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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Dishevelled2 Is a Stable Protein During Early Zebrafish Development
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Citation:
Zebrafish. 2011 [Epub ahead of print] doi:10.1089/zeb.2011.0691 Epub:
Not Epub Abstract:
Wnt signaling is a major player during development and its misregulation often leads to disease, especially cancer. The... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Lum WM, Robertson JK, Van Raay TJ. Dishevelled2 Is a Stable Protein During Early Zebrafish Development. Zebrafish. 2011 [Epub ahead of print] doi:10.1089/zeb.2011.0691. |
Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway
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Citation:
Development. 2010 Jan 7. [Epub ahead of print] Epub:
Not Epub Abstract:
The vertebrate body plan is established in two major steps. First, mesendoderm induction singles out prospective endoderm,... Organism or Cell Type:
Xenopus Citation Extract: Luxardi G, Marchal L, Thomé V, Kodjabachian L. Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway. Development. 2010 Jan 7. [Epub ahead of print]. |
Dominant mutation of CCDC78 in a unique congenital myopathy with prominent internal nuclei and atypical cores
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Citation:
Am J Hum Genet. 2012 Aug 10;91(2):365-71. doi: 10.1016/j.ajhg.2012.06.012. Epub 2012 Jul 19 Epub:
Not Epub Abstract:
Congenital myopathies are clinically and genetically heterogeneous diseases that typically present in childhood with hypotonia... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Majczenko K, Davidson AE, Camelo-Piragua S, Agrawal PB, Manfready RA, Li X, Joshi S, Xu J, Peng W, Beggs AH, Li JZ, Burmeister M, Dowling JJ. Dominant mutation of CCDC78 in a unique congenital myopathy with prominent internal nuclei and atypical cores. Am J Hum Genet. 2012 Aug 10;91(2):365-71. doi: 10.1016/j.ajhg.2012.06.012. Epub 2012 Jul 19. |
Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice
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Citation:
Hum Gene Ther. 2009 Sep;20(9):955-65. Epub:
Not Epub Abstract:
Duchenne Muscular Dystrophy (DMD) is a myodegenerative disorder caused primarily by mutations that create premature termination... Delivery Method:
in vivo: injection Organism or Cell Type:
mice, mdx Citation Extract: Malerba A, Thorogood FC, Dickson G, Graham IR. Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice. Hum Gene Ther. 2009 Sep;20(9):955-65.. |
DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1
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Citation:
Cell. 2008 Jun 27;133(7):1241-54 Epub:
Not Epub Abstract:
During nervous system development, spinal commissural axons project toward and across the ventral midline. They are guided in... Organism or Cell Type:
Xenopus Citation Extract: Ly A, Nikolaev A, Suresh G, Zheng Y, Tessier-Lavigne M, Stein E. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell. 2008 Jun 27;133(7):1241-54. |
Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy
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Citation:
Mol Ther Nucleic Acids. 2012;1:e62. doi:/10.1038/mtna.2012.54 Epub:
Not Epub Abstract:
The knockdown of myostatin, a negative regulator of skeletal muscle mass may have important implications in disease conditions... Delivery Method:
Vivo-Morpholino oligos and peptide coupled oligos Organism or Cell Type:
mice, mdx and normal Citation Extract: Malerba A, Kang JK, McClorey G, Saleh AF, Popplewell L, Gait MJ, Wood MJA, Dickson G. Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2012;1:e62. doi:/10.1038/mtna.2012.54. |
Dystroglycan is required for proper retinal layering
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Citation:
Dev Biol. 2006 Feb 15;290(2):411-20. Epub 2006 Jan 9. Epub:
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Dystroglycan (DG) is a transmembrane receptor linking the extracellular matrix to the internal cytoskeleton. Its structural... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lunardi A, Cremisi F, Dente L. Dystroglycan is required for proper retinal layering. Dev Biol. 2006 Feb 15;290(2):411-20. Epub 2006 Jan 9.. |
Eafs Control Erythroid Cell Fate by Regulating c-myb Expression through Wnt Signaling
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Citation:
PLoS ONE 2013;8(5):e64576. doi:10.1371/journal.pone.0064576 Epub:
Not Epub Abstract:
ELL associated factor 1 and ELL associated factor 2 (EAF1/2 factors) are reported to play important roles in tumor suppression... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma X, Liu J-X. Eafs Control Erythroid Cell Fate by Regulating c-myb Expression through Wnt Signaling. PLoS ONE 2013;8(5):e64576. doi:10.1371/journal.pone.0064576. |
Early transcriptional targets of MyoD link myogenesis and somitogenesis
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Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.08.027 Epub:
Not Epub Abstract:
In order to identify early transcriptional targets of MyoD prior to skeletal muscle differentiation, we have undertaken a... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Maguire RJ, Isaacs HV, Pownall ME. Early transcriptional targets of MyoD link myogenesis and somitogenesis. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.08.027. |
Endometrial calbindins are critical for embryo implantation: Evidence from in vivo use of morpholino antisense oligonucleotides
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Citation:
Proc Natl Acad Sci U S A. 2004 May 25;101(21):8028-33. Epub:
Not Epub Abstract:
The endometrium is receptive to embryo implantation only for a short period in each reproductive cycle: development of... Delivery Method:
in vivo: injection Organism or Cell Type:
mice Citation Extract: Luu KC, Nie GY, Salamonsen LA. Endometrial calbindins are critical for embryo implantation: Evidence from in vivo use of morpholino antisense oligonucleotides. Proc Natl Acad Sci U S A. 2004 May 25;101(21):8028-33.. |