polycefin: poly(malic acid) from Physarum polycephalum
Organism or Cell Type:
mice, nude
Citation Extract:
Ljubimova JY, Fujita M, Khazenzon NM, Lee BS, Wachsmann-Hogiu S, Farkas DL, Black KL, Holler E. Nanoconjugate based on polymalic acid for tumor targeting. Chem Biol Interact. 2008 Jan 30;171(2):195-203. Epub 2007 Feb 8..

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